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Dynole 34-2 - 97%, high purity , CAS No.1128165-88-7

≥97%

CAS#: 1128165-88-7
Formula: C₂₅H₃₆N₄O
Molecular Weight: 408.59
PubChem CID: 44157463

Item Number

D275968

Grouped product items
SKU	Size	Availability	Price
D275968-5mg	5mg	In stock	$117.90
D275968-10mg	10mg	In stock	$197.90
D275968-25mg	25mg	In stock	$395.90
D275968-50mg	50mg	In stock	$632.90
D275968-100mg	100mg	In stock	$1,139.90

Potent dynamin I and dynamin II inhibitor

Synonyms

2-Cyano-N-octyl-3-[1-(3-dimethylaminopropyl)-1H-indol-3-yl]acrylamide；(Z)-2-cyano-3-(1-(3-(dimethylamino)propyl)-1H-indol-3-yl)-N-octylacrylamide

Specifications & Purity

97%

Storage Temp

Store at -20°C,Desiccated

Shipped In

Dry ice

Names and Identifiers

IUPAC Name	(E)-2-cyano-3-[1-[3-(dimethylamino)propyl]indol-3-yl]-N-octylprop-2-enamide
INCHI	InChI=1S/C25H36N4O/c1-4-5-6-7-8-11-15-27-25(30)21(19-26)18-22-20-29(17-12-16-28(2)3)24-14-10-9-13-23(22)24/h9-10,13-14,18,20H,4-8,11-12,15-17H2,1-3H3,(H,27,30)/b21-18+
InChi Key	MYIMRONQBLZJFI-DYTRJAOYSA-N
Canonical SMILES	CCCCCCCCNC(=O)C(=CC1=CN(C2=CC=CC=C21)CCCN(C)C)C#N
Isomeric SMILES	CCCCCCCCNC(=O)/C(=C/C1=CN(C2=CC=CC=C21)CCCN(C)C)/C#N
PubChem CID	44157463
Molecular Weight	408.59

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5 results found

Lot Number	Certificate Type	Date	Item
I2202499	Certificate of Analysis	Jun 13, 2023	D275968
I2202500	Certificate of Analysis	Jun 13, 2023	D275968
I2202501	Certificate of Analysis	Jun 13, 2023	D275968
I2202495	Certificate of Analysis	Jun 13, 2023	D275968
I2202244	Certificate of Analysis	Jun 12, 2023	D275968

References

1. Lynn KS et al.. (2021) Asymmetric distribution of dynamin-2 and ß-catenin relative to tight junction spikes in alveolar epithelial cells.. Tissue Barriers, (1929786). [PMID:34107845]
2. Stallaert W et al.. (2018) Contact inhibitory Eph signaling suppresses EGF-promoted cell migration by decoupling EGFR activity from vesicular recycling.. Sci Signal, 11 (541): [PMID:30065026]
3. Ivanova D et al.. (2020) CtBP1-Mediated Membrane Fission Contributes to Effective Recycling of Synaptic Vesicles.. Cell Rep, 30 (7): (2444-2459.e7). [PMID:32075774]
4. Štimac I et al.. (2021) Dynamin Inhibitors Prevent the Establishment of the Cytomegalovirus Assembly Compartment in the Early Phase of Infection.. Life (Basel), 11 (9): [PMID:34575026]
5. Eppler FJ et al.. (2017) Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion.. PLoS One, 12 (3): (e0172443). [PMID:28273099]
6. González-Jamett AM et al.. (2017) Dynamin-2 mutations linked to Centronuclear Myopathy impair actin-dependent trafficking in muscle cells.. Sci Rep, 7 (4580). [PMID:28676641]
7. Wang D et al.. (2020) ERK is involved in the differentiation and function of dimethyl sulfoxide-induced HL-60 neutrophil-like cells, which mimic inflammatory neutrophils.. Int Immunopharmacol, 84 (106510). [PMID:32361568]
8. de la Vega M et al.. (2011) Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion.. Retrovirology, 8 (99). [PMID:22145853]
9. Richard JP et al.. (2011) Intracellular curvature-generating proteins in cell-to-cell fusion.. Biochem J, 440 (2): (185-93). [PMID:21895608]
10. Szymanska E et al.. (2016) Impaired dynamin 2 function leads to increased AP-1 transcriptional activity through the JNK/c-Jun pathway.. Cell Signal, 28 (160-71). [PMID:26475677]
11. Kockx M et al.. (2014) Pharmacological inhibition of dynamin II reduces constitutive protein secretion from primary human macrophages.. PLoS One, 9 (10): (e111186). [PMID:25347775]

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Dynole 34-2 - 97%, high purity , CAS No.1128165-88-7

Basic Description