(-)-Epicatechin gallate - analytical standard,≥98%, high purity , CAS No.1257-08-5, Agonist of TAS2R39

Item Number
E101658
Grouped product items
SKUSizeAvailabilityPrice Qty
E101658-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$127.90
E101658-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$443.90

Apoptosis inducer

View related series
Flavonoids [Phytochemicals]

Basic Description

SynonymsAKOS015965216 | DTXSID70925231 | trans-4-[N-ethyl-N-(2-hydroxyethyl)amino]-4'-nitroazobenzene | KBio2_003362 | S)-1-Amino-1,2,3,4-tetrahydronaphthalene | KBio3_001132 | (-)-Epicatechin 3-O-gallate | NCGC00179135-01 | 2-(Dimethylamino)ethyl Methacrylate, (
Specifications & PurityMoligand™, analytical standard, ≥98%
Biochemical and Physiological Mechanisms(-)Epicatechin gallate is a polyphenol apoptosis inducer in tumor cells commonly found in green tea. Studies suggest that (-)Epicatechin gallate causes anti-proliferative and anti-inflammatory effects on pancreatic ductal adenocarcinoma cells. Alternate s
Storage TempStore at 2-8°C
Shipped InWet ice
Gradeanalytical standard, Moligand™
Action TypeAGONIST
Mechanism of actionAgonist of TAS2R39
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

An antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria.

Associated Targets(Human)

ELAVL3 Tchem ELAV-like protein 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RAD52 Tchem DNA repair protein RAD52 homolog (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PSMB5 Tclin Proteasome subunit beta type-5 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TAS2R39 Tchem Taste receptor type 2 member 39 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
BCL2 Tclin Apoptosis regulator Bcl-2 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PGD Tchem 6-phosphogluconate dehydrogenase, decarboxylating (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DHFR Tclin Dihydrofolate reductase (3072 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR2 Tchem Cannabinoid CB2 receptor (16942 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAPK14 Tchem MAP kinase p38 alpha (12866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALB Tchem Serum albumin (2651 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DAPK1 Tchem Death-associated protein kinase 1 (1664 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MET Tclin Hepatocyte growth factor receptor (10718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FASN Tchem Fatty acid synthase (3390 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGD Tchem 6-phosphogluconate dehydrogenase (58 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DYRK1A Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 1A (6484 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADAMTS4 Tchem ADAMTS4 (425 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADAMTS5 Tchem ADAMTS5 (711 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Caco-2 (12174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-8 (3484 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-OV-3 (52876 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TE-671 (161 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U373 MG (658 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
T47D (39041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
H9 (1832 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KB (17409 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCL2 Tclin Apoptosis regulator Bcl-2 (3787 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PSMB5 Tclin Proteasome Macropain subunit MB1 (2451 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
G6PD Tchem Glucose-6-phosphate 1-dehydrogenase (778 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (1191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ARNT Tbio Aryl hydrocarbon receptor nuclear translocator (25 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNCA Tchem Alpha-synuclein (10960 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 (580 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SIRT6 Tchem NAD-dependent protein deacetylase sirtuin-6 (671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HIF1A Tchem Hypoxia inducible factors; HIF-1-alpha, HIF-2-alpha (820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAD52 Tchem DNA repair protein RAD52 homolog (856 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ELAVL3 Tchem ELAV-like protein 3 (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMC1 (49 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SYNJ2 Tchem Synaptojanin-2 (76 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SYNJ1 Tchem Synaptojanin-1 (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

fabI Enoyl-[acyl-carrier-protein] reductase (206 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pol Human immunodeficiency virus type 1 protease (9113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pol Human immunodeficiency virus type 1 reverse transcriptase (18245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp13 Matrix metalloproteinase 13 (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcc1 Multidrug resistance-associated protein 1 (42 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Micrococcus luteus (7463 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus epidermidis (22802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Proteus mirabilis (3894 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecalis (29875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pichia kudriavzevii (7448 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida tropicalis (8381 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human alphaherpesvirus 2 (4932 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Influenza B virus (2113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Clavispora lusitaniae (671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
H9c2 (3506 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDCK (10148 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NIH3T3 (5395 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fabG 3-oxoacyl-acyl-carrier protein reductase (70 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fabI Enoyl-acyl-carrier protein reductase (415 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Genome polyprotein (620 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lasiodiplodia theobromae (193 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasma (328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Diplodia seriata (145 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Diplodia mutila (102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Neofusicoccum luteum (172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Botryosphaeria dothidea (71 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Neofusicoccum parvum (61 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phaeoacremonium minimum (24 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
groL GroEL/GroES (1042 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name [(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
INCHI InChI=1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21-/m1/s1
InChi Key LSHVYAFMTMFKBA-TZIWHRDSSA-N
Canonical SMILES C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Isomeric SMILES C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
WGK Germany 3
RTECS DH9030000
Alternate CAS 1257-08-5
PubChem CID 107905
MeSH Entry Terms epicatechin gallate;epicatechin gallate, (2R-cis)-isomer;epicatechin-3-gallate;epicatechin-3-galloyl ester;epicatechin-3-O-gallate
Molecular Weight 442.37

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
J2415359Certificate of AnalysisSep 23, 2024 E101658
J2415360Certificate of AnalysisSep 23, 2024 E101658
J2415370Certificate of AnalysisSep 23, 2024 E101658
I2306428Certificate of AnalysisAug 24, 2023 E101658
I2306429Certificate of AnalysisAug 24, 2023 E101658
K2113576Certificate of AnalysisAug 04, 2023 E101658
B2314291Certificate of AnalysisDec 30, 2022 E101658
B2314304Certificate of AnalysisDec 30, 2022 E101658
A1921031Certificate of AnalysisSep 12, 2022 E101658

Chemical and Physical Properties

SolubilitySoluble in water (5 mg/ml) with heat and sonication as needed, yielding a clear, colorless solution, ethanol (~1 mg/ml), methanol (sparingly), DMSO (~10 mg/ml), and DMF (~14 mg/ml).
SensitivityHeat sensitive
Specific Rotation[α]-177° (C=1,EtOH)
Melt Point(°C)255°C(lit.)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS DH9030000

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1. Jun Li, Fangbo Yuan, Jiayou Teng, Fang Li, Penghui Zhou, Yanlan Bi.  (2023)  Effects of tea polyphenols and tertiary butylhydroquinone on quality of palm oils and losses of endogenous vitamin E during batch frying and oxidative stability of fried instant noodles.  Food Chemistry-X,  20  (101049).  [PMID:38144856]
2. Yuqing Zhong, Yongling Lu, Lishuang Lv.  (2023)  Theanine in Tea: An Effective Scavenger of Single or Multiple Reactive Carbonyl Species at the Same Time.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  71  (45): (17153–17162).  [PMID:37906124]
3. Yating Guo, Yili Shen, Boya Hu, Huichun Ye, Haowei Guo, Qiang Chu, Ping Chen.  (2023)  Decoding the Chemical Signatures and Sensory Profiles of Enshi Yulu: Insights from Diverse Tea Cultivars.  Plants-Basel,  12  (21): (3707).  [PMID:37960063]
4. Yingyi Huang, Huahong Liu, Xiaohua Zhang, Yuxin Wu, Zhusheng Liu, Yuelan Pang, Renjun Liu, Chun Yang, Jinfang Nie.  (2023)  Impact of storage time on non-volatile metabolites and fungal communities in Liupao tea using LC-MS based non-targeted metabolomics and high-throughput sequencing.  FOOD RESEARCH INTERNATIONAL,  174  (3): (113615).  [PMID:37986470]
5. Cheng Guo, Wangyang Shen, Weiping Jin, Xiwu Jia, Zhili Ji, Jinling Li, Bin Li.  (2023)  Dynamic Formation of Green Tea Cream and the Identification of Key Components Using the “Knock-Out/Knock-In” Method.  Foods,  12  (16): (2987).  [PMID:37627986]
6. Xiaojuan Chen, Bojia Li, Sicheng Ji, Di Wu, Bing Cui, Xingling Ren, Bin Zhou, Bin Li, Hongshan Liang.  (2023)  Small molecules interfacial assembly regulate the crystallization transition process for nobiletin stabilization.  FOOD CHEMISTRY,  426  (136519).  [PMID:37329798]
7. Su Zhou, Jiaying Yang, Yani Pan, Xinyu Feng, Hao Hu, Shicheng Ma, Cansong Ou, Fangyuan Fan, Shuying Gong, Yuefei Wang, Ping Chen, Qiang Chu.  (2023)  Pu’ er raw tea extract alleviates DSS-induced colitis in mice by restoring intestinal barrier function and maintaining gut microbiota homeostasis.  Food Bioscience,  53  (102750).  [PMID:]
8. Shengkai Luo, Yi Hou, Song-Qing Hu.  (2023)  Proteolytic activation and characterization of recombinant polyphenol oxidase from Rosa chinensis for efficient synthesis of theaflavins.  INDUSTRIAL CROPS AND PRODUCTS,  200  (116810).  [PMID:]
9. Lixia Yang, Zhendong Lu, Jian Lu, Dianhui Wu.  (2022)  Evaluation of the antioxidant characteristics of craft beer with green tea.  JOURNAL OF FOOD SCIENCE,  88  (2): (625-637).  [PMID:36576119]
10. Xiao-Hua Zhang, Hui-Na Cui, Jing-Jing Zheng, Xiang-Dong Qing, Kai-Long Yang, Ya-Qian Zhang, Lu-Meng Ren, Le-Yuan Pan, Xiao-Li Yin.  (2023)  Discrimination of the harvesting season of green tea by alcohol/salt-based aqueous two-phase systems combined with chemometric analysis.  FOOD RESEARCH INTERNATIONAL,  163  (112278).  [PMID:36596188]
11. He Wen-Jing, Chen Nan, Yu Zhi-Long, Sun Qun, He Qiang, Zeng Wei-Cai.  (2022)  Effect of Structure Complexity of Catechins on the Properties of Glutenin: the Rule, Action Mechanism and Application.  Food Biophysics,  17  (4): (586-597).  [PMID:]
12. Wen-Jing He, Nan Chen, Zhi-Long Yu, Qun Sun, Qiang He, Wei-Cai Zeng.  (2022)  Gliadin interacted with tea polyphenols: potential application and action mechanism.  INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION,  73  (6): (786-799).  [PMID:35603582]
13. Yao Liu, Ruifang Sun, XiaoPing Lin, Lanlan Wu, Hengying Chen, Siwen Shen, Yan Li, Yuanhuan Wei, Guifang Deng.  (2022)  Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-κB and NLRP3 inflammasome pathway.  BIOMEDICINE & PHARMACOTHERAPY,  151  (113078).  [PMID:35567986]
14. Linjun Li, Jinsuo Lu, Heliang Pang, Zhiqiang Zhang, Jing Yang, Pengpeng Li, Xiaoyu Yan, Miaomiao Fan.  (2023)  New insight into scale inhibition during tea brewing: Ca2+/Mg2+ complexing and alkalinity consumption.  Journal of Environmental Sciences,  124  (901).  [PMID:36182193]
15. Hui-Wen Gu, Xiao-Li Yin, Tian-Qin Peng, Yuan Pan, Hui-Na Cui, Zhi-Quan Li, Weiqing Sun, Baomiao Ding, Xian-Chun Hu, Zi-Hong Zhang, Zhi Liu.  (2022)  Geographical origin identification and chemical markers screening of Chinese green tea using two-dimensional fingerprints technique coupled with multivariate chemometric methods.  FOOD CONTROL,  135  (108795).  [PMID:]
16. Qian Li, Mengran Duan, Lu Liu, Xiaoqiang Chen, Yinxin Fu, Jing Li, Tiantian Zhao, David Julian McClements.  (2021)  Impact of Polyphenol Interactions with Titanium Dioxide Nanoparticles on Their Bioavailability and Antioxidant Activity.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  69  (33): (9661–9670).  [PMID:34376052]
17. Ming-Xi Zhou, Xing Tian, Zhong-Qin Wu, Ke Li, Zong-Jun Li.  (2021)  Fuzhuan brick tea supplemented with areca nuts: Effects on serum and gut microbiota in mice.  JOURNAL OF FOOD BIOCHEMISTRY,  45  (5): (e13737).  [PMID:33876445]
18. Yu-Meng Zhu, Jun-Jie Dong, Jing Jin, Jin-Hua Liu, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye.  (2021)  Roasting process shaping the chemical profile of roasted green tea and the association with aroma features.  FOOD CHEMISTRY,  353  (129428).  [PMID:33714119]
19. Tian-Qin Peng, Xiao-Li Yin, Hui-Wen Gu, Weiqing Sun, Baomiao Ding, Xian-Chun Hu, Li-An Ma, Shu-Dong Wei, Zhi Liu, Shi-Yi Ye.  (2021)  HPLC-DAD fingerprints combined with chemometric techniques for the authentication of plucking seasons of Laoshan green tea.  FOOD CHEMISTRY,  347  (128959).  [PMID:33465688]
20. Fei Zhou, Weisu Huang, Tao Xu, Lipeng Wu, Qi Chen, Jiyu Peng, Xin Liu, Baiyi Lu.  (2020)  Natural P-gp inhibitor EGCG improves the acteoside absorption in Caco-2 cell monolayers and increases the oral bioavailability of acteoside in rats.  FOOD AND CHEMICAL TOXICOLOGY,  146  (111827).  [PMID:33184029]
21. Dandan Qin, Qiushuang Wang, Hongjian Li, Xiaohui Jiang, Kaixing Fang, Qing Wang, Bo Li, Chendong Pan, Hualing Wu.  (2020)  Identification of key metabolites based on non-targeted metabolomics and chemometrics analyses provides insights into bitterness in Kucha [Camellia kucha (Chang et Wang) Chang].  FOOD RESEARCH INTERNATIONAL,  138  (109789).  [PMID:33288175]
22. Xiao-Hua Zhang, Qian Zhou, Zhi Liu, Xiang-Dong Qing, Jing-Jing Zheng, Shu-Ting Mu, Pan-Hua Liu.  (2020)  Comparison of three second-order multivariate calibration methods for the rapid identification and quantitative analysis of tea polyphenols in Chinese teas using high-performance liquid chromatography.  JOURNAL OF CHROMATOGRAPHY A,  1618  (460905).  [PMID:32008825]
23. Huanhuan Xu, Titi Liu, Jing Xu, Jin Li, Fei Chen, Zemin Xiang, Yewei Huang, Dongying Zhang, Lihong Hu, Banglei Zhang, Chengting Zi, Xuanjun Wang, Jun Sheng.  (2019)  Interactions between β-cyclodextrin and tea catechins, and potential anti-osteoclastogenesis activity of the (−)-epigallocatechin-3-gallate–β-cyclodextrin complex.  RSC Advances,  (48): (28006-28018).  [PMID:35558992]
24. Lipeng Han, Qingna Lin, Guoqin Liu, Dongxue Han, Li Niu, Dongxiao Su.  (2019)  Inhibition Mechanism of Catechin, Resveratrol, Butylated Hydroxylanisole, and Tert-Butylhydroquinone on Carboxymethyl 1,2-Dipalmitoyl-sn-Glycero-3-Phosphatidylethanolamine Formation.  JOURNAL OF FOOD SCIENCE,  84  (8): (2042-2049).  [PMID:31313292]
25. Xiaqing Wu, Mingming Hu, Xing Hu, Huafang Ding, Deming Gong, Guowen Zhang.  (2019)  Inhibitory mechanism of epicatechin gallate on α-amylase and α-glucosidase and its combinational effect with acarbose or epigallocatechin gallate.  JOURNAL OF MOLECULAR LIQUIDS,  290  (111202).  [PMID:]
26. Qian Li, Chengmei Liu, Ti Li, David Julian McClements, Yinxin Fu, Jiyan Liu.  (2018)  Comparison of phytochemical profiles and antiproliferative activities of different proanthocyanidins fractions from Choerospondias axillaris fruit peels.  FOOD RESEARCH INTERNATIONAL,  113  (298).  [PMID:30195524]
27. Yongsheng Chen, Xiang Ma, Xiong Fu, Rian Yan.  (2017)  Phytochemical content, cellular antioxidant activity and antiproliferative activity of Adinandra nitida tea (Shiyacha) infusion subjected to in vitro gastrointestinal digestion.  RSC Advances,  (80): (50430-50440).  [PMID:]
28. Zaizhi Liu, Kailin Mo, Shimin Fei, Yuangang Zu, Lei Yang.  (2017)  Efficient approach for the extraction of proanthocyanidins from Cinnamomum longepaniculatum leaves using ultrasonic irradiation and an evaluation of their inhibition activity on digestive enzymes and antioxidant activity in vitro.  JOURNAL OF SEPARATION SCIENCE,  40  (15): (3100-3113).  [PMID:28590026]
29. Hua Dang, Donghong Liu, Xiangchang Hou, Yuluan Wu, Bin Wang, Hao Dong, Yanping Xian.  (2017)  One-step extraction prior to two-step detection by ultra high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) to determine different groups of antibacterial agents in infant disposable hygiene products.  Analytical Methods,  (3): (482-489).  [PMID:]
30. Meng Shi, Ying Nie, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye.  (2016)  Ultraviolet B (UVB) Photosensitivities of Tea Catechins and the Relevant Chemical Conversions.  MOLECULES,  21  (10): (1345).  [PMID:27735869]
31. Guobin Xia, Chunfang Lin, Songbai Liu.  (2016)  Tannase-mediated biotransformation assisted separation and purification of theaflavin and epigallocatechin by high speed counter current chromatography and preparative high performance liquid chromatography: A comparative study.  MICROSCOPY RESEARCH AND TECHNIQUE,  79  (9): (880-889).  [PMID:27389804]
32. Xu Huanhuan, Wang Ya, Chen Yana, Zhang Pan, Zhao Yi, Huang Yewei, Wang Xuanjun, Sheng Jun.  (2016)  Subcellular Localization of Galloylated Catechins in Tea Plants [Camellia sinensis (L.) O. Kuntze] Assessed via Immunohistochemistry.  Frontiers in Plant Science,    [PMID:27303422]
33. Qian Li, Xieyi Wang, Jun Chen, Chengmei Liu, Ti Li, David Julian McClements, Taotao Dai, Jiyan Liu.  (2016)  Antioxidant activity of proanthocyanidins-rich fractions from Choerospondias axillaris peels using a combination of chemical-based methods and cellular-based assay.  FOOD CHEMISTRY,  208  (309).  [PMID:27132855]
34. Fang-Yuan Fan, Meng Shi, Ying Nie, Yue Zhao, Jian-Hui Ye, Yue-Rong Liang.  (2016)  Differential behaviors of tea catechins under thermal processing: Formation of non-enzymatic oligomers.  FOOD CHEMISTRY,  196  (347).  [PMID:26593500]
35. Qian Li, Jun Chen, Ti Li, Chengmei Liu, Wei Liu, Jiyan Liu.  (2015)  Comparison of bioactivities and phenolic composition of Choerospondias axillaris peels and fleshes.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  96  (7): (2462-2471).  [PMID:26249806]
36. Lingnan Wang, Weiguang Ma, Shiyu Gan, Dongxue Han, Qixian Zhang, Li Niu.  (2014)  Engineered Photoelectrochemical Platform for Rational Global Antioxidant Capacity Evaluation Based on Ultrasensitive Sulfonated Graphene–TiO2 Nanohybrid.  ANALYTICAL CHEMISTRY,  86  (20): (10171–10178).  [PMID:25226344]
37. Guobin Xia, Shan Hong, Songbai Liu.  (2014)  Simultaneous preparation of naturally abundant and rare catechins by tannase-mediated biotransformation combining high speed counter current chromatography.  FOOD CHEMISTRY,  151  (380).  [PMID:24423547]
38. Chen Yulong, Duan Jun, Yang Shaoyu, Yang En, Jiang Yuming.  (2009)  Effect of Girdling on Levels of Catechins in Fresh Leaf in Relation to Quality of ‘Huang Zhi Xiang’ Oolong Tea.  PLANT FOODS FOR HUMAN NUTRITION,  64  (4): (293-296).  [PMID:19898938]
39. Qian Li,Jun Chen,Ti Li,Chengmei Liu,Yuxin Zhai,David Julian McClements,Jiyan Liu.  (2015-10-08)  Separation and characterization of polyphenolics from underutilized byproducts of fruit production (Choerospondias axillaris peels): inhibitory activity of proanthocyanidins against glycolysis enzymes..  Food & function,  ((12)): (3693-3701).  [PMID:26442714]
40. Liu, et al..  (2020)  Rapid Screening ?-Glucosidase Inhibitors from Natural Products by At-Line Nanofractionation with Parallel Mass Spectrometry and Bioactivity Assessment..  Journal of Chromatography A,  1635  (461740-461740).  [PMID:33271429]

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27. Yongsheng Chen, Xiang Ma, Xiong Fu, Rian Yan.  (2017)  Phytochemical content, cellular antioxidant activity and antiproliferative activity of Adinandra nitida tea (Shiyacha) infusion subjected to in vitro gastrointestinal digestion.  RSC Advances,  (80): (50430-50440).  [PMID:]
28. Zaizhi Liu, Kailin Mo, Shimin Fei, Yuangang Zu, Lei Yang.  (2017)  Efficient approach for the extraction of proanthocyanidins from Cinnamomum longepaniculatum leaves using ultrasonic irradiation and an evaluation of their inhibition activity on digestive enzymes and antioxidant activity in vitro.  JOURNAL OF SEPARATION SCIENCE,  40  (15): (3100-3113).  [PMID:28590026]
29. Hua Dang, Donghong Liu, Xiangchang Hou, Yuluan Wu, Bin Wang, Hao Dong, Yanping Xian.  (2017)  One-step extraction prior to two-step detection by ultra high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) to determine different groups of antibacterial agents in infant disposable hygiene products.  Analytical Methods,  (3): (482-489).  [PMID:]
30. Meng Shi, Ying Nie, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye.  (2016)  Ultraviolet B (UVB) Photosensitivities of Tea Catechins and the Relevant Chemical Conversions.  MOLECULES,  21  (10): (1345).  [PMID:27735869]
31. Guobin Xia, Chunfang Lin, Songbai Liu.  (2016)  Tannase-mediated biotransformation assisted separation and purification of theaflavin and epigallocatechin by high speed counter current chromatography and preparative high performance liquid chromatography: A comparative study.  MICROSCOPY RESEARCH AND TECHNIQUE,  79  (9): (880-889).  [PMID:27389804]
32. Xu Huanhuan, Wang Ya, Chen Yana, Zhang Pan, Zhao Yi, Huang Yewei, Wang Xuanjun, Sheng Jun.  (2016)  Subcellular Localization of Galloylated Catechins in Tea Plants [Camellia sinensis (L.) O. Kuntze] Assessed via Immunohistochemistry.  Frontiers in Plant Science,    [PMID:27303422]
33. Qian Li, Xieyi Wang, Jun Chen, Chengmei Liu, Ti Li, David Julian McClements, Taotao Dai, Jiyan Liu.  (2016)  Antioxidant activity of proanthocyanidins-rich fractions from Choerospondias axillaris peels using a combination of chemical-based methods and cellular-based assay.  FOOD CHEMISTRY,  208  (309).  [PMID:27132855]
34. Fang-Yuan Fan, Meng Shi, Ying Nie, Yue Zhao, Jian-Hui Ye, Yue-Rong Liang.  (2016)  Differential behaviors of tea catechins under thermal processing: Formation of non-enzymatic oligomers.  FOOD CHEMISTRY,  196  (347).  [PMID:26593500]
35. Qian Li, Jun Chen, Ti Li, Chengmei Liu, Wei Liu, Jiyan Liu.  (2015)  Comparison of bioactivities and phenolic composition of Choerospondias axillaris peels and fleshes.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  96  (7): (2462-2471).  [PMID:26249806]
36. Lingnan Wang, Weiguang Ma, Shiyu Gan, Dongxue Han, Qixian Zhang, Li Niu.  (2014)  Engineered Photoelectrochemical Platform for Rational Global Antioxidant Capacity Evaluation Based on Ultrasensitive Sulfonated Graphene–TiO2 Nanohybrid.  ANALYTICAL CHEMISTRY,  86  (20): (10171–10178).  [PMID:25226344]
37. Guobin Xia, Shan Hong, Songbai Liu.  (2014)  Simultaneous preparation of naturally abundant and rare catechins by tannase-mediated biotransformation combining high speed counter current chromatography.  FOOD CHEMISTRY,  151  (380).  [PMID:24423547]
38. Chen Yulong, Duan Jun, Yang Shaoyu, Yang En, Jiang Yuming.  (2009)  Effect of Girdling on Levels of Catechins in Fresh Leaf in Relation to Quality of ‘Huang Zhi Xiang’ Oolong Tea.  PLANT FOODS FOR HUMAN NUTRITION,  64  (4): (293-296).  [PMID:19898938]
39. Qian Li,Jun Chen,Ti Li,Chengmei Liu,Yuxin Zhai,David Julian McClements,Jiyan Liu.  (2015-10-08)  Separation and characterization of polyphenolics from underutilized byproducts of fruit production (Choerospondias axillaris peels): inhibitory activity of proanthocyanidins against glycolysis enzymes..  Food & function,  ((12)): (3693-3701).  [PMID:26442714]
40. Liu, et al..  (2020)  Rapid Screening ?-Glucosidase Inhibitors from Natural Products by At-Line Nanofractionation with Parallel Mass Spectrometry and Bioactivity Assessment..  Journal of Chromatography A,  1635  (461740-461740).  [PMID:33271429]

Solution Calculators