Epetraborole hydrochloride - 99%, high purity , CAS No.1234563-16-6

Item Number

E649466

Grouped product items
SKU	Size	Availability	Price
E649466-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$70.90
E649466-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$140.90
E649466-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$230.90
E649466-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$510.90
E649466-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$820.90
E649466-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,320.90

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Basic Description

Synonyms	Epetraborole hydrochloride\|1234563-16-6\|Epetraborole HCl\|Epetraborole (hydrochloride)\|AN3365(Epetraborole)\|MM0NZY12FA\|GSK2251052 hydrochloride\|(S)-3-(aminomethyl)-7-(3-hydroxypropoxy)benzo[c][1,2]oxaborol-1(3H)-ol hydrochloride\|1-Propanol, 3-[[(3S)-3-(ami
Specifications & Purity	99%
Storage Temp	Store at 2-8°C,Desiccated
Shipped In	Wet ice
Product Description	Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase ( LeuRS ) inhibitor ( IC 50 =0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research In Vitro Epetraborole (0-32 μg/mL) shows anti-bacterial activity against key gram-negative aerobic and anaerobic pathogens and gram-positive anaerobes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: Anaerobes isolates Concentration: 0-32 μg/mL Incubation Time: Result: Showed MIC 50 /MIC 90 for all anaerobes isolates tested of 2 and 4 μg/mL, respectively. Form:Solid IC50& Target:IC 50 : 0.31 μM (LeuRS)

Names and Identifiers

IUPAC Name	3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol;hydrochloride
INCHI	InChI=1S/C11H16BNO4.ClH/c13-7-10-8-3-1-4-9(16-6-2-5-14)11(8)12(15)17-10;/h1,3-4,10,14-15H,2,5-7,13H2;1H/t10-;/m1./s1
InChi Key	DADYQGIQOBJGIW-HNCPQSOCSA-N
Canonical SMILES	B1(C2=C(C=CC=C2OCCCO)C(O1)CN)O.Cl
Isomeric SMILES	B1(C2=C(C=CC=C2OCCCO)[C@H](O1)CN)O.Cl
Alternate CAS	1234563-16-6
PubChem CID	52918389
Molecular Weight	273.52

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Basic Description