Basic Description

Synonyms	(acetoxymethyl-dihydroxy-tetramethyl-oxo-[?]yl) 2-phenylacetate \| CCG-208193 \| [(1R,2S,6R,10S,11R,13S,15R)-8-(acetyloxymethyl)-1,6-dihydroxy-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] 2-phenylacetate \| DOPPA \| NCGC0
Specifications & Purity	≥99%
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Product Description	12-Deoxyphorbol 13-phenylacate 20-acetates specifically activates PKC β. More potent for the β isozyme than for the α, γ, δ, or ε

Product Properties

pKa	pKa: 11.31 (Predicted)

Associated Targets(Human)

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)

Discover Target: GBA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

BCHE Cholinesterase (8742 Activities)

Discover Target: BCHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	[(1R,2S,6R,10S,11R,13S,15R)-8-(acetyloxymethyl)-1,6-dihydroxy-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] 2-phenylacetate
INCHI	InChI=1S/C30H36O7/c1-17-11-23-28(34,26(17)33)15-21(16-36-19(3)31)12-22-25-27(4,5)29(25,14-18(2)30(22,23)35)37-24(32)13-20-9-7-6-8-10-20/h6-12,18,22-23,25,34-35H,13-16H2,1-5H3/t18-,22+,23-,25-,28-,29+,30-/m1/s1
InChi Key	MEDVHSNRBPAIPU-XMOZQXTISA-N
Canonical SMILES	CC1CC2(C(C2(C)C)C3C1(C4C=C(C(=O)C4(CC(=C3)COC(=O)C)O)C)O)OC(=O)CC5=CC=CC=C5
Isomeric SMILES	C[C@@H]1C[C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@]4(CC(=C3)COC(=O)C)O)C)O)OC(=O)CC5=CC=CC=C5
WGK Germany	3
PubChem CID	3034821
Molecular Weight	508.6

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Solubility	Soluble in ethanol, and DMSO (≥5 mg/ml).
Refractive Index	n20D1.61 (Predicted)
Boil Point(°C)	~635.67° C at 760 mmHg (Predicted)

Safety and Hazards(GHS)

WGK Germany	3

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Bin Li, Ling Wang. (2023) Effects of polycarboxylate superplasticizer equipped with β-cyclodextrin as the terminal group on the fluidity of montmorillonite-containing cement paste. JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, [PMID:] [10.1080/01932691.2022.2042309]
2. Xiaojing Su, Shengqi Huang, Wenjian Wu, Kunquan Li, Huali Xie, Yunhui Wu, Xiaofan Zhang, Xin Xie. (2022) Protonated cross-linkable nanocomposite coatings with outstanding underwater superoleophobic and anti-viscous oil-fouling properties for crude oil/water separation. JOURNAL OF HAZARDOUS MATERIALS, 436 (129129). [PMID:35584584] [10.1016/j.jhazmat.2022.129129]
3. Wang Chenhui, Han Dengbao, Wang Junhui, Yang Yingguo, Liu Xinyue, Huang Sheng, Zhang Xin, Chang Shuai, Wu Kaifeng, Zhong Haizheng. (2020) Dimension control of in situ fabricated CsPbClBr2 nanocrystal films toward efficient blue light-emitting diodes. Nature Communications, 11 (1): (1-8). [PMID:33353939] [10.1038/s41467-020-20163-7]

References

1. Bin Li, Ling Wang. (2023) Effects of polycarboxylate superplasticizer equipped with β-cyclodextrin as the terminal group on the fluidity of montmorillonite-containing cement paste. JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, [PMID:] [10.1080/01932691.2022.2042309]
2. Xiaojing Su, Shengqi Huang, Wenjian Wu, Kunquan Li, Huali Xie, Yunhui Wu, Xiaofan Zhang, Xin Xie. (2022) Protonated cross-linkable nanocomposite coatings with outstanding underwater superoleophobic and anti-viscous oil-fouling properties for crude oil/water separation. JOURNAL OF HAZARDOUS MATERIALS, 436 (129129). [PMID:35584584] [10.1016/j.jhazmat.2022.129129]
3. Wang Chenhui, Han Dengbao, Wang Junhui, Yang Yingguo, Liu Xinyue, Huang Sheng, Zhang Xin, Chang Shuai, Wu Kaifeng, Zhong Haizheng. (2020) Dimension control of in situ fabricated CsPbClBr2 nanocrystal films toward efficient blue light-emitting diodes. Nature Communications, 11 (1): (1-8). [PMID:33353939] [10.1038/s41467-020-20163-7]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

dPPA - 99%, high purity , CAS No.54662-30-5