Eplivanserin (mixture) - 99%, high purity , Serotonin 2a (5-HT2a) receptor antagonist, CAS No.130581-13-4, Serotonin 2a (5-HT2a) receptor antagonist

  • ≥99%
Item Number
E650786
Grouped product items
SKUSizeAvailabilityPrice Qty
E650786-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$55.90
E650786-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$90.90
E650786-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$250.90
E650786-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$350.90

Basic Description

SynonymsEplivanserin | 130579-75-8 | SR-46349 | SR46349 | 130581-13-4 | 3CO94WO6DJ | 4-[(E,3Z)-3-[2-(dimethylamino)ethoxyimino]-3-(2-fluorophenyl)prop-1-enyl]phenol | (E)-1-(2-fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime | SR46349B | Eplivanseri
Specifications & Purity≥99%
Biochemical and Physiological MechanismsEplivanserin mixture (SR-46349 mixture) is a selective serotonin reuptake inhibitor and a 5-HT 2A receptor antagonist, extracted from patent WO 2005/002578 A1.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Action TypeANTAGONIST
Mechanism of actionSerotonin 2a (5-HT2a) receptor antagonist
Product Description

Eplivanserin mixture (SR-46349 mixture) is a selective serotonin reuptake inhibitor and a 5-HT 2A receptor antagonist, extracted from patent WO 2005/002578 A1

Form:Solid

IC50& Target:5-HT 2A Receptor

Associated Targets(Human)

HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Htr2b Serotonin 2 (5-HT2) receptor (2078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 4-[(E,3Z)-3-[2-(dimethylamino)ethoxyimino]-3-(2-fluorophenyl)prop-1-enyl]phenol
INCHI InChI=1S/C19H21FN2O2/c1-22(2)13-14-24-21-19(17-5-3-4-6-18(17)20)12-9-15-7-10-16(23)11-8-15/h3-12,23H,13-14H2,1-2H3/b12-9+,21-19-
InChi Key VAIOZOCLKVMIMN-PRJWTAEASA-N
Canonical SMILES CN(C)CCON=C(C=CC1=CC=C(C=C1)O)C2=CC=CC=C2F
Isomeric SMILES CN(C)CCO/N=C(/C=C/C1=CC=C(C=C1)O)\C2=CC=CC=C2F
Alternate CAS 130579-75-8
PubChem CID 135456190
MeSH Entry Terms 4-((3Z)-3-(2-dimethylaminoethyl)oxyimino-3-(2-fluorophenyl)propen-1-yl)phenol hemifumarate;SR 46349;SR 46349B;SR-46349;SR-46349B
Molecular Weight 328.38

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 125 mg/mL (380.66 mM; Need ultrasonic)

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Solution Calculators