EML 425 - ≥98%(HPLC), high purity , CAS No.1675821-32-5

Item Number

E288079

Grouped product items
SKU	Size	Availability	Price
E288079-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$187.90
E288079-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$846.90
E288079-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$3,807.90

Reversible and non-competitive CBP/p300 inhibitor

Basic Description

Synonyms	5-[(4-Hydroxy-2,6-dimethylphenyl)methylene]-1,3-bis(phenylmethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Reversible and non-competitive CBP/p300 inhibitor (IC50values are 1.1 and 2.9μM, respectively). Cell permeable.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

EP300 Tchem Histone acetyltransferase p300 (1259 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KAT2B Tchem Histone acetyltransferase PCAF (884 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CREBBP Tchem CREB-binding protein (1602 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	1,3-dibenzyl-5-[(4-hydroxy-2,6-dimethylphenyl)methylidene]-1,3-diazinane-2,4,6-trione
INCHI	InChI=1S/C27H24N2O4/c1-18-13-22(30)14-19(2)23(18)15-24-25(31)28(16-20-9-5-3-6-10-20)27(33)29(26(24)32)17-21-11-7-4-8-12-21/h3-15,30H,16-17H2,1-2H3
InChi Key	LUGQBJDYUPNAQQ-UHFFFAOYSA-N
Canonical SMILES	CC1=CC(=CC(=C1C=C2C(=O)N(C(=O)N(C2=O)CC3=CC=CC=C3)CC4=CC=CC=C4)C)O
Isomeric SMILES	CC1=CC(=CC(=C1C=C2C(=O)N(C(=O)N(C2=O)CC3=CC=CC=C3)CC4=CC=CC=C4)C)O
PubChem CID	91826273
Molecular Weight	440.49

Certificates

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3 results found

Lot Number	Certificate Type	Date	Item
J2130517	Certificate of Analysis	Aug 14, 2024	E288079
J2130524	Certificate of Analysis	Aug 14, 2024	E288079
J2130577	Certificate of Analysis	Aug 14, 2024	E288079

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Basic Description