EphA2 Mouse mAb - Primary antibody, specific to Eph receptor A2, Mouse IgG1

    Application:
  • Flow Cytometry
Features and benefits
  • Host species: Mouse
  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG1
  • Clone Number: SHM16
  • Conjugation: Unconjugated
Item Number
Ab101885
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab101885-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab101885-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
Ab101885-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$249.90
Ab101885-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90

mAb (SHM16); Mouse anti Human EphA2 Antibody; Flow; Unconjugated

Basic Description

Product NameEphA2 Mouse mAb - Primary antibody, specific to Eph receptor A2, Mouse IgG1
SynonymsECK | CTPA | CTPP1 | CTRCT6 | ARCC2 | EC 2.7.10 | EC 2.7.10.1 | Eck | ECKepithelial cell receptor protein tyrosine kinase | EPH receptor A2 | EphA2 | ephrin type-A receptor 2 | Epithelial cell kinase | Myk2 | Sek2 | soluble EPHA2 variant 1 | Tyrosine-prot
Specifications & PurityValidated, Carrier Free, Azide Free, ≥95%(SDS-PAGE), Lot by Lot
Host speciesMouse
SpecificityEph receptor A2
ImmunogenRecombinant mouse EphA2 extracellular domain
ConjugationUnconjugated
GradeAzide Free, Carrier Free, Validated
Product Description

Mouse anti Human EphA2 Antibody, Monoclonal (SHM16), could be used for Flow and so on.
Application:
Flow: Use at an assay dependent concentration.
Protein Function
Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). Induces apoptosis in a p53/TP53-independent, caspase-8-dependent manner.

Product Properties

IsotypeMouse IgG1
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein G purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at 2-8°C,Freeze prohibited
Shipped InWet ice
Stability And StorageShipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon delivery aliquot.

Images

EphA2 Mouse mAb (Ab101885) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling EphA2 (red) with EphA2 Mouse mAb (Ab101885) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

EphA2 Mouse mAb (Ab101885) - Flow Cytometry
Flow Cytometry analysis of A375 cells labelling EphA2 (red) with EphA2 Mouse mAb (Ab101885) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Associated Targets(Human)

EPHA2 Tclin Ephrin type-A receptor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EPHA2 Tclin Ephrin type-A receptor 2 (3499 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EPHA2 Tclin Ephrin receptor (0 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EPHA2 Tclin Ephrin type-A receptor 2/Ephrin-A1 (2 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
Flow Cytometry

Use at an assay dependent concentration.

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators