Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D135863-250mg | 250mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,398.90 |
Synonyms | C33H37N5O5.CH3SO3H | D.H.E. 45 | Dihydergot | Dihydroergotamine mesilate | DIHYDROERGOTAMINE MESYLATE [USP MONOGRAPH] | DIHYDROERGOTAMINE MESYLATE [USP-RS] | NSC759848 | NSC-759848 | Dihydroergotamine mesylate | KBio3_002188 | ST056346 | (2r,4r,7r)-n-[(1s |
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Specifications & Purity | Moligand™, pharmaceutical grade |
Shipped In | Normal |
Grade | Moligand™, pharmaceutical grade |
Action Type | AGONIST, ANTAGONIST |
Mechanism of action | Agonist of 5-HT 1B receptor;Agonist of 5-HT 1D receptor;Agonist of 5-ht 1e receptor;Agonist of 5-HT 1F receptor;Antagonist of 5-HT 6 receptor;Antagonist of 5-HT 7 receptor |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (6aR,9R,10aR)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide;methanesulfonic acid |
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INCHI | InChI=1S/C33H37N5O5.CH4O3S/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32;1-5(2,3)4/h3-6,8-11,17,21,23,25-27,34,42H,7,12-16,18H2,1-2H3,(H,35,39);1H3,(H,2,3,4)/t21-,23-,25-,26+,27+,32-,33+;/m1./s1 |
InChi Key | ADYPXRFPBQGGAH-UMYZUSPBSA-N |
Canonical SMILES | CC1(C(=O)N2C(C(=O)N3CCCC3C2(O1)O)CC4=CC=CC=C4)NC(=O)C5CC6C(CC7=CNC8=CC=CC6=C78)N(C5)C.CS(=O)(=O)O |
Isomeric SMILES | C[C@@]1(C(=O)N2[C@H](C(=O)N3CCC[C@H]3[C@@]2(O1)O)CC4=CC=CC=C4)NC(=O)[C@@H]5C[C@H]6[C@@H](CC7=CNC8=CC=CC6=C78)N(C5)C.CS(=O)(=O)O |
RTECS | KE7920000 |
PubChem CID | 71171 |
Molecular Weight | 679.79 |
Reaxy-Rn | 6473411 |
PubChem CID | 10531 |
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ChEMBL Ligand | CHEMBL1732 |
DrugBank Ligand | DB00320 |
Wikipedia | Dihydroergotamine |
CAS Registry No. | 6190-39-2 |
ChEBI | CHEBI:4562 |
RCSB PDB Ligand | 2GM |
DrugCentral Ligand | 888 |
GPCRdb Ligand | dihydroergotamine |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H312:Harmful in contact with skin H332:Harmful if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P317:Get emergency medical help. |
RTECS | KE7920000 |
Reaxy-Rn | 6473411 |