DPPE Fumarate , CAS No.98774-23-3

Item Number
D350282
Grouped product items
SKUSizeAvailabilityPrice Qty
D350282-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
D350282-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$418.90

a compound that inhibits histamine binding at the intracellular histamine (Hlc) site

Basic Description

SynonymsCAS-98774-23-3 | Ethanamine, N,N-diethyl-2-(4-(phenylmethyl)phenoxy)- | N,N-Diethyl-2-((4-phenylmethyl)phenoxy)ethanamine | 2-(4-benzylphenoxy)-N,N-diethylethanamine | Hydrazine sulfate salt, p.a., ACS reagent, 99.0% | Tesmilifene | BDBM50085260 | UNII-I4
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
Product Description

DPPE Fumarate has high affinity for the anti-estrogen binding site. Inhibits histamine binding at the intracellular histamine (Hlc) site. DPPE Fumarate does not bind to the estrogen receptor.

Associated Targets(Human)

LTA4H Tchem Leukotriene A-4 hydrolase (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
LTA4H Tchem Leukotriene A4 hydrolase (1442 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EBP Tchem Anti-estrogen binding site (AEBS) (124 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTT Tchem Huntingtin (19182 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Estrogen receptor (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-(4-benzylphenoxy)-N,N-diethylethanamine
INCHI InChI=1S/C19H25NO/c1-3-20(4-2)14-15-21-19-12-10-18(11-13-19)16-17-8-6-5-7-9-17/h5-13H,3-4,14-16H2,1-2H3
InChi Key NFIXBCVWIPOYCD-UHFFFAOYSA-N
Canonical SMILES CCN(CC)CCOC1=CC=C(C=C1)CC2=CC=CC=C2
Isomeric SMILES CCN(CC)CCOC1=CC=C(C=C1)CC2=CC=CC=C2
PubChem CID 108092
Molecular Weight 399.49

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble to 100 mM in DMSO

Related Documents

Citations of This Product

1. Yi-Fan Tan, Guang-Min Liang, Kun Zhou, Jiu-Yu Ji, Li-Ping Zhao.  (2023)  Synthesis, crystal structure, characterization, effective photocurrent response and photodegradation of a silver(I) diphosphine 3D supramolecular structure.  JOURNAL OF ORGANOMETALLIC CHEMISTRY,  1001  (20): (122879).  [PMID:15990874] [10.1016/j.jorganchem.2023.122879]
2. Zhichao Yu, Hexiang Gong, Meijin Li, Dianping Tang.  (2022)  Hollow prussian blue nanozyme-richened liposome for artificial neural network-assisted multimodal colorimetric-photothermal immunoassay on smartphone.  BIOSENSORS & BIOELECTRONICS,  218  (114751).  [PMID:36215735] [10.1016/j.bios.2022.114751]
3. Liu Fulei, Han Lingfei, Huang Xiaoxian, Sang Mangmang, Liu Bowen, Li Cong, Ma Congyu, Liu Wenyuan, Feng Feng, Qu Wei.  (2018)  Reticuloendothelial System Pre-Block Strategy to Improve Tumor Targeting Efficacy for Hyaluronic Acid Related Drug Delivery System.  Journal of Biomedical Nanotechnology,  14  (10): (1731-1743).  [PMID:30041720] [10.1166/jbn.2018.2603]

References

1. Yi-Fan Tan, Guang-Min Liang, Kun Zhou, Jiu-Yu Ji, Li-Ping Zhao.  (2023)  Synthesis, crystal structure, characterization, effective photocurrent response and photodegradation of a silver(I) diphosphine 3D supramolecular structure.  JOURNAL OF ORGANOMETALLIC CHEMISTRY,  1001  (20): (122879).  [PMID:15990874] [10.1016/j.jorganchem.2023.122879]
2. Zhichao Yu, Hexiang Gong, Meijin Li, Dianping Tang.  (2022)  Hollow prussian blue nanozyme-richened liposome for artificial neural network-assisted multimodal colorimetric-photothermal immunoassay on smartphone.  BIOSENSORS & BIOELECTRONICS,  218  (114751).  [PMID:36215735] [10.1016/j.bios.2022.114751]
3. Liu Fulei, Han Lingfei, Huang Xiaoxian, Sang Mangmang, Liu Bowen, Li Cong, Ma Congyu, Liu Wenyuan, Feng Feng, Qu Wei.  (2018)  Reticuloendothelial System Pre-Block Strategy to Improve Tumor Targeting Efficacy for Hyaluronic Acid Related Drug Delivery System.  Journal of Biomedical Nanotechnology,  14  (10): (1731-1743).  [PMID:30041720] [10.1166/jbn.2018.2603]

Solution Calculators