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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D651092-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $120.90 | |
D651092-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $210.90 | |
D651092-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $390.90 |
Alkaloids Isoquinoline Alkaloids
Synonyms | BERBINE, 13,13a-DIDEHYDRO-9,10-DIMETHOXY-2,3-(METHYLENEDIOXY)- | Dihydroberberine | CS-0018246 | Dihydroberberine/dihydroumbellatine | lambertin | 3bti | 9,10-Dimethoxy-5,8-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline | Dihydroberbine | FT-07 |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Dihydroberberine inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces heat shock protein 90 (Hsp90) expression and its interaction with hERG. Dihydroberberine has anti-inflammatory, anti-atherosclerotic, hypolipidemic and antit |
Storage Temp | Store at 2-8°C,Protected from light,Desiccated |
Shipped In | Wet ice |
Product Description | Dihydroberberine inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces heat shock protein 90 (Hsp90) expression and its interaction with hERG. Dihydroberberine has anti-inflammatory, anti-atherosclerotic, hypolipidemic and antitumor activities Form:Solid IC50& Target:HSP90 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 16,17-dimethoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(21),2,4(8),9,15(20),16,18-heptaene |
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INCHI | InChI=1S/C20H19NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,7-9H,5-6,10-11H2,1-2H3 |
InChi Key | FZAGOOYMTPGPGF-UHFFFAOYSA-N |
Canonical SMILES | COC1=C(C2=C(C=C1)C=C3C4=CC5=C(C=C4CCN3C2)OCO5)OC |
Isomeric SMILES | COC1=C(C2=C(C=C1)C=C3C4=CC5=C(C=C4CCN3C2)OCO5)OC |
Alternate CAS | 120834-89-1,483-15-8 |
PubChem CID | 10217 |
NSC Number | 331264 |
MeSH Entry Terms | dihydroberberine;dihydroberberine hydrochloride |
Molecular Weight | 337.37 |
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Solubility | DMSO : 20 mg/mL (59.28 mM; ultrasonic and warming and heat to 70°C) |
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