Grouped product items

SKU

Size

Availability

Price

Qty

E126032-5mg

5mg

Available within 4-8 weeks(?)

$64.90

E126032-25mg

25mg

Available within 4-8 weeks(?)

$292.90

E126032-100mg

100mg

Available within 4-8 weeks(?)

$380.90

Basic Description

Synonyms	STA-4783
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Elesclomol significantly induces the expression of heat shock stress response genes and metallothionein genes, a signature transcription profile indicative of oxidative stress in Hs294T cells。Elesclomol significantly inhibits the cell viability of SK-MEL-
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Note	100mg卖完停产，不再备货
Product Description	Elesclomol (STA-4783) is a novel potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells. Phase 3.

Associated Targets(Human)

5637 (630 Activities)

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A 172 (535 Activities)

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A204 (242 Activities)

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A2058 (690 Activities)

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A-375 (9258 Activities)

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A-427 (643 Activities)

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A498 (42825 Activities)

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A673 (619 Activities)

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ACHN (49357 Activities)

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AGS (1999 Activities)

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BT-20 (503 Activities)

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BT-474 (2113 Activities)

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BXPC-3 (2997 Activities)

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C8166 (1658 Activities)

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CAKI-1 (44928 Activities)

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Calu-3 (339 Activities)

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Calu-6 (398 Activities)

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CAPAN-1 (772 Activities)

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CCRF-CEM (65223 Activities)

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CFPAC-1 (421 Activities)

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COLO 205 (50209 Activities)

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COR-L23 (253 Activities)

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Daoy (570 Activities)

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DMS-79 (150 Activities)

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DMS-273 (14108 Activities)

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DU-145 (51482 Activities)

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G-361 (890 Activities)

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G-401 (156 Activities)

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HL-60 (67320 Activities)

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HT-1080 (3966 Activities)

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HT-29 (80576 Activities)

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HuCCT-1 (128 Activities)

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Huh-7 (12904 Activities)

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HuTu80 (255 Activities)

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J82 (505 Activities)

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JAR (316 Activities)

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K562 (73714 Activities)

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KM12 (47707 Activities)

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LoVo (4724 Activities)

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M14 (47487 Activities)

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MCF7 (126967 Activities)

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MDA-MB-361 (612 Activities)

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MDA-MB-453 (1139 Activities)

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MG-63 (795 Activities)

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NCI-H1975 (4994 Activities)

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MKN-1 (175 Activities)

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MKN-28 (466 Activities)

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MKN-45 (2102 Activities)

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MKN-7 (272 Activities)

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ML-2 (146 Activities)

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Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mycobacterium tuberculosis (203094 Activities)

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Canis familiaris (36305 Activities)

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Mus musculus (284745 Activities)

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Rattus norvegicus (775804 Activities)

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H4 (48 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	1-N',3-N'-bis(benzenecarbonothioyl)-1-N',3-N'-dimethylpropanedihydrazide
INCHI	InChI=1S/C19H20N4O2S2/c1-22(18(26)14-9-5-3-6-10-14)20-16(24)13-17(25)21-23(2)19(27)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3,(H,20,24)(H,21,25)
InChi Key	BKJIXTWSNXCKJH-UHFFFAOYSA-N
Canonical SMILES	CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2
Isomeric SMILES	CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2
PubChem CID	300471
Molecular Weight	400.52

Certificates

Certificate of Analysis(COA)

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Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
H1624055	Certificate of Analysis	Feb 20, 2024	E126032
L2017180	Certificate of Analysis	Oct 18, 2022	E126032
K2301079	Certificate of Analysis	May 09, 2022	E126032

Chemical and Physical Properties

Solubility	DMSO ≥78mg/mL Water <1.2mg/mL Ethanol <1.2mg/mL

FAQs and Articles

FAQ

Metabolic signaling pathway

Categories: Technical articles

Tags:

Carbohydrate metabolism Lipid metabolism Glutamic acid metabolism Nucleotide metabolism

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Elesclomol (STA-4783) - ≥98%, high purity , CAS No.488832-69-5

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Related Documents

FAQs and Articles

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
E126032-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$64.90
E126032-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$292.90
E126032-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$380.90