1.Grasberger BL, Lu T, Schubert C, Parks DJ, Carver TE, Koblish HK, Cummings MD, LaFrance LV, Milkiewicz KL, Calvo RR et al.. (2005) Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.. J Med Chem, 48 (4):(909-12). [PMID:15715460][10.1021/op500134e]
2.Raboisson P, Marugán JJ, Schubert C, Koblish HK, Lu T, Zhao S, Player MR, Maroney AC, Reed RL, Huebert ND et al.. (2005) Structure-based design, synthesis, and biological evaluation of novel 1,4-diazepines as HDM2 antagonists.. Bioorg Med Chem Lett, 15 (7):(1857-61). [PMID:15780621][10.1021/op500134e]
3.Antuch W, Menon S, Chen QZ, Lu Y, Sakamuri S, Beck B, Schauer-Vukasinović V, Agarwal S, Hess S, Dömling A. (2006) Design and modular parallel synthesis of a MCR derived alpha-helix mimetic protein-protein interaction inhibitor scaffold.. Bioorg Med Chem Lett, 16 (6):(1740-3). [PMID:16427279][10.1021/op500134e]
4.Cummings MD, Schubert C, Parks DJ, Calvo RR, LaFrance LV, Lattanze J, Milkiewicz KL, Lu T. (2006) Substituted 1,4-benzodiazepine-2,5-diones as alpha-helix mimetic antagonists of the HDM2-p53 protein-protein interaction.. Chem Biol Drug Des, 67 (3):(201-5). [PMID:16611213][10.1021/op500134e]
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