Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D131281-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $47.90 | |
D131281-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $147.90 | |
D131281-500mg | 500mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $662.90 |
Generic chloride channel blocker.
Synonyms | 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt | 4,4'-diisothiocyanatostilbene-2,2'-disul-fonic acid disodium salt | 1VFRQ7416A | 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic Acid, Disodium Salt | Disodium 4,4'-diisothiocyanatostilbene-2, |
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Specifications & Purity | ≥90%(HPLC) |
Biochemical and Physiological Mechanisms | 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is an anionic alkylating agent containing isothiocyanate residue. It is a negatively charged homobifunctional cross-linking reagent. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is a specific inhibi |
Storage Temp | Store at 2-8°C,Argon charged |
Shipped In | Wet ice |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Amine-Reactive fluorescent probe 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate has been used: · as band3 protein inhibitor in rabbits(19) · for the inhibition of bicarbonate transporters in brain slice tissue(20) · as HCO3-/Cl- exchanger (anion exchanger) in embryos(21) |
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IUPAC Name | disodium;5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfonatophenyl)ethenyl]benzenesulfonate |
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INCHI | InChI=1S/C16H10N2O6S4.2Na/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24;;/h1-8H,(H,19,20,21)(H,22,23,24);;/q;2*+1/p-2/b2-1+;; |
InChi Key | GEPAYBXVXXBSKP-SEPHDYHBSA-L |
Canonical SMILES | C1=CC(=C(C=C1N=C=S)S(=O)(=O)[O-])C=CC2=C(C=C(C=C2)N=C=S)S(=O)(=O)[O-].[Na+].[Na+] |
Isomeric SMILES | C1=CC(=C(C=C1N=C=S)S(=O)(=O)[O-])/C=C/C2=C(C=C(C=C2)N=C=S)S(=O)(=O)[O-].[Na+].[Na+] |
PubChem CID | 5702690 |
Molecular Weight | 498.47 |
Reaxy-Rn | 8179433 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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J2225362 | Certificate of Analysis | Aug 19, 2024 | D131281 |
J2225363 | Certificate of Analysis | Aug 19, 2024 | D131281 |
J2225364 | Certificate of Analysis | Aug 19, 2024 | D131281 |
K2108532 | Certificate of Analysis | Jan 02, 2024 | D131281 |
K2108530 | Certificate of Analysis | Aug 14, 2023 | D131281 |
K2108531 | Certificate of Analysis | Aug 14, 2023 | D131281 |
Sensitivity | Moisture sensitive; Light sensitive |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
Reaxy-Rn | 8179433 |