Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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I137677-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $62.90 | |
I137677-250mg | 250mg | In stock | $178.90 | |
I137677-1g | 1g | In stock | $452.90 | |
I137677-5g | 5g | In stock | $2,034.90 |
Pyrimidine nucleoside analog. Antiviral agent.
Synonyms | Brivudine | 69304-47-8 | BVDU | (E)-5-(2-Bromovinyl)-2'-deoxyuridine | Brivudin | Helpin | Zostex | Bromovinyldeoxyuridine | Brivudine [INN] | 5-BROMOVINYLDEOXYURIDINE | (E)-5-(2-Bromovinyl)-deoxyuridine | RP101 | RP-101 | DTXSID0045755 | Brivudine (INN) | NSC-633770 | 5-((E)-2-bromovin |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Pyrimidine nucleoside analog. Antiviral agent (IC 50 values are 76 nM and 1.4 μM for herpesvirus and HIV respectively). Blocks DNA polymerase. Binds to heat shock protein HSPB1 and inhibits interaction with its binding partners. Shows anticancer effects i |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Brivudine is an antiviral coumpound. |
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IUPAC Name | 5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
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INCHI | InChI=1S/C11H13BrN2O5/c12-2-1-6-4-14(11(18)13-10(6)17)9-3-7(16)8(5-15)19-9/h1-2,4,7-9,15-16H,3,5H2,(H,13,17,18)/b2-1+/t7-,8+,9+/m0/s1 |
InChi Key | ODZBBRURCPAEIQ-PIXDULNESA-N |
Canonical SMILES | C1C(C(OC1N2C=C(C(=O)NC2=O)C=CBr)CO)O |
Isomeric SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)/C=C/Br)CO)O |
WGK Germany | 3 |
RTECS | YU7355000 |
PubChem CID | 446727 |
Molecular Weight | 333.14 |
Reaxy-Rn | 758153 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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H2206424 | Certificate of Analysis | May 11, 2024 | I137677 |
H2206425 | Certificate of Analysis | May 11, 2024 | I137677 |
H2206598 | Certificate of Analysis | May 11, 2024 | I137677 |
E1611130 | Certificate of Analysis | Oct 16, 2023 | I137677 |
Solubility | Soluble in water (partly), and methanol. |
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Sensitivity | Heat Sensitive |
Specific Rotation[α] | 9° (C=1,MeOH) |
Melt Point(°C) | 166 °C(dec.) |
WGK Germany | 3 |
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RTECS | YU7355000 |
Reaxy-Rn | 758153 |
Merck Index | 1378 |