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E-4031 - ≥98%, high purity , CAS No.113559-13-0

  • ≥98%
Item Number
E275345
Grouped product items
SKUSizeAvailabilityPrice Qty
E275345-5mg
5mg
In stock
$75.90
E275345-10mg
10mg
In stock
$127.90
E275345-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$288.90
E275345-50mg
50mg
In stock
$561.90
E275345-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,011.90

Discover E-4031 by Aladdin Scientific in ≥98% for only $75.90. Available - in Ligands at Aladdin Scientific. HERG K + channel blocker Tags: .

Basic Description

Synonyms113559-13-0|E-4031 dihydrochloride|E-4031|1-(2-(6-Methyl-2-pyridyl)ethyl)-4-(4-methylsulfonylaminobenzoyl)piperidine dihydrochloride|E-4031 Free|814AT2BQO7|CHEMBL536480|N-[4-[1-[2-(6-methylpyridin-2-yl)ethyl]piperidine-4-carbonyl]phenyl]methanesulfonamide
Specifications & Purity≥98%
Storage TempStore at 2-8°C,Desiccated
Shipped InWet ice
Product Description

Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 16 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-[4-[1-[2-(6-methylpyridin-2-yl)ethyl]piperidine-4-carbonyl]phenyl]methanesulfonamide;dihydrochloride
INCHI InChI=1S/C21H27N3O3S.2ClH/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2,26)27;;/h3-9,18,23H,10-15H2,1-2H3;2*1H
InChi Key ZQBNWMFBOSOOLX-UHFFFAOYSA-N
Canonical SMILES CC1=NC(=CC=C1)CCN2CCC(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C.Cl.Cl
Isomeric SMILES CC1=NC(=CC=C1)CCN2CCC(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C.Cl.Cl
PubChem CID 3087190
Molecular Weight 474.44

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
J2127243Certificate of AnalysisAug 12, 2022 E275345
J2127245Certificate of AnalysisAug 12, 2022 E275345
J2127278Certificate of AnalysisAug 12, 2022 E275345

Chemical and Physical Properties

SolubilitySoluble in water to 100 mM

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

Related Documents

References

1. Zhang F et al..  (2022)  High-throughput optical action potential recordings in hiPSC-derived cardiomyocytes with a genetically encoded voltage indicator in the AAVS1 locus..  Front Cell Dev Biol,  10  (1038867).  [PMID:36274846]
2. Greenwood IA et al..  (2009)  Loss of functional K+ channels encoded by ether-à-go-go-related genes in mouse myometrium prior to labour onset..  J Physiol,  587  (Pt 10): (2313-26).  [PMID:19332483]
3. Fukushiro-Lopes DF et al..  (2018)  Preclinical study of a Kv11.1 potassium channel activator as antineoplastic approach for breast cancer..  Oncotarget,  (3): (3321-3337).  [PMID:29423049]

Solution Calculators