Enapotamab (anti-AXL) - Primary antibody, specific to AXL, >95%, high purity, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
Features and benefits
  • Host species: Human
  • Species reactivity(Reacts with): Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
Item Number
Ab177845
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab177845-100μg
100μg
In stock
$69.90
Ab177845-1mg
1mg
In stock
$309.90
Ab177845-5mg
5mg
In stock
$789.90
Ab177845-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,259.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product NameEnapotamab (anti-AXL) - Primary antibody, specific to AXL, >95%, high purity, Human IgG1
SynonymsAXL oncogene | EC 2.7.10.1
Specifications & PurityExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC), Lot by Lot
Host speciesHuman
SpecificityAXL
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Enapotamab (anti-AXL) is an anti-AXL/UFO reference antibody. Enapotamab (anti-AXL) can be used to synthesis Bcl-xl inhibitor antibody-drug conjugates.

Product Properties

IsotypeHuman IgG1
Light Chain Typekappa
SDS-PAGE26.4 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 195.7 kDa, under non-reducing conditions.
Purification MethodProtein A purified
Purity>95%
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -80°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS1912423-61-0

Images

Enapotamab (anti-AXL) (Ab177845) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling AXL (red) with Enapotamab (anti-AXL) (Ab177845). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Enapotamab (anti-AXL) (Ab177845) - ELISA
Immobilized hu-Axl-ECD-FC(IgG1) at 2 μg/mL can bind Enapotamab (anti-AXL) (Ab177845) with the EC₅₀ of 13.86 ng/mL

Enapotamab (anti-AXL) (Ab177845) - SEC
The purity of Enapotamab (anti-AXL) (Ab177845) is more than 95% verified by HPLC.

Associated Targets(Human)

AXL Tchem Tyrosine-protein kinase receptor UFO (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AXL Tchem Tyrosine-protein kinase receptor UFO (3469 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AXL Tchem TEL/AXL (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303120Certificate of AnalysisMar 12, 2024 Ab177845
ZJ24F0303119Certificate of AnalysisMar 12, 2024 Ab177845
ZJ24F0303118Certificate of AnalysisMar 12, 2024 Ab177845

Related Documents

References

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78. Mori, Masamichi M and 8 more authors..  (2017)  Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia..  Investigational new drugs,      [PMID:28516360]
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80. Strange, Daniel P DP and 7 more authors..  (2019)  Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells..  mBio,    (16):   [PMID:31311882]
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