Difluoromethylornithine - ≥98%, high purity , CAS No.66640-93-5

  • ≥98%
Item Number
D275915
Grouped product items
SKUSizeAvailabilityPrice Qty
D275915-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$80.90
D275915-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$147.90

Irreversible ornithine decarboxylase inhibitor

Basic Description

SynonymsL-EFLORNITHINE | 66640-93-5 | (S)-2,5-diamino-2-(difluoromethyl)pentanoic acid | 66640-93-5 (L-isomer) | (-)-2-Difluoromethylornithine | (2S)-2,5-diamino-2-(difluoromethyl)pentanoic acid | L-Ornithine, 2-(difluoromethyl)- | C780YUS9YI | (S)-eflornithine | L-DFMO | L-a-difluo
Specifications & Purity≥98%
Biochemical and Physiological MechanismsPotent, irreversible ornithine decarboxylase inhibitor (K i = 39 μM). Depletes polyamines in vitro . Antineoplastic, cytotoxic and trypanocidal agent. Orally active. Active in vivo and in vitro .
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets(Human)

ODC1 Tclin Ornithine decarboxylase (70 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Trypanosoma brucei (78846 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania donovani (89745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei gambiense (523 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei rhodesiense (7991 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma evansi (198 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2S)-2,5-diamino-2-(difluoromethyl)pentanoic acid
INCHI InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12)/t6-/m1/s1
InChi Key VLCYCQAOQCDTCN-ZCFIWIBFSA-N
Canonical SMILES C(CC(C(F)F)(C(=O)O)N)CN
Isomeric SMILES C(C[C@@](C(F)F)(C(=O)O)N)CN
PubChem CID 6992039

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water

Related Documents

Solution Calculators