Dothiepin hydrochloride - ≥95%, high purity , CAS No.897-15-4

  • ≥95%
Item Number
D336042
Grouped product items
SKUSizeAvailabilityPrice Qty
D336042-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$181.90
D336042-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$653.90
D336042-500mg
500mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$2,939.90
D336042-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$5,291.90

a tricyclic antidepressant

Basic Description

SynonymsCHEBI:36805 | Dothiepin hydrochloride | 11-[3-(Dimethylamino)propylidene]-6,e]thiepine hydrochloride | 1-Propanamine,e]thiepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride | AKOS000321190 | DOSULEPIN HYDROCHLORIDE [JAN] | Dothiepin Hydrochloride; Dosulepin
Specifications & Purity≥95%
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Dothiepin hydrochloride is a tricyclic antidepressant.

Associated Targets(Human)

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Huh-7 (12904 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATXN2 Tbio Ataxin-2 (54410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Middle East respiratory syndrome-related coronavirus (220 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (3E)-3-(6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride
INCHI InChI=1S/C19H21NS.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H/b17-11+;
InChi Key XUPZAARQDNSRJB-SJDTYFKWSA-N
Canonical SMILES CN(C)CCC=C1C2=CC=CC=C2CSC3=CC=CC=C31.Cl
Isomeric SMILES CN(C)CC/C=C/1\C2=CC=CC=C2CSC3=CC=CC=C31.Cl
WGK Germany 3
RTECS HQ2975000
PubChem CID 9884029
Molecular Weight 331.90

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
J2209325Certificate of AnalysisAug 10, 2022 D336042
J2209335Certificate of AnalysisAug 10, 2022 D336042
J2209336Certificate of AnalysisAug 10, 2022 D336042
J2209337Certificate of AnalysisAug 10, 2022 D336042

Chemical and Physical Properties

SolubilitySoluble in DMSO (≥26 mg/mL), water (1:2), alcohol (1:8), and chloroform (1:2).
Refractive Indexn20D~1.66 (Predicted)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

WGK Germany 3
RTECS HQ2975000
Merck Index 2.96458333333333

Related Documents

Solution Calculators