The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Ebastine - ≥99%, high purity , Histamine H1 receptor inverse agonist, CAS No.90729-43-4, Histamine H1 receptor inverse agonist
Basic Description Synonyms ebastine|90729-43-4|Kestine|Ebastel|Ebastin|Bactil|Kestin|LAS W-090|RP 64305|LAS-W-090|1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piperidin-1-yl]butan-1-one|LAS-W 090;RP64305|RP64305|4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one|4- Specifications & Purity ≥99% Storage Temp Store at 2-8°C,Protected from light Shipped In Wet ice Action Type INVERSE AGONIST Mechanism of action Histamine H1 receptor inverse agonist
Names and Identifiers IUPAC Name 4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one INCHI InChI=1S/C32H39NO2/c1-32(2,3)28-18-16-25(17-19-28)30(34)15-10-22-33-23-20-29(21-24-33)35-31(26-11-6-4-7-12-26)27-13-8-5-9-14-27/h4-9,11-14,16-19,29,31H,10,15,20-24H2,1-3H3 InChi Key MJJALKDDGIKVBE-UHFFFAOYSA-N Canonical SMILES CC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4 Isomeric SMILES CC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4 WGK Germany 3 RTECS EL8140000 PubChem CID 3191 Molecular Weight 469.66 Reaxy-Rn 7522103
Chemical and Physical Properties Solubility Slightly soluble in chloroform, methanol Sensitivity Light sensitive Melt Point(°C) 85.0-89.0 °C
Safety and Hazards(GHS) Hazard Statements H413: May cause long lasting harmful effects to aquatic life
Precautionary Statements P273: Avoid release to the environment.
P501: Dispose of contents/container to ...
WGK Germany 3 RTECS EL8140000 Reaxy-Rn 7522103
References 1. Li Q et al.. (2020) Antihistamine Drug Ebastine Inhibits Cancer Growth by Targeting Polycomb Group Protein EZH2.. Mol Cancer Ther, 19 (10): (2023-2033). [PMID:32855270 ]
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator