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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D609980-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $139.90 | |
D609980-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,400.90 | |
D609980-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $799.90 | |
D609980-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,000.90 |
Synonyms | DS-3801B free base | DS-3801b | 5H2DV04I6O | 1369412-66-7 | CHEMBL5201797 | DS-3801A | Cyclohexanecarboxamide, 4-(3-(hydroxymethyl)phenoxy)-N-methyl-N-(3-methyl-4-(((3S)-3-methyl-1-piperazinyl)methyl)phenyl)-, trans- | DS-3801bfree | DS-3801b free | UNII-5H2DV04I6O | SCHEMBL |
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Specifications & Purity | Moligand™, ≥98% |
Storage Temp | Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of motilin receptor |
Product Description | DS-3801b is a potent and non-macrolide agonist of GPR38. DS-3801b is expected to be novel gastrointestinal prokinetic agents for the research of functional gastrointestinal disorders such as gastroparesis and chronic constipation. |
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Canonical SMILES | C[C@H]1CN(CCN1)CC2=C(C=C(C=C2)N(C)C(=O)C3CCC(CC3)OC4=CC=CC(=C4)CO)C |
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Isomeric SMILES | C[C@H]1CN(CCN1)CC2=C(C=C(C=C2)N(C)C(=O)C3CCC(CC3)OC4=CC=CC(=C4)CO)C |
PubChem CID | 56960876 |
Molecular Weight | 465.63 |
GPCRdb Ligand | DS-3801b free base |
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PubChem CID | 56960876 |
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Sensitivity | Moisture sensitive |
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1. Toda N, Shida T, Takano R, Katagiri T, Hirouchi M, Abe M, Soma K, Nakagami Y, Yamazaki M. (2022) Discovery of DS-3801b, a non-macrolide GPR38 agonist with N-methylanilide structure.. Bioorg Med Chem Lett, 59 (3): (128554). [PMID:35051575] |