Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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E129304-1g | 1g | In stock | $48.90 | |
E129304-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $167.90 | |
E129304-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $756.90 | |
E129304-100g | 100g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,721.90 |
Angiotensin converting enzyme inhibitor
Synonyms | Enalapril maleate | 76095-16-4 | Renitec | Glioten | Vasotec | Enalapril maleate salt | Enapren | Innovace | Naprilene | Renivace | Xanef | Baripril | Benalapril | Crinoren | Hipoartel | Amprace | Dabonal | Enacard | Reniten | Pres | Enalapril (maleate) | MK-421 | Renitek | Epaned | MK-421 Maleate | enal |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Enalapril Maleate is an effective and potent nonsulfhydryl ACE(angiotenson-converting enzyme) inhibitor. The compound has been used to study diabetic angiopathy in diabetic rats and inhibition of ACE in hog plasma (I50=1.2nM). ACE inhibitors disturb the e |
Shipped In | Normal |
Action Type | INHIBITOR |
Mechanism of action | Angiotensin-converting enzyme inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Enalapril Maleate, the active metabolite of enalapril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. |
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IUPAC Name | (Z)-but-2-enedioic acid;(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid |
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INCHI | InChI=1S/C20H28N2O5.C4H4O4/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25;5-3(6)1-2-4(7)8/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,16-,17-;/m0./s1 |
InChi Key | OYFJQPXVCSSHAI-QFPUQLAESA-N |
Canonical SMILES | CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O.C(=CC(=O)O)C(=O)O |
Isomeric SMILES | CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)O.C(=C\C(=O)O)\C(=O)O |
WGK Germany | 2 |
RTECS | TW3666000 |
Alternate CAS | 75847-73-3 |
PubChem CID | 5388961 |
Molecular Weight | 492.52 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
C2211164 | Certificate of Analysis | Dec 12, 2023 | E129304 |
C2211242 | Certificate of Analysis | Dec 12, 2023 | E129304 |
C2211245 | Certificate of Analysis | Dec 12, 2023 | E129304 |
F1526059 | Certificate of Analysis | Jan 19, 2023 | E129304 |
A2119162 | Certificate of Analysis | Nov 16, 2022 | E129304 |
A2119161 | Certificate of Analysis | Nov 15, 2022 | E129304 |
C2211323 | Certificate of Analysis | Jan 21, 2022 | E129304 |
G2308097 | Certificate of Analysis | Jan 21, 2022 | E129304 |
Solubility | Soluble in water (25 mg/ml), methanol (50 mg/ml), and ethanol (8 mg/ml). |
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Specific Rotation[α] | [α]D: -41° (C=1,MeOH) |
Melt Point(°C) | 143-145° |
Pictogram(s) | GHS08, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H319:Causes serious eye irritation H302:Harmful if swallowed H318:Causes serious eye damage H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child H361:Suspected of damaging fertility or the unborn child H362:May cause harm to breast-fed children |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 2 |
RTECS | TW3666000 |
Merck Index | 3567 |