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DQP 1105 - ≥97%(HPLC), high purity , CAS No.380560-89-4, Allosteric modulator of GluN2B;Allosteric modulator of GluN2C;Allosteric modulator of GluN2D

Moligand™
≥97%(HPLC)

CAS#: 380560-89-4
Formula: C₂₉H₂₄BrN₃O₄
Molecular Weight: 558.42
PubChem CID: 2723792

Item Number

D288390

Grouped product items
SKU	Size	Availability	Price
D288390-5mg	5mg	In stock	$102.90
D288390-10mg	10mg	In stock	$177.90
D288390-25mg	25mg	In stock	$375.90
D288390-50mg	50mg	In stock	$676.90
D288390-100mg	100mg	In stock	$1,218.90

GluN2C/GluN2D-selective NMDA antagonist

View related series

GluN2B Allosteric modulator GluN2C Allosteric modulator GluN2D Allosteric modulator

Basic Description

Synonyms	1784-03-8\|Tos-Arg-OMe.HCl\|TAME hydrochloride\|TOS-ARG-OME HCL\|TAME HCl\|Nalpha-p-Tosyl-L-arginine methyl ester hydrochloride\|(S)-Methyl 5-guanidino-2-(4-methylphenylsulfonamido)pentanoate hydrochloride\|Nalpha-Tosyl-L-arginine Methyl Ester Hydrochloride\|meth
Specifications & Purity	≥97%(HPLC)
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	ALLOSTERIC MODULATOR
Mechanism of action	Allosteric modulator of GluN2B;Allosteric modulator of GluN2C;Allosteric modulator of GluN2D

Associated Targets

GRIN2B Tclin Glutamate receptor ionotropic, NMDA 2B 1 Activities

Discover Target: GRIN2B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN2C Tclin Glutamate receptor ionotropic, NMDA 2C 1 Activities

Discover Target: GRIN2C

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN2D Tclin Glutamate receptor ionotropic, NMDA 2D 1 Activities

Discover Target: GRIN2D

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

InChi Key

JIQFFACVQXXHMY-YDALLXLXSA-N

Canonical SMILES

O=C2C(C4=NN(C(CCC(O)=O)=O)C(C5=CC=C(Br)C=C5)C4)=C(C3=CC=CC=C3)C1=CC(C)=CC=C1N2

Isomeric SMILES

CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CCCN=C(N)N)C(=O)OC.Cl

PubChem CID

2723792

Molecular Weight

558.42

PubChem CID

76849261

CAS Registry No.

380560-89-4

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
G2213249	Certificate of Analysis	Jun 08, 2022	D288390
G2213251	Certificate of Analysis	Jun 08, 2022	D288390
G2213252	Certificate of Analysis	Jun 08, 2022	D288390
G2213253	Certificate of Analysis	Jun 08, 2022	D288390
G2213254	Certificate of Analysis	Jun 08, 2022	D288390

References

1. Acker TM, Yuan H, Hansen KB, Vance KM, Ogden KK, Jensen HS, Burger PB, Mullasseril P, Snyder JP, Liotta DC et al.. (2011) Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators.. Mol Pharmacol, 80 (5): (782-95). [PMID:21807990]

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