Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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E424149-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 |
Selective, casein kinase 2 (CK2) inhibitor
Synonyms | ellagic acid | 476-66-4 | Benzoaric acid | Elagostasine | Lagistase | Eleagic acid | Alizarine Yellow | 2,3,7,8-Tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione | Gallogen | Llagic acid | Acido elagico | Acidum ellagicum | Ellagicacid | Acide ellagique | Gallogen (astringent) | C.I. |
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Specifications & Purity | 2mM in DMSO |
Biochemical and Physiological Mechanisms | Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma. Contact activation in blood coagulation.Selective, ATP-competitive casein kinase 2 (CK2) inhibitor (K i = 20 nM). Exhibits a multitu |
Storage Temp | Protected from light,Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | A CK2, Topo I and II, FGR, GSK, and PKA inhibitor. |
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IUPAC Name | 6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione |
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INCHI | InChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H |
InChi Key | AFSDNFLWKVMVRB-UHFFFAOYSA-N |
Canonical SMILES | C1=C2C3=C(C(=C1O)O)OC(=O)C4=CC(=C(C(=C43)OC2=O)O)O |
Isomeric SMILES | C1=C2C3=C(C(=C1O)O)OC(=O)C4=CC(=C(C(=C43)OC2=O)O)O |
WGK Germany | 3 |
RTECS | DJ2620000 |
PubChem CID | 5281855 |
Molecular Weight | 302.19 |
Beilstein | 47549 |
Enter Lot Number to search for COA:
Sensitivity | Air sensitive.Light sensitive. |
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Melt Point(°C) | 360°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | DJ2620000 |
Merck Index | 3547 |
1. Shuaijun Lu, Hailong Tian, Bowen Li, Lei Li, Hao Jiang, Yajie Gao, Lin Zheng, Canhua Huang, Yuping Zhou, Zhongyan Du, Jia Xu. (2023) An Ellagic Acid Coordinated Copper-Based Nanoplatform for Efficiently Overcoming Cancer Chemoresistance by Cuproptosis and Synergistic Inhibition of Cancer Cell Stemness. Small, (2309215). [PMID:38044295] |
2. Edidiong Joseph Bassey, Jun-Hu Cheng, Da-Wen Sun. (2024) Comparative elucidation of bioactive and antioxidant properties of red dragon fruit peel as affected by electromagnetic and conventional drying approaches. FOOD CHEMISTRY, 439 (138118). [PMID:38109834] |
3. Sadia Munir, Wei Yue, Jinling Li, Xiaoyue Yu, Tianhao Ying, Ru Liu, Juan You, Shanbai Xiong, Yang Hu. (2023) Effects of Phenolics on the Physicochemical and Structural Properties of Collagen Hydrogel. Polymers, 15 (24): (4647). [PMID:38139899] |
4. Nan Li, Juan Zheng, Lu-Dan Yu, Yuan-Jun Tong, Xinying Gong, Yu Hou, Guosheng Chen, Jianqiao Xu, Fang Zhu, Gangfeng Ouyang. (2024) Green, mildly synthesized bismuth-based MOF for extraction of polar glucocorticoids in environmental water. JOURNAL OF HAZARDOUS MATERIALS, 461 (132477). [PMID:37716268] |
5. Yuanhang Xiao, Chunhua Wang, Jiajing Zhou, Jianhui Wu, Wei Lin. (2023) Modular design of vegetable polyphenols enables covalent bonding with collagen for eco-leather. INDUSTRIAL CROPS AND PRODUCTS, 204 (19): (117394). [PMID:20178741] |
6. Li Si, Zhou Donghui, Zhu Zuoxuan, Tan Xiaoyue, Tang Weiwei, Gong Junbo. (2023) Boosting inhibition performance of natural polyphenols for the prevention of calcium oxalate kidney stones through synergistic cooperativity. Communications Materials, 4 (1): (1-12). [PMID:23918938] |
7. Hao-Xiang Gao, Nan Chen, Qiang He, Bi Shi, Wei-Cai Zeng. (2024) Effects of structural characteristics of phenolic compounds on oxidation of glycerol trioleate: Action rule and mechanism. FOOD CHEMISTRY, 433 (137361). [PMID:37688816] |
8. Zhong-Xia Wang, Kai-Qi Liu, Xiang-Ying Meng, Feng Li, Heng-Ye Li, Hang Gao, Wei Wang. (2023) An eco-friendly fluorometric assay for high-sensitive meloxicam quantitation in biological matrices. ANALYST, 148 (18): (4339-4345). [PMID:37580992] |
9. Mao-Ling Luo, Hua Chen, Guo-Ying Chen, Shengpeng Wang, Yitao Wang, Feng-Qing Yang. (2023) Preparation of Alcohol Dehydrogenase–Zinc Phosphate Hybrid Nanoflowers through Biomimetic Mineralization and Its Application in the Inhibitor Screening. MOLECULES, 28 (14): (5429). [PMID:37513303] |
10. Jiezhou Pan, Haotian Liao, Guidong Gong, Yunxiang He, Qin Wang, Lang Qin, Yaoyao Zhang, Hirotaka Ejima, Blaise L. Tardy, Joseph J. Richardson, Jiaojiao Shang, Orlando J. Rojas, Yong Zeng, Junling Guo. (2023) Supramolecular nanoarchitectonics of phenolic-based nanofiller for controlled diffusion of versatile drugs in hydrogels. JOURNAL OF CONTROLLED RELEASE, 360 (433). [PMID:37422124] |
11. Jianmin Chen, Zemin He, Sijin Yu, Xiaozhen Cai, Danhong Zhu, Yanhua Lin. (2023) Xanthine oxidase inhibitory kinetics and mechanism of ellagic acid: In vitro, in silico and in vivo studies. IET Nanobiotechnology, 17 (4): (368-375). [PMID:37153957] |
12. Yichen Yin, Shiwei Sun, Hui Wang, Mengru Guo, Zhizhou Li, Chaoyi Lv, Zhao Yang, Wei Wang. (2023) Mechanism of interaction between urolithin A and α-glucosidase: Analysis by inhibition kinetics, fluorescence spectroscopy, isothermal titration calorimetry and molecular docking. JOURNAL OF MOLECULAR STRUCTURE, 1286 (135567). [PMID:] |
13. Minglu Zhang, Yi Zhang, Zhi-feng Cai. (2023) Selective determination of ellagic acid in aqueous solution using blue-green emissive copper nanoclusters. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 295 (122597). [PMID:36930836] |
14. Shengxiang Yi, Gaowei Zhang, Mingyan Liu, Wenjie Yu, Guohua Cheng, Liping Luo, Fangjian Ning. (2023) Citrus Honey Ameliorates Liver Disease and Restores Gut Microbiota in Alcohol–Feeding Mice. Nutrients, 15 (5): (1078). [PMID:36904078] |
15. Jiao Wu, Bingjun Han, Xiaoyu Chen, Jinglin Gao, Shan Zhao, Liping Sun, Shijie Wang. (2023) Quantification of bioactive components and evaluation of microbial community and antibacterial activity from Heterotrigona itama and Tetrigona binghami honeys. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 58 (5): (2247-2257). [PMID:] |
16. Linna Guo, Miao Tian, Lijuan Wang, Xin Zhou, Qianqian Wang, Lin Hao, Qiuhua Wu, Zhi Wang, Chun Wang. (2023) Synthesis of hydroxyl-functional magnetic hypercrosslinked polymer as high efficiency adsorbent for sensitively detecting neonicotinoid residues in water and lettuce samples. MICROCHEMICAL JOURNAL, 187 (108412). [PMID:] |
17. Ming Meng, Haofang Wan, Yida Bao, Yu He, Chang Li, Haitong Wan. (2023) Rapid identification, quantitation, and antioxidant activity evaluation of the components in Guanxin Shutong capsule with liquid chromatography and mass spectrometry. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 224 (115194). [PMID:36512869] |
18. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo. (2023) Chemical composition and anti-inflammatory activities of Castanopsis honey. Food & Function, 14 (1): (250-261). [PMID:36484340] |
19. Xuan Huang, Chunjun Yan, Ming Lin, Changwei He, Yanfei Xu, Yukun Huang, Zheng Zhou. (2022) The effects of conjugation of walnut protein isolate with polyphenols on protein solubility, antioxidant activity, and emulsifying properties. FOOD RESEARCH INTERNATIONAL, 161 (111910). [PMID:36193000] |
20. Nan Chen, Hao-Xiang Gao, Qiang He, Zhi-Long Yu, Wei-Cai Zeng. (2022) Influence of structure complexity of phenolic compounds on their binding with maize starch. Food Structure-Netherlands, 33 (100286). [PMID:] |
21. Ning Jin, Shouyu Zhang, Shibo Sun, Minghuo Wu, Xiaojing Yang, Jianqiang Xu, Kun Ma, Shui Guan, Weiping Xu. (2022) An Organic Solvent-Free Method for the Extraction of Ellagic Acid Compounds from Raspberry Wine Pomace with Assistance of Sodium Bicarbonate. MOLECULES, 27 (7): (2145). [PMID:35408544] |
22. Song Mengmeng, Xu Zhuicheng, Han Sixuan, Sheng Xianjie, Chen Yan, Li Xinru, Su Yan, Li Qin, Shan Chenxiao, Xie Tong, Kang An. (2022) Systematic Identification of the Main Constituents from Agrimonia pilosa Ledeb. and Their Metabolites in Rats using HPLC-Q-TOF-MS/MS. PLANTA MEDICA, 88 (14): (1369-1383). [PMID:35062039] |
23. Zhang Yameng, Shen Xinming, Hu Lei, Wu Zhen, Wang Xiaoyu, Jiang Yetao. (2022) Zirconium-lignin hybrid catalyst for the Meerwein-Ponndorf-Verley reduction of biomass-derived 5-hydroxymethylfurfural to 2,5-bis(hydroxymethyl)furan. Biomass Conversion and Biorefinery, (1-17). [PMID:] |
1. Shuaijun Lu, Hailong Tian, Bowen Li, Lei Li, Hao Jiang, Yajie Gao, Lin Zheng, Canhua Huang, Yuping Zhou, Zhongyan Du, Jia Xu. (2023) An Ellagic Acid Coordinated Copper-Based Nanoplatform for Efficiently Overcoming Cancer Chemoresistance by Cuproptosis and Synergistic Inhibition of Cancer Cell Stemness. Small, (2309215). [PMID:38044295] |
2. Edidiong Joseph Bassey, Jun-Hu Cheng, Da-Wen Sun. (2024) Comparative elucidation of bioactive and antioxidant properties of red dragon fruit peel as affected by electromagnetic and conventional drying approaches. FOOD CHEMISTRY, 439 (138118). [PMID:38109834] |
3. Sadia Munir, Wei Yue, Jinling Li, Xiaoyue Yu, Tianhao Ying, Ru Liu, Juan You, Shanbai Xiong, Yang Hu. (2023) Effects of Phenolics on the Physicochemical and Structural Properties of Collagen Hydrogel. Polymers, 15 (24): (4647). [PMID:38139899] |
4. Nan Li, Juan Zheng, Lu-Dan Yu, Yuan-Jun Tong, Xinying Gong, Yu Hou, Guosheng Chen, Jianqiao Xu, Fang Zhu, Gangfeng Ouyang. (2024) Green, mildly synthesized bismuth-based MOF for extraction of polar glucocorticoids in environmental water. JOURNAL OF HAZARDOUS MATERIALS, 461 (132477). [PMID:37716268] |
5. Yuanhang Xiao, Chunhua Wang, Jiajing Zhou, Jianhui Wu, Wei Lin. (2023) Modular design of vegetable polyphenols enables covalent bonding with collagen for eco-leather. INDUSTRIAL CROPS AND PRODUCTS, 204 (19): (117394). [PMID:20178741] |
6. Li Si, Zhou Donghui, Zhu Zuoxuan, Tan Xiaoyue, Tang Weiwei, Gong Junbo. (2023) Boosting inhibition performance of natural polyphenols for the prevention of calcium oxalate kidney stones through synergistic cooperativity. Communications Materials, 4 (1): (1-12). [PMID:23918938] |
7. Hao-Xiang Gao, Nan Chen, Qiang He, Bi Shi, Wei-Cai Zeng. (2024) Effects of structural characteristics of phenolic compounds on oxidation of glycerol trioleate: Action rule and mechanism. FOOD CHEMISTRY, 433 (137361). [PMID:37688816] |
8. Zhong-Xia Wang, Kai-Qi Liu, Xiang-Ying Meng, Feng Li, Heng-Ye Li, Hang Gao, Wei Wang. (2023) An eco-friendly fluorometric assay for high-sensitive meloxicam quantitation in biological matrices. ANALYST, 148 (18): (4339-4345). [PMID:37580992] |
9. Mao-Ling Luo, Hua Chen, Guo-Ying Chen, Shengpeng Wang, Yitao Wang, Feng-Qing Yang. (2023) Preparation of Alcohol Dehydrogenase–Zinc Phosphate Hybrid Nanoflowers through Biomimetic Mineralization and Its Application in the Inhibitor Screening. MOLECULES, 28 (14): (5429). [PMID:37513303] |
10. Jiezhou Pan, Haotian Liao, Guidong Gong, Yunxiang He, Qin Wang, Lang Qin, Yaoyao Zhang, Hirotaka Ejima, Blaise L. Tardy, Joseph J. Richardson, Jiaojiao Shang, Orlando J. Rojas, Yong Zeng, Junling Guo. (2023) Supramolecular nanoarchitectonics of phenolic-based nanofiller for controlled diffusion of versatile drugs in hydrogels. JOURNAL OF CONTROLLED RELEASE, 360 (433). [PMID:37422124] |
11. Jianmin Chen, Zemin He, Sijin Yu, Xiaozhen Cai, Danhong Zhu, Yanhua Lin. (2023) Xanthine oxidase inhibitory kinetics and mechanism of ellagic acid: In vitro, in silico and in vivo studies. IET Nanobiotechnology, 17 (4): (368-375). [PMID:37153957] |
12. Yichen Yin, Shiwei Sun, Hui Wang, Mengru Guo, Zhizhou Li, Chaoyi Lv, Zhao Yang, Wei Wang. (2023) Mechanism of interaction between urolithin A and α-glucosidase: Analysis by inhibition kinetics, fluorescence spectroscopy, isothermal titration calorimetry and molecular docking. JOURNAL OF MOLECULAR STRUCTURE, 1286 (135567). [PMID:] |
13. Minglu Zhang, Yi Zhang, Zhi-feng Cai. (2023) Selective determination of ellagic acid in aqueous solution using blue-green emissive copper nanoclusters. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 295 (122597). [PMID:36930836] |
14. Shengxiang Yi, Gaowei Zhang, Mingyan Liu, Wenjie Yu, Guohua Cheng, Liping Luo, Fangjian Ning. (2023) Citrus Honey Ameliorates Liver Disease and Restores Gut Microbiota in Alcohol–Feeding Mice. Nutrients, 15 (5): (1078). [PMID:36904078] |
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