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EHop-016 - ≥99%, high purity , CAS No.1380432-32-5
Basic Description Synonyms N4-(9-Ethyl-9H-carbazol-3-yl)-N2-(3-morpholin-4-yl-propyl)-pyrimidine-2,4-diamine Specifications & Purity Moligand™, ≥99% Biochemical and Physiological Mechanisms Rac inhibitor (IC50= 1.1 μM). Exhibits some selectivity for Rac1 and Rac3 over Cdc42. Blocks the interaction of Rac with guanine nucleotide exchange factor Vav2 in breast cancer cell lines expressing high levels of Rac activity and inhibits activity of R Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name 4-N-(9-ethylcarbazol-3-yl)-2-N-(3-morpholin-4-ylpropyl)pyrimidine-2,4-diamine INCHI InChI=1S/C25H30N6O/c1-2-31-22-7-4-3-6-20(22)21-18-19(8-9-23(21)31)28-24-10-12-27-25(29-24)26-11-5-13-30-14-16-32-17-15-30/h3-4,6-10,12,18H,2,5,11,13-17H2,1H3,(H2,26,27,28,29) InChi Key AFTZZRFCMOAFCR-UHFFFAOYSA-N Canonical SMILES CCN1C2=C(C=C(C=C2)NC3=NC(=NC=C3)NCCCN4CCOCC4)C5=CC=CC=C51 Isomeric SMILES CCN1C2=C(C=C(C=C2)NC3=NC(=NC=C3)NCCCN4CCOCC4)C5=CC=CC=C51 WGK Germany 3 PubChem CID 51031035 Molecular Weight 430.55
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 21.53, Max Conc. mM: 50
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H2206532