Click Here for 5% Off Your First Aladdin Purchase!
Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

Erastin - ≥99%, high purity , CAS No.571203-78-6

Specifications & Purity:  ≥99%
Item Number
E126853
Grouped product items
SKUSizeAvailabilityPrice Qty
E126853-5mg
5mg
In stock
$112.90
E126853-25mg
25mg
In stock
$508.90
E126853-100mg
100mg
In stock
$1,830.90
E126853-500mg
500mg
In stock
$8,237.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET

Selective ferrotopsis activator

Basic Description

SynonymsERASTIN|571203-78-6|2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone|2-(1-(4-(2-(4-chlorophenoxy)acetyl)piperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one|MFCD09837984|2-[1-[4-[2-(4-chlorophenoxy)ac
Specifications & Purity≥99%
Storage TempStore at -20°C,Argon charged
Shipped InDry ice

Associated Targets

SLC7A11 Tchem Cystine/glutamate transporter 3 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

VDAC2 Tchem Voltage-dependent anion-selective channel protein 2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-[1-[4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one
INCHI InChI=1S/C30H31ClN4O4/c1-3-38-27-11-7-6-10-26(27)35-29(32-25-9-5-4-8-24(25)30(35)37)21(2)33-16-18-34(19-17-33)28(36)20-39-23-14-12-22(31)13-15-23/h4-15,21H,3,16-20H2,1-2H3
InChi Key BKQFRNYHFIQEKN-UHFFFAOYSA-N
Canonical SMILES CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl
Isomeric SMILES CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl
WGK Germany 3
PubChem CID 11214940
Molecular Weight 547.04

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

13 results found

Lot NumberCertificate TypeDateItem
C2426003Certificate of AnalysisAug 10, 2023 E126853
H2328430Certificate of AnalysisAug 10, 2023 E126853
H2328431Certificate of AnalysisAug 10, 2023 E126853
H2328432Certificate of AnalysisAug 10, 2023 E126853
L2205441Certificate of AnalysisNov 22, 2022 E126853
L2205572Certificate of AnalysisNov 22, 2022 E126853
L2205573Certificate of AnalysisNov 22, 2022 E126853
L2205576Certificate of AnalysisNov 22, 2022 E126853
F2209101Certificate of AnalysisMay 19, 2022 E126853
F2209128Certificate of AnalysisMay 19, 2022 E126853
F2209175Certificate of AnalysisMay 19, 2022 E126853
F2209177Certificate of AnalysisMay 19, 2022 E126853
C2221030Certificate of AnalysisMar 24, 2022 E126853

more

Chemical and Physical Properties

Solubility25°C: DMSO
Sensitivityair ＆ heat sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS06
Signal Danger
Hazard Statements H301
Precautionary Statements P321,P405,P501,P264,P270,P330,P301+P316
WGK Germany 3

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. Erastin
    Erastin

    Starting at $241.90

FAQs and Articles

FAQ
Targeted drug discovery: scarce and inefficient, what is the geometry of its effectiveness?
Categories: Technical articles
Tags:
Targeted drug Drug discovery Discovery origin Target-based drug Phenotype-based drugs

Product Questions

Product Questions

Sign In Hover me Please sign in to submit a question
See all
No questions yet. Be the first to ask the question!

Reviews

Customer Reviews

References

1. Torii S et al..  (2016)  An essential role for functional lysosomes in ferroptosis of cancer cells..  Biochem J,      [PMID:26759376]
2. Chen L et al..  (2021)  Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas..  Front Immunol,  12  (739039).  [PMID:35185859]
3. Xie Y et al..  (2016)  Ferroptosis: process and function..  Cell Death Differ,      [PMID:26794443]
4. Simamura E et al..  (2008)  Mitochondrial voltage-dependent anion channels (VDACs) as novel pharmacological targets for anti-cancer agents..  J Bioenerg Biomembr,  40  (3): (213-7).  [PMID:18704666]
5. Haß C et al..  (2016)  Sensitization of acute lymphoblastic leukemia cells for LCL161-induced cell death by targeting redox homeostasis..  Biochem Pharmacol,      [PMID:26774450]

Calculator

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.