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Activin and Inhibin
Eggmanone - ≥98%(HPLC), high purity , CAS No.505068-32-6

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Eggmanone - ≥98%(HPLC), high purity , CAS No.505068-32-6

≥98%(HPLC)

CAS#: 505068-32-6
Formula: C₂₀H₂₀N₂O₂S₃
Molecular Weight: 416.58
PubChem CID: 1158635

Item Number

E288632

Grouped product items
SKU	Size	Availability	Price	Qty
E288632-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$139.90
E288632-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$584.90

Potent and selective PDE4 inhibitor; suppresses hedgehog signaling

Basic Description

Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Potent and selective phosphodiesterase (PDE) 4 inhibitor (IC50= 72 nM). Exhibits >40-fold selectivity over PDE3, PDE10, and PDE11. Displays no significant activity on a panel of 442 kinases, 158 GPCRs and 21 phosphatases. Suppresses hedgehog signaling thr
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D (1 Activities)

Discover Target: PDE4D

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Associated Targets(non-human)

Pde4d Phosphodiesterase 4D (4 Activities)

Discover Target: Pde4d

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	3-(2-methylprop-2-enyl)-2-(2-oxo-2-thiophen-2-ylethyl)sulfanyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one
INCHI	InChI=1S/C20H20N2O2S3/c1-12(2)10-22-19(24)17-13-6-3-4-7-15(13)27-18(17)21-20(22)26-11-14(23)16-8-5-9-25-16/h5,8-9H,1,3-4,6-7,10-11H2,2H3
InChi Key	XAKJIQPEGSCYIP-UHFFFAOYSA-N
Canonical SMILES	CC(=C)CN1C(=O)C2=C(N=C1SCC(=O)C3=CC=CS3)SC4=C2CCCC4
Isomeric SMILES	CC(=C)CN1C(=O)C2=C(N=C1SCC(=O)C3=CC=CS3)SC4=C2CCCC4
PubChem CID	1158635
Molecular Weight	416.58

Certificates

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Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 8.33, Max Conc. mM: 20

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