Eggmanone - ≥98%(HPLC), high purity , CAS No.505068-32-6

Item Number

E288632

Grouped product items
SKU	Size	Availability	Price	Qty
E288632-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$139.90
E288632-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$584.90

Potent and selective PDE4 inhibitor; suppresses hedgehog signaling

Basic Description

Synonyms	5,6,7,8-Tetrahydro-3-(2-methyl-2-propen-1-yl)-2-[[2-oxo-2-(2-thienyl)ethyl]thio]-[1]benzothieno[2,3-d]pyrimidin-4(3H)-one
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Potent and selective phosphodiesterase (PDE) 4 inhibitor (IC50= 72 nM). Exhibits >40-fold selectivity over PDE3, PDE10, and PDE11. Displays no significant activity on a panel of 442 kinases, 158 GPCRs and 21 phosphatases. Suppresses hedgehog signaling thr
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	3-(2-methylprop-2-enyl)-2-(2-oxo-2-thiophen-2-ylethyl)sulfanyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one
INCHI	InChI=1S/C20H20N2O2S3/c1-12(2)10-22-19(24)17-13-6-3-4-7-15(13)27-18(17)21-20(22)26-11-14(23)16-8-5-9-25-16/h5,8-9H,1,3-4,6-7,10-11H2,2H3
InChi Key	XAKJIQPEGSCYIP-UHFFFAOYSA-N
Canonical SMILES	CC(=C)CN1C(=O)C2=C(N=C1SCC(=O)C3=CC=CS3)SC4=C2CCCC4
Isomeric SMILES	CC(=C)CN1C(=O)C2=C(N=C1SCC(=O)C3=CC=CS3)SC4=C2CCCC4
PubChem CID	1158635
Molecular Weight	416.58

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Basic Description