Epicatechin enhances the skeletal muscle structure in heart failure patients and minimizes cardiometabolic risks. It can be used for treating sarcopenia. Epicatechin reduces myostatin and β-galactosidase and increases the level of markers of muscle growth
Source
Tea
Storage Temp
Store at 2-8°C,Argon charged
Shipped In
Wet ice
Grade
Moligand™
Product Description
Epicatechin is a flavanol. Cacao products are rich in epicatechin. Epicatechin enhances the skeletal muscle structure in heart failure patients and minimises the cardiometabolic risks. It can be used for treating sarcopenia. Epicatechin reduces myostatin and β-galactosidase and increases the level of markers of muscle growth. Antioxidant found in chocolate.
Product description：
(-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
Application：
(−)-Epicatechin (EC) has been used:
as an antioxidant to downregulate nicotinamide adenine dinucleotide phosphate hydrogen (NADPH) oxidase and improve insulin sensitivity in in vivo (high fat-fed mice) and in vitro (HepG2 cells) studies
to study its effect on blood pressure, nitric oxide synthase (NOS) activity and anxiety-like behavior on borderline hypertensive rat (BHR) models
to test its effect on neuronal survival in the hippocampus of middle-aged rats on swimming training, under oxidative stress
to study its antioxidant activity in dark chocolate
as a characteristic compound in polyphenols analysis
C2430071