Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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E129934-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $86.90 | |
E129934-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $255.90 | |
E129934-200mg | 200mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $921.90 | |
E129934-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,036.90 | |
E129934-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $3,732.90 | |
E129934-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $16,796.90 |
Selective mineralocorticoid antagonist
Synonyms | Eplerenone|107724-20-9|Epoxymexrenone|Inspra|Selara|SC-66110|Cgp 30083|CGP-30083|HSDB 7522|DTXSID2046094|UNII-6995V82D0B|CHEBI:31547|SC-6611O|6995V82D0B|SC 6110|CHEMBL1095097|DTXCID0026094|9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dic |
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Specifications & Purity | ≥98% |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Action Type | ANTAGONIST |
Mechanism of action | Mineralocorticoid receptor antagonist |
ALogP | 1.4 |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | methyl (1R,2S,9R,10R,11S,14R,15S,17R)-2,15-dimethyl-5,5'-dioxospiro[18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-ene-14,2'-oxolane]-9-carboxylate |
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INCHI | InChI=1S/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,21+,22+,23-,24-/m1/s1 |
InChi Key | JUKPWJGBANNWMW-VWBFHTRKSA-N |
Canonical SMILES | CC12CCC(=O)C=C1CC(C3C24C(O4)CC5(C3CCC56CCC(=O)O6)C)C(=O)OC |
Isomeric SMILES | C[C@]12CCC(=O)C=C1C[C@H]([C@@H]3[C@]24[C@H](O4)C[C@]5([C@H]3CC[C@@]56CCC(=O)O6)C)C(=O)OC |
WGK Germany | 3 |
PubChem CID | 443872 |
Molecular Weight | 414.49 |
PubChem CID | 443872 |
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DrugBank Ligand | DB00700 |
BindingDB Ligand | 50324120 |
CAS Registry No. | 107724-20-9 |
ChEBI | CHEBI:31547 |
Wikipedia | Eplerenone |
ChEMBL Ligand | CHEMBL1095097 |
PEP | eplerenone |
RCSB PDB Ligand | YNU, YNU |
DrugCentral Ligand | 1032 |
Enter Lot Number to search for COA:
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Lot Number | Certificate Type | Date | Item |
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Certificate of Analysis | Apr 13, 2023 | E129934 | |
Certificate of Analysis | Apr 13, 2023 | E129934 | |
Certificate of Analysis | Apr 13, 2023 | E129934 | |
Certificate of Analysis | Apr 13, 2023 | E129934 | |
Certificate of Analysis | Apr 13, 2023 | E129934 | |
Certificate of Analysis | Apr 13, 2023 | E129934 | |
Certificate of Analysis | Feb 03, 2023 | E129934 |
Solubility | Soluble in DMSO (10 mM), water (very slightly), ethanol (slightly), methanol (sparingly), and chloroform. |
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Sensitivity | Heat sensitive |
Melt Point(°C) | 242 °C(dec.) |
Pictogram(s) | GHS08,GHS07 |
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Signal | Warning |
Hazard Statements | H373,H413,H302,H317,H312,H332,H361 |
Precautionary Statements | P261,P273,P280,P302+P352,P321,P405,P501,P264,P260,P271,P270,P304+P340,P272,P333+P313,P362+P364,P330,P203,P301+P317,P318,P317,P319 |
WGK Germany | 3 |
Merck Index | 3625 |