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Eplerenone - ≥98%, high purity , Mineralocorticoid receptor antagonist, CAS No.107724-20-9, Mineralocorticoid receptor antagonist

Specifications & Purity:  ≥98%
Item Number
E129934
Grouped product items
SKUSizeAvailabilityPrice Qty
E129934-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$86.90
E129934-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$255.90
E129934-200mg
200mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$921.90
E129934-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,036.90
E129934-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$3,732.90
E129934-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$16,796.90

Selective mineralocorticoid antagonist

Basic Description

SynonymsEplerenone|107724-20-9|Epoxymexrenone|Inspra|Selara|SC-66110|Cgp 30083|CGP-30083|HSDB 7522|DTXSID2046094|UNII-6995V82D0B|CHEBI:31547|SC-6611O|6995V82D0B|SC 6110|CHEMBL1095097|DTXCID0026094|9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dic
Specifications & Purity≥98%
Storage TempStore at 2-8°C
Shipped InWet ice
Action TypeANTAGONIST
Mechanism of actionMineralocorticoid receptor antagonist

Product Properties

ALogP1.4

Associated Targets

NR3C2 Tclin Mineralocorticoid receptor 3 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name methyl (1R,2S,9R,10R,11S,14R,15S,17R)-2,15-dimethyl-5,5'-dioxospiro[18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-ene-14,2'-oxolane]-9-carboxylate
INCHI InChI=1S/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,21+,22+,23-,24-/m1/s1
InChi Key JUKPWJGBANNWMW-VWBFHTRKSA-N
Canonical SMILES CC12CCC(=O)C=C1CC(C3C24C(O4)CC5(C3CCC56CCC(=O)O6)C)C(=O)OC
Isomeric SMILES C[C@]12CCC(=O)C=C1C[C@H]([C@@H]3[C@]24[C@H](O4)C[C@]5([C@H]3CC[C@@]56CCC(=O)O6)C)C(=O)OC
WGK Germany 3
PubChem CID 443872
Molecular Weight 414.49

Certificates

Certificate of Analysis(COA)

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7 results found

Lot NumberCertificate TypeDateItem
F2125305Certificate of AnalysisApr 13, 2023 E129934
F2125254Certificate of AnalysisApr 13, 2023 E129934
F2125249Certificate of AnalysisApr 13, 2023 E129934
F2125250Certificate of AnalysisApr 13, 2023 E129934
F2125255Certificate of AnalysisApr 13, 2023 E129934
F2125259Certificate of AnalysisApr 13, 2023 E129934
G1520066Certificate of AnalysisFeb 03, 2023 E129934

Chemical and Physical Properties

SolubilitySoluble in DMSO (10 mM), water (very slightly), ethanol (slightly), methanol (sparingly), and chloroform.
SensitivityHeat sensitive
Melt Point(°C)242 °C(dec.)

Safety and Hazards(GHS)

Related Documents

Solution Calculators