Basic Description

Synonyms	Doxivetin \| 4-Epioxytetracycline, 6-deoxy- \| Vibramycin \| Deoxymykoin \| DMSC (Fosfatex) \| DTXSID80992212 \| FT-0625447 \| KBioSS_001287 \| SCHEMBL21753474 \| Vibramycin (monohydrate) \| (4S,4aR,5S,5aR,6R,12aS)-4-(DiMethylaMino)-3,5,10,12,12a-pentahydroxy-6-M
Specifications & Purity	Moligand™, ≥97%
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of MMP7;Inhibitor of MMP8
Note	卖完停产，不再备货
Product Description	Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor

Associated Targets(Human)

MMP7 Tchem Matrilysin (1 Activities)

Discover Target: MMP7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MMP8 Tchem Neutrophil collagenase (1 Activities)

Discover Target: MMP8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488201680
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488201680
IUPAC Name	(4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
INCHI	InChI=1S/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25-27,30,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1
InChi Key	SGKRLCUYIXIAHR-AKNGSSGZSA-N
Canonical SMILES	CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O
Isomeric SMILES	C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O
PubChem CID	54671203
Molecular Weight	444.44

Database links

ChEMBL Ligand	CHEMBL1433
PubChem CID	54671203
DrugBank Ligand	DB00254
ChEBI	CHEBI:50845
CAS Registry No.	564-25-0
Wikipedia	Doxycycline
RCSB PDB Ligand	DXT
Antibiotic DB	2011
PubChem SID	488201680

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
E2317511	Certificate of Analysis	Mar 02, 2023	D304007
E2317513	Certificate of Analysis	Mar 02, 2023	D304007
E2317531	Certificate of Analysis	Mar 02, 2023	D304007
E2317546	Certificate of Analysis	Mar 02, 2023	D304007
B2322133	Certificate of Analysis	Mar 02, 2023	D304007
B2322134	Certificate of Analysis	Mar 02, 2023	D304007
B2322135	Certificate of Analysis	Mar 02, 2023	D304007

Chemical and Physical Properties

Sensitivity	light sensitive；heat sensitive；moisture sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS09, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H411:Toxic to aquatic life with long lasting effects H302:Harmful if swallowed H400:Very toxic to aquatic life H360:May damage fertility or the unborn child
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.

Alternative Products

FAQs and Articles

FAQ

Antibiotics block bacterial protein synthesis

Categories: Technical articles

Tags:

Antibiotics Tetra Aminoglycosides Macrolides Peptidyl transferase inhibitors Antibiotics for cell culture

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Li Wang, Ya Jiao, Kaixin Zhao, Guohao Cheng, Lin Liu, Yongli Liu, Guifen Zhu. (2024) A novel carbonized polymer dots-based molecularly imprinted polymer with superior affinity and selectivity for oxytetracycline removal. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 656 (22): (332). [PMID:37995403] [10.1016/j.jcis.2023.11.115]
2. Lingling Rong, Ligui Wu, Tiao Zhang, Cui Hu, Haihui Tang, Hongcheng Pan, Xiaoming Zou. (2024) Significant Differences in the Effects of Nitrogen Doping on Pristine Biochar and Graphene-like Biochar for the Adsorption of Tetracycline. MOLECULES, 29 (1): (173). [PMID:38202756] [10.3390/molecules29010173]
3. Fredrick Gudda, Emmanuel Stephen Odinga, Lei Tang, Michael Gatheru Waigi, Jian Wang, Dyaaaldin Abdalmegeed, Yanzheng Gao. (2023) Tetracyclines uptake from irrigation water by vegetables: Accumulation and antimicrobial resistance risks. ENVIRONMENTAL POLLUTION, 338 (122696). [PMID:37804902] [10.1016/j.envpol.2023.122696]
4. Tingxia Li, Zhongxiu Chen, Zhongshuai Zhao, Zhongde Liu. (2023) A portable test strip fabricated of luminescence lanthanide-functionalized metal-organic frameworks for rapid and visual detection of tetracycline antibiotics. Analytical Methods, [PMID:37642116] [10.1039/D3AY01169K]
5. Jianan Qu, Xiaoqing Wang, Yang Zhang, Ruowen Hu, Yunqi Hao, Xuechen Zhao, Chunhui Dong, Chengxi Yang, Weirong Zhang, Jingchao Sui, Yan Huang, Peng Liu, Jian Yu, Xiaofang Chen, Yubo Fan. (2023) Cell reprogramming in a predictable manner on the superhydrophobic microwell array chip. BIOMATERIALS, 301 (122215). [PMID:37406601] [10.1016/j.biomaterials.2023.122215]
6. Jie Zhao, Qiang Song, Qiang He. (2023) Efficient removal of doxycycline by MnNb2O6/sulfite process: Response surface methodology optimization and mechanism analysis. Journal of Environmental Chemical Engineering, 11 (110383). [PMID:] [10.1016/j.jece.2023.110383]
7. Hangli Zhang, Shujuan Wang, Ji Shu, Hongyu Wang. (2023) Enhanced Removal of Doxycycline by Simultaneous Potassium Ferrate(VI) and Montmorillonite: Reaction Mechanism and Synergistic Effect. Water, 15 (9): (1758). [PMID:] [10.3390/w15091758]
8. Yining Chang, Ran He, Yanli Wei, Li Wang. (2023) Polyethyleneimine-Sulfur Quantum Dot Composites for Dual-Channel Detection of Tetracycline by Colorimetric and Fluorescence Sensing. ACS Applied Nano Materials, 6 (9): (7414–7421). [PMID:] [10.1021/acsanm.3c00506]
9. Jiameng Liu, Mengfei Wang, Chuanpan Guo, Zheng Tao, Minghua Wang, Linghao He, Baozhong Liu, Zhihong Zhang. (2023) Defective porphyrin-based metal-organic framework nanosheets derived from V2CTx MXene as a robust bioplatform for impedimetric aptasensing 17β-estradiol. FOOD CHEMISTRY, 416 (135839). [PMID:36893636] [10.1016/j.foodchem.2023.135839]
10. Wen-Ting Li, Jia-Si Wang, Meili Pang, Yue Li, Wen-Juan Ruan. (2023) Fluorescent sensor array for tetracyclines discrimination using a single Dye@MOF composite sensor. SENSORS AND ACTUATORS B-CHEMICAL, 381 (133375). [PMID:] [10.1016/j.snb.2023.133375]
11. Lin Li, Sijia Zhang, Yingying Li, Ting Wang, Xiaohong Hou. (2023) Hierarchically porous zeolitic imidazole framework-8/cellulose membrane installed in filter as sorbent for microextraction in packed syringe towards trace tetracyclines in water samples. NEW JOURNAL OF CHEMISTRY, 47 (8): (4068-4073). [PMID:] [10.1039/D2NJ05130C]
12. Tang Jiaming, Zheng Xiaoling, Jiang Shuang, Cao Mingdong, Wang Sixian, Zhou Zhaoyang, Nie Xunqing, Fang Yu, Le Tao. (2022) Dual fluorescent aptasensor for simultanous and quantitative detection of sulfadimethoxine and oxytetracycin residues in animal-derived foods tissues based on mesoporous silica. Frontiers in Nutrition, 9 [PMID:36618689] [10.3389/fnut.2022.1077893]
13. Mengdie Xu, Jia Wei, Xueru Cui, Jiamei Li, Guoping Pan, Yanan Li, Zijian Jiang, Xiruo Niu, Nan Cui, Jun Li. (2023) High-efficiency electro-Fenton process based on in-situ grown CoFeCe-LDH@CFs free-standing cathodes: Correlation of cerium and oxygen vacancies with H2O2. CHEMICAL ENGINEERING JOURNAL, 455 (140922). [PMID:] [10.1016/j.cej.2022.140922]
14. Xinyi Liao, Chen Chen, Zhijie Liang, Zhiwei Zhao, Fuyi Cui. (2023) Selective adsorption of antibiotics on manganese oxide-loaded biochar and mechanism based on quantitative structure–property relationship model. BIORESOURCE TECHNOLOGY, 367 (128262). [PMID:36343776] [10.1016/j.biortech.2022.128262]
15. Hongxia Chen, Junyu Chen, Chao Yuan, Long Yu, Mingtai Sun, Dejian Huang, Shaoquan Liu, Suhua Wang. (2023) Metal-organic frameworks-based broad-spectrum sensor for total tetracycline antibiotics assay. DYES AND PIGMENTS, 208 (110887). [PMID:] [10.1016/j.dyepig.2022.110887]
16. Cheng He, Jiaxin Ma, Huan Xu, Changzi Ge, Ziru Lian. (2022) Selective capture and determination of doxycycline in marine sediments by using magnetic imprinting dispersive solid-phase extraction coupled with high performance liquid chromatography. MARINE POLLUTION BULLETIN, 184 (114215). [PMID:36307947] [10.1016/j.marpolbul.2022.114215]
17. Bu Yiming, Yin Ranhao, Yu Long, Su Pengchen, Li Zibiao, Ye Enyi, Loh Xian Jun, Zhu Houjuan, Wang Suhua. (2022) Paper-based device for the selective determination of doxycycline antibiotic based on the turn-on fluorescence of bovine serum albumin–coated copper nanoclusters. MICROCHIMICA ACTA, 189 (11): (1-10). [PMID:36217040] [10.1007/s00604-022-05509-w]
18. Zhengzheng Zhao, Zhifang Wu, Xueling Lin, Fangjie Han, Zhishan Liang, Likun Huang, Mengjiao Dai, Dongxue Han, Lipeng Han, Li Niu. (2023) A label-free PEC aptasensor platform based on g-C3N4/BiVO4 heterojunction for tetracycline detection in food analysis. FOOD CHEMISTRY, 402 (134258). [PMID:36174353] [10.1016/j.foodchem.2022.134258]
19. Lu Zhou, Yajie Zhang, Yong Ma. (2022) Construction of a redox-responsive drug delivery system utilizing the volume of AS1411 spatial configuration gating mesoporous silica pores. Nanoscale Advances, 4 (19): (4059-4065). [PMID:36285218] [10.1039/D2NA00446A]
20. Jiawei Huang, Yunqiu Pu, Kai Xu, Qin Ding, Rongli Sun, Lihong Yin, Juan Zhang, Yuepu Pu. (2022) High expression of HIF-1α alleviates benzene-induced hematopoietic toxicity and immunosuppression in mice. ENVIRONMENTAL POLLUTION, 311 (119928). [PMID:35970343] [10.1016/j.envpol.2022.119928]
21. Yi-Fan Wang, Zhi Li, Ming Jiang, Xu Yu, Li Xu. (2022) “Two-in-one” sulfur and nitrogen co-doped fluorescent silicon nanoparticles: Simultaneous as the fluorescent probe and photocatalyst for in-situ real time visual monitoring and degradation of tetracycline antibiotics. SCIENCE OF THE TOTAL ENVIRONMENT, 846 (157470). [PMID:35868392] [10.1016/j.scitotenv.2022.157470]
22. Zehua Han, Minjie Gao, Zhihua Wang, Lichao Peng, Yanbao Zhao, Lei Sun. (2022) pH/NIR-responsive nanocarriers based on mesoporous polydopamine encapsulated gold nanorods for drug delivery and thermo-chemotherapy. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 75 (103610). [PMID:] [10.1016/j.jddst.2022.103610]
23. Kairong Yang, Pei Jia, Jinjie Hou, Shuang Zhao, Li Wang. (2022) An ingenious turn-on ratiometric fluorescence sensor for sensitive and visual detection of tetracyclines. FOOD CHEMISTRY, 396 (133693). [PMID:35868283] [10.1016/j.foodchem.2022.133693]
24. Ruihong Yao, Zhijian Li, Panpan Huo, Congcong Gong, Gang Liu, Chunhong Zheng, Shouzhi Pu. (2022) L-histidine functionalized ZiF-8 with aggregation-induced emission for detection of tetracycline. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 280 (121546). [PMID:35759934] [10.1016/j.saa.2022.121546]
25. Lishan Zhang, Zujie Yao, Huamei Tang, Qingli Song, Huanhuan Song, Jindong Yao, Zhen Li, Xiaofang Xie, Yuexu Lin, Xiangmin Lin. (2022) The Lysine Acetylation Modification in the Porin Aha1 of Aeromonas hydrophila Regulates the Uptake of Multidrug Antibiotics. MOLECULAR & CELLULAR PROTEOMICS, 21 (9): [PMID:35605723] [10.1016/j.mcpro.2022.100248]
26. Xiao Wei, Shen Zhang, Tong Wang, Aixia Chen, Jifeng Guo, Bo Bai, Shengke Yang, Yaqian Li, Xinyi Wang, Xinni Liu. (2022) Molecularly imprinted CsPbBr3 quantum dot-based fluorescent sensor for trace tetracycline detection in aqueous environments. Journal of Materials Chemistry C, 10 (21): (8432-8440). [PMID:] [10.1039/D2TC00558A]
27. Guiqiu Li, Ying Wei, Yan Guo, Hui Gong, Jie Lian, Guangjian Xu, Bing Bai, Zhijian Yu, Qiwen Deng. (2022) Omadacycline Efficacy against Streptococcus Agalactiae Isolated in China: Correlation between Resistance and Virulence Gene and Biofilm Formation. Computational Intelligence and Neuroscience, 2022 (7636983). [PMID:35510054] [10.1155/2022/7636983]
28. Shujuan Ouyang, Youqun Tang, Yanming Cao. (2022) A Novel Nanomedicine System TAR-AuNSs/Dox for the Treatment of Drug-Resistant Lymphoma. Journal of Nanomaterials, 2022 (5084672). [PMID:] [10.1155/2022/5084672]
29. Lv Yuxiong, Sun Yingying, Liu Wenjie, Yu Jianna, Jing Guoxing, Liu Wen, Xia Huaiyue, Li Dongyan, Li Wenshan. (2022) Enzyme-free dual-amplification assay for colorimetric detection of tetracycline based on Mg2+-dependent DNAzyme assisted catalytic hairpin assembly. TALANTA, 241 (123214). [PMID:35093773] [10.1016/j.talanta.2022.123214]
30. Ding Jiang, Yude Zhang, Xiaojiao Du, Youhua Tan, Wen Chen, Mo Yang. (2022) Wavelength-regulated switchable photoelectrochemical system for concurrent detection of dual antibiotics. BIOSENSORS & BIOELECTRONICS, 202 (113999). [PMID:35065476] [10.1016/j.bios.2022.113999]
31. Xuelian Hu, Ying Guo, Jinni Zhang, Xiaohui Wang, Guozhen Fang, Shuo Wang. (2022) A signal-amplified ratiometric fluorescence biomimetic sensor based on the synergistic effect of IFE and AE for the visual smart monitoring of oxytetracycline. CHEMICAL ENGINEERING JOURNAL, 433 (134499). [PMID:] [10.1016/j.cej.2022.134499]
32. Xin Wang, Longwen Li, Hong Jiang, Hui Zhangsun, Qinzhi Wang, Xinyu Sun, Li Wang. (2022) Highly selective and sensitive fluorescence detection of tetracyclines based on novel tungsten oxide quantum dots. FOOD CHEMISTRY, 374 (131774). [PMID:34896945] [10.1016/j.foodchem.2021.131774]
33. Xuewen Luo, Yujie You, Mingjun Zhong, Lin Zhao, Yingying Liu, Rongliang Qiu, Zhujian Huang. (2022) Green synthesis of manganese–cobalt–tungsten composite oxides for degradation of doxycycline via efficient activation of peroxymonosulfate. JOURNAL OF HAZARDOUS MATERIALS, 426 (127803). [PMID:34862104] [10.1016/j.jhazmat.2021.127803]
34. Ying Zhang, Yuhan Ning, Wanliang Liao, Weiping Wang, Ai-Jun Wang. (2021) Covalent organic framework-LZU1@PEI@Fe3O4-based magnetic dispersive micro-solid phase extraction of tetracyclines from environmental water prior to HPLC analysis. Analytical Methods, 13 (37): (4320-4327). [PMID:34477188] [10.1039/D1AY00873K]
35. Yinyin Chen, Xini Wang, Changfang Lu, Wei Wu, Xianxiang Wang. (2021) A ratiometric fluorometric probe for doxycycline in food by using bovine serum albumin protected Au nanoclusters. FOOD CONTROL, 129 (108218). [PMID:] [10.1016/j.foodcont.2021.108218]
36. Jin Xu, Taiping Qing, Zixin Jiang, Peng Zhang, Bo Feng. (2021) Graphene oxide-regulated low-background aptasensor for the “turn on” detection of tetracycline. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 260 (119898). [PMID:33993024] [10.1016/j.saa.2021.119898]
37. Jinghua Yu, Huan Liu, Yatao Wang, Jianhua Li, Dezhen Wu, Xiaodong Wang. (2021) Fluorescent sensing system based on molecularly imprinted phase-change microcapsules and carbon quantum dots for high-efficient detection of tetracycline. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 599 (332). [PMID:33957426] [10.1016/j.jcis.2021.04.094]
38. Yarong Wang, Xueling Yan, Qiming Kou, Qi Sun, Yuexin Wang, Ping Wu, Lulan Yang, Jiaming Tang, Tao Le. (2021) An Ultrasensitive Label-Free Fluorescent Aptasensor Platform for Detection of Sulfamethazine. International Journal of Nanomedicine, [PMID:33859476] [10.2147/IJN.S307080]
39. Yuerui Zhuang, Bixia Lin, Ying Yu, Yumin Wang, Li Zhang, Yujuan Cao, Manli Guo. (2021) A ratiometric fluorescent probe based on sulfur quantum dots and calcium ion for sensitive and visual detection of doxycycline in food. FOOD CHEMISTRY, 356 (129720). [PMID:33831834] [10.1016/j.foodchem.2021.129720]
40. Wen Zewen, Shang Yongpeng, Xu Guangjian, Pu Zhangya, Lin Zhiwei, Bai Bing, Chen Zhong, Zheng Jinxin, Deng Qiwen, Yu Zhijian. (2020) Mechanism of Eravacycline Resistance in Clinical Enterococcus faecalis Isolates From China. Frontiers in Microbiology, 11 [PMID:32523563] [10.3389/fmicb.2020.00916]
41. Shuai Han, Liang Yang, Zhigang Wen, Suyun Chu, Mei Wang, Zhenyang Wang, Changlong Jiang. (2020) A dual-response ratiometric fluorescent sensor by europium-doped CdTe quantum dots for visual and colorimetric detection of tetracycline. JOURNAL OF HAZARDOUS MATERIALS, 398 (122894). [PMID:32768819] [10.1016/j.jhazmat.2020.122894]
42. Zhan Wenhua, Li Hanrui, Guo Yingying, Du Getao, Wu Yayan, Zhang Dexin. (2020) Construction of Biocompatible Dual-Drug Loaded Complicated Nanoparticles for in vivo Improvement of Synergistic Chemotherapy in Esophageal Cancer. Frontiers in Oncology, 10 [PMID:32432038] [10.3389/fonc.2020.00622]
43. Xueming Dang, Zhilian Song, Huimin Zhao. (2020) Signal amplified photoelectrochemical assay based on Polypyrrole/g-C3N4/WO3 inverse opal photonic crystals triple heterojunction assembled through sandwich-type recognition model. SENSORS AND ACTUATORS B-CHEMICAL, 310 (127888). [PMID:] [10.1016/j.snb.2020.127888]
44. Hui-Min Lei, Ke-Ren Zhang, Cong Hui Wang, Yang Wang, Guang-Lei Zhuang, Li-Ming Lu, Jian Zhang, Ying Shen, Hong-Zhuan Chen, Liang Zhu. (2019) Aldehyde dehydrogenase 1A1 confers erlotinib resistance via facilitating the reactive oxygen species-reactive carbonyl species metabolic pathway in lung adenocarcinomas. Theranostics, 9 (24): ( 7122–7139). [PMID:31695757] [10.7150/thno.35729]
45. Zhipeng Zhang, Yao Tian, Pengcheng Huang, Fang-Ying Wu. (2020) Using target-specific aptamers to enhance the peroxidase-like activity of gold nanoclusters for colorimetric detection of tetracycline antibiotics. TALANTA, 208 (120342). [PMID:31816712] [10.1016/j.talanta.2019.120342]
46. Lin Bixia, Zhang Tingyun, Xin Xiaolan, Wu Duo, Huang Yan, Liu Yawen, Cao Yujuan, Guo Manli, Yu Ying. (2019) Europium(III) modified silicone nanoparticles for ultrasensitive visual determination of tetracyclines by employing a fluorescence color switch. MICROCHIMICA ACTA, 186 (7): (1-10). [PMID:31197467] [10.1007/s00604-019-3557-8]
47. Xueming Dang, Xiufang Zhang, Huimin Zhao. (2019) Signal amplified photoelectrochemical sensing platform with g-C3N4/inverse opal photonic crystal WO3 heterojunction electrode. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 840 (101). [PMID:] [10.1016/j.jelechem.2019.03.062]
48. Chunhua Li, Li Zhu, Weixia Yang, Xie He, Sheliang Zhao, Xiaoshuo Zhang, Wenzhi Tang, Jianlong Wang, Tianli Yue, Zhonghong Li. (2019) Amino-Functionalized Al–MOF for Fluorescent Detection of Tetracyclines in Milk. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (4): (1277–1283). [PMID:30640455] [10.1021/acs.jafc.8b06253]
49. Xin Gong, Xiao Li, Taiping Qing, Peng Zhang, Bo Feng. (2019) Amplified colorimetric detection of tetracycline based on an enzyme-linked aptamer assay with multivalent HRP-mimicking DNAzyme. ANALYST, 144 (6): (1948-1954). [PMID:30694262] [10.1039/C8AN02284D]
50. Shi Hui, Bai Cuihua, Luo Donglin, Wang Wei, Zhou Changmin, Meharg Andrew A., Yao Lixian. (2019) Degradation of tetracyclines in manure-amended soil and their uptake by litchi (Litchi chinensis Sonn.). ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 26 (6): (6209-6215). [PMID:30617894] [10.1007/s11356-018-04077-y]
51. Sihua Qian, Li’na Qiao, Wenxiang Xu, Kai Jiang, Yuhui Wang, Hengwei Lin. (2019) An inner filter effect-based near-infrared probe for the ultrasensitive detection of tetracyclines and quinolones. TALANTA, 194 (598). [PMID:30609578] [10.1016/j.talanta.2018.10.097]
52. Xiaoqiang Liu, Peipei Liu, Yunfei Tang, Liwei Yang, Lele Li, Zhichong Qi, Deliang Li, Danny K.Y. Wong. (2018) A photoelectrochemical aptasensor based on a 3D flower-like TiO2-MoS2-gold nanoparticle heterostructure for detection of kanamycin. BIOSENSORS & BIOELECTRONICS, 112 (193). [PMID:29705617] [10.1016/j.bios.2018.04.041]
53. Ting Li, Qingwen Zeng, Xingming Chen, Guojiang Wang, Haiqing Zhang, Aihua Yu, Hairui Wang, Yang Hu. (2018) The therapeutic effect of artesunate on rosacea through the inhibition of the JAK/STAT signaling pathway. Molecular Medicine Reports, 17 (6): (8385-8390). [PMID:29693177] [10.3892/mmr.2018.8887]
54. Li'na Qiao, Sihua Qian, Yuhui Wang, Shifeng Yan, Hengwei Lin. (2018) Carbon-Dots-Based Lab-On-a-Nanoparticle Approach for the Detection and Differentiation of Antibiotics. CHEMISTRY-A EUROPEAN JOURNAL, 24 (18): (4703-4709). [PMID:29369443] [10.1002/chem.201706056]
55. Yuan Xu, Yuhai Tang, Yayun Zhao, Ruixia Gao, Junjie Zhang, Delai Fu, Zhaolun Li, Hecheng Li, Xiaoshuang Tang. (2018) Bifunctional monomer magnetic imprinted nanomaterials for selective separation of tetracyclines directly from milk samples. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 515 (18). [PMID:29324271] [10.1016/j.jcis.2018.01.001]
56. Le Shang, Qiu-yue Wang, Kang-long Chen, Jing Qu, Qing-han Zhou, Jian-bin Luo, Juan Lin. (2017) SPIONs/DOX loaded polymer nanoparticles for MRI detection and efficient cell targeting drug delivery. RSC Advances, 7 (75): (47715-47725). [PMID:] [10.1039/C7RA08348C]
57. Yan-Ling Luo, Xue-Yin Zhang, Jing-Yu Fu, Feng Xu, Ya-Shao Chen. (2017) Novel temperature and pH dual-sensitive PNIPAM/CMCS/MWCNT semi-IPN nanohybrid hydrogels: Synthesis, characterization, and DOX drug release. International Journal of Polymeric Materials and Polymeric Biomaterials, [PMID:] [10.1080/00914037.2016.1233418]
58. Fang Yuan, Huimin Zhao, Xiaodan Wang, Xie Quan. (2017) Determination of Oxytetracycline by a Graphene—Gold Nanoparticle-Based Colorimetric Aptamer Sensor. ANALYTICAL LETTERS, 50 (3): (544-553). [PMID:] [10.1080/00032719.2016.1187160]
59. Fang Yuan, Huimin Zhao, Hongmei Zang, Fei Ye, Xie Quan. (2016) Three-Dimensional Graphene Supported Bimetallic Nanocomposites with DNA Regulated-Flexibly Switchable Peroxidase-Like Activity. ACS Applied Materials & Interfaces, 8 (15): (9855–9864). [PMID:27018504] [10.1021/acsami.6b00306]
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SKU	Size	Availability	Price
D304007-20mg	20mg	In stock	$31.90
D304007-100mg	100mg	In stock	$129.90
D304007-500mg	500mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$206.90

Doxycycline - 97%, high purity , CAS No.564-25-0, Inhibitor of MMP7;Inhibitor of MMP8