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Doxercalciferol - 98%, high purity , Vitamin D receptor agonist, CAS No.54573-75-0, Vitamin D receptor agonist

Moligand™
≥98%

CAS#: 54573-75-0
Formula: C₂₈H₄₄O₂
Molecular Weight: 412.65
MDL number: MFCD00871065
PubChem CID: 5281107

Item Number

D120130

Grouped product items
SKU	Size	Availability	Price
D120130-1mg	1mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$24.90
D120130-5mg	5mg	In stock	$103.90
D120130-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$351.90

Vitamin D2analog, VDR agonist

View related series

Vitamin D receptor Agonist

Basic Description

Synonyms	Doxercalciferol\|54573-75-0\|Hectorol\|1-Hydroxyergocalciferol\|1alpha-Hydroxyergocalciferol\|1alpha-hydroxyvitamin D2\|TSA 840\|1-alpha-Hydroxyvitamin D2\|1-alpha-hydroxyergocalciferol\|1-Hydroxyvitamin D2\|Doxercalciferolum\|UNII-3DIZ9LF5Y9\|3DIZ9LF5Y9\|1.alpha.-Hyd
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Vitamin D2analog that acts as a vitamin D receptor activator (VDRA).
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Vitamin D receptor agonist
Note	卖完停产，不再备货

Associated Targets

BRD4 Tchem Bromodomain-containing protein 4 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CDK2 Tchem Cyclin-dependent kinase 2 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VDR Tclin Vitamin D3 receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FGFR3 Tclin Fibroblast growth factor receptor 3 0 Activities

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CSNK1D Tchem Casein kinase I isoform delta 0 Activities

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TRIM24 Tchem Transcription intermediary factor 1-alpha 0 Activities

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BRPF1 Tchem Peregrin 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AURKA Tchem Aurora kinase A 0 Activities

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

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ABL1 Tclin Tyrosine-protein kinase ABL1 0 Activities

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GSK3B Tclin Glycogen synthase kinase-3 beta 0 Activities

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MAPK1 Tchem Mitogen-activated protein kinase 1 0 Activities

Discover Target: MAPK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
INCHI	InChI=1S/C28H44O2/c1-18(2)19(3)9-10-20(4)25-13-14-26-22(8-7-15-28(25,26)6)11-12-23-16-24(29)17-27(30)21(23)5/h9-12,18-20,24-27,29-30H,5,7-8,13-17H2,1-4,6H3/b10-9+,22-11+,23-12-/t19-,20+,24+,25+,26-,27-,28+/m0/s1
InChi Key	HKXBNHCUPKIYDM-CGMHZMFXSA-N
Canonical SMILES	CC(C)C(C)C=CC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
Isomeric SMILES	C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C
WGK Germany	3
PubChem CID	5281107
Molecular Weight	412.65

PubChem CID

Wikipedia

CAS Registry No.

ChEMBL Ligand

ChEBI

RCSB PDB Ligand

DrugCentral Ligand

Certificates

Certificate of Analysis(COA)

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3 results found

Lot Number	Certificate Type	Date	Item
F1503057	Certificate of Analysis	Feb 13, 2023	D120130
C2205463	Certificate of Analysis	Mar 12, 2022	D120130
C2205470	Certificate of Analysis	Mar 12, 2022	D120130

Solubility

Solvent:ethanol, Max Conc. mg/mL: 20.63, Max Conc. mM: 50; Solvent:DMSO, Max Conc. mg/mL: 4.13, Max Conc. mM: 10

Sensitivity

Heat Sensitive

Melt Point(°C)

140 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS06
Signal	Danger
Hazard Statements	H300:Fatal if swallowed
Precautionary Statements	P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately.
WGK Germany	3
Merck Index	3436

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