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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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D275774-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $176.90 | |
D275774-500μg | 500μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $681.90 |
Morphogen. Inhibits cancer cell line proliferation and induces cell differentiation.
Synonyms | Q27133348 | DIF 1 | Differentiation-inducing factor 1 | DIF-1 | DIF factor | C13H16Cl2O4 | DTXSID10149474 | Morphogen differentiation inducing factor (dictyostelium) | 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one | Dif-1 (dictyostelium) | 1-( |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Morphogen that induces differentiation of Dictyostelium discoideum . Inhibits proliferation of cancer cell lines by suppressing Wnt/ β-catenin signaling pathway. Also induces tumor cell differentiation. |
Storage Temp | Store at -20°C,Desiccated |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one |
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INCHI | InChI=1S/C13H16Cl2O4/c1-3-4-5-6-7(16)8-11(17)9(14)13(19-2)10(15)12(8)18/h17-18H,3-6H2,1-2H3 |
InChi Key | VUDQSRFCCHQIIU-UHFFFAOYSA-N |
Canonical SMILES | CCCCCC(=O)C1=C(C(=C(C(=C1O)Cl)OC)Cl)O |
Isomeric SMILES | CCCCCC(=O)C1=C(C(=C(C(=C1O)Cl)OC)Cl)O |
PubChem CID | 123886 |
Molecular Weight | 307.2 |
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Solubility | Soluble in DMSO to 50 mM |
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