JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

DX-2507, Antibody of Fc fragment of IgG receptor and transporter

Features and benefits

Item Number

Ab175515

Grouped product items
SKU	Size	Availability	Price	Qty
Ab175515-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,668.90
Ab175515-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$4,668.90

View related series

Basic Description

Product Name	DX-2507
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ANTIBODY
Mechanism of action	Antibody of Fc fragment of IgG receptor and transporter

CAS	Ab175515

FCGRT Tclin IgG receptor FcRn large subunit p51 (0 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Enter Lot Number to search for COA:

1. Nixon AE, Chen J, Sexton DJ, Muruganandam A, Bitonti AJ, Dumont J, Viswanathan M, Martik D, Wassaf D, Mezo A et al.. (2015) Fully human monoclonal antibody inhibitors of the neonatal fc receptor reduce circulating IgG in non-human primates.. Front Immunol, 6 (13): (176). [PMID:25954273] [10.1021/op500134e]
2. Kenniston JA, Taylor BM, Conley GP, Cosic J, Kopacz KJ, Lindberg AP, Comeau SR, Atkins K, Bullen J, TenHoor C et al.. (2017) Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody.. J Biol Chem, 292 (42): (17449-17460). [PMID:28878017] [10.1021/op500134e]

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.