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EOAI3402143 - 98%, high purity , CAS No.1699750-95-2

≥98%

CAS#: 1699750-95-2
Formula: C₂₅H₂₈Cl₂N₄O₃
Molecular Weight: 503.42
PubChem CID: 91669215

Item Number

E413664

Grouped product items
SKU	Size	Availability	Price
E413664-5mg	5mg	In stock	$177.90
E413664-10mg	10mg	In stock	$286.90
E413664-25mg	25mg	In stock	$563.90
E413664-50mg	50mg	In stock	$901.90
E413664-100mg	100mg	In stock	$1,444.90

USP/UBP Selective Inhibitors

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	EOAI3402143 is a dose-dependent inhibitor of Usp9x, Usp24 and Usp5 that increases tumor cell apoptosis, and fully blocks or regresses myeloma tumors in mice.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Information EOAI3402143 is a dose-dependent inhibitor ofUsp9x,Usp24andUsp5that increases tumor cellapoptosis, and fully blocks or regresses myeloma tumors in mice. Targets Usp9x ; Usp24 ; USP5

ALogP

4.911

HBD Count

Rotatable Bond

Associated Targets(Human)

STAT3 Tchem Signal transducer and activator of transcription 3 (3313 Activities)

Discover Target: STAT3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A-375 (9258 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

USP5 Tchem Ubiquitin carboxyl-terminal hydrolase 5 (172 Activities)

Discover Target: USP5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

USP9X Tbio Probable ubiquitin carboxyl-terminal hydrolase FAF-X (500 Activities)

Discover Target: USP9X

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A375/R (12 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CD34-positive blood stem/progenitor cell (1 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NCI-H929 (451 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MM1.S (1111 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

USP24 Tbio Ubiquitin carboxyl-terminal hydrolase 24 (1 Activities)

Discover Target: USP24

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Sindbis virus (1599 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

La Crosse virus (130 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Murine norovirus (30 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Tulane virus (2 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Norwalk virus (1 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(E)-2-cyano-3-(3,6-dichloropyridin-2-yl)-N-[1-[4-(2-morpholin-4-ylethoxy)phenyl]butyl]prop-2-enamide
INCHI	InChI=1S/C25H28Cl2N4O3/c1-2-3-22(30-25(32)19(17-28)16-23-21(26)8-9-24(27)29-23)18-4-6-20(7-5-18)34-15-12-31-10-13-33-14-11-31/h4-9,16,22H,2-3,10-15H2,1H3,(H,30,32)/b19-16+
InChi Key	IIKVQQNZHGBYGQ-KNTRCKAVSA-N
Canonical SMILES	CCCC(C1=CC=C(C=C1)OCCN2CCOCC2)NC(=O)C(=CC3=C(C=CC(=N3)Cl)Cl)C#N
Isomeric SMILES	CCCC(C1=CC=C(C=C1)OCCN2CCOCC2)NC(=O)/C(=C/C3=C(C=CC(=N3)Cl)Cl)/C#N
PubChem CID	91669215
Molecular Weight	503.42

Certificates

Certificate of Analysis(COA)

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10 results found

Lot Number	Certificate Type	Date	Item
H2303732	Certificate of Analysis	Jul 19, 2023	E413664
H2303741	Certificate of Analysis	Jul 19, 2023	E413664
H2303747	Certificate of Analysis	Jul 19, 2023	E413664
H2303758	Certificate of Analysis	Jul 19, 2023	E413664
H2303766	Certificate of Analysis	Jul 19, 2023	E413664
H2303771	Certificate of Analysis	Jul 19, 2023	E413664
H2303775	Certificate of Analysis	Jul 19, 2023	E413664
H2303786	Certificate of Analysis	Jul 19, 2023	E413664
H2303804	Certificate of Analysis	Jul 19, 2023	E413664
H2303864	Certificate of Analysis	Jul 19, 2023	E413664

Solubility

Solubility (25°C) In vitro DMSO: 100 mg/mL (198.64 mM); Water: Insoluble; Ethanol: Insoluble;

DMSO(mg / mL) Max Solubility

100

DMSO(mM) Max Solubility

198.641293552104

Water(mg / mL) Max Solubility

＜1

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