Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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E105721-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $12.90 | |
E105721-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $47.90 | |
E105721-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $168.90 | |
E105721-100g | 100g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $605.90 |
Synonyms | 14-((2E)(1R,4R)-1,4,5-trimethylhex-2-enyl)(1S,5S,2R,11R,14R,15R)-2,15-dimethyl tetracyclo[8.7.0.0<2,7>.0<11,15>]heptadeca-7,9-dien-5-ol | SCHEMBL43194 | Provitamin D 2 | Radia 7363 | Ergosta-5,7,22-trien-3-ol, (3b,22E)- | CCRIS 7220 | Q143263 | Z30RAY509F |
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Specifications & Purity | ≥95% |
Biochemical and Physiological Mechanisms | Ergosterol has a role in maintaining the integrity of the cell membrane and its fluidity. The sterol has anti-tumor and anti-inflammatory properties. |
Storage Temp | Protected from light,Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Product Description | Dihexadecyl phosphate (DHP) is a negatively charged lipid that is used for the formation of model membranes. product description: Ergosterol or provitamin D2 is a biological precursor of Vitamin D2. It is found predominantly in cell membranes of fungi and protists such as trypanosomes. application: Ergosterol has been used: as a component of yeast cell monolayer models, to study the effects of steroidal and triterpenoid saponins on the monolayers as a standard sample, to isolate and identify a fungal metabolite fraction containing ergosterol as a component of the culture medium to isolate the CYP51RNAi phenotype of Trypanosoma brucei gambiense, to verify ergosterol biosynthesis |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (3S,9S,10R,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol |
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INCHI | InChI=1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1 |
InChi Key | DNVPQKQSNYMLRS-APGDWVJJSA-N |
Canonical SMILES | CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2=CC=C4C3(CCC(C4)O)C)C |
Isomeric SMILES | C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3C2=CC=C4[C@@]3(CC[C@@H](C4)O)C)C |
WGK Germany | 3 |
PubChem CID | 444679 |
UN Number | 2811 |
Molecular Weight | 396.65 |
Beilstein | 2338604 |
Reaxy-Rn | 2338604 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
E2306195 | Certificate of Analysis | May 09, 2023 | E105721 |
E2306196 | Certificate of Analysis | May 09, 2023 | E105721 |
J2220196 | Certificate of Analysis | Oct 26, 2022 | E105721 |
J2220197 | Certificate of Analysis | Oct 26, 2022 | E105721 |
J2220199 | Certificate of Analysis | Oct 26, 2022 | E105721 |
J2220208 | Certificate of Analysis | Oct 26, 2022 | E105721 |
Solubility | insoluble in DMSO; insoluble in EtOH; insoluble in H2O |
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Sensitivity | Sensitive to humidity, heat, air, and light |
Specific Rotation[α] | -112.5 ° (C=1, THF) |
Boil Point(°C) | 250°C |
Melt Point(°C) | 156-158°C |
Pictogram(s) | GHS06 |
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Signal | Danger |
Hazard Statements | H413:May cause long lasting harmful effects to aquatic life H300:Fatal if swallowed |
Precautionary Statements | P273:Avoid release to the environment. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
WGK Germany | 3 |
Reaxy-Rn | 2338604 |
Merck Index | 3659 |
1. Yuhong Chen, Ying Gao, Mingan Yuan, Zhaisheng Zheng, Junfeng Yin. (2023) Anti-Candida albicans Effects and Mechanisms of Theasaponin E1 and Assamsaponin A. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (11): (9350). [PMID:37298302] [10.3390/ijms24119350] |
2. Zhonghua Dong, Xiao Sun. (2023) Chemical components in artificial Cordyceps sinensis and their effects on fibrosis. Chinese Herbal Medicines, [PMID:38375041] [10.1016/j.chmed.2022.11.008] |
3. Han Wu, Hao-Nan Liu, Ai-Min Ma, Jian-Zhong Zhou, Xiu-Dong Xia. (2022) Synergetic effects of Lactobacillus plantarum and Rhizopus oryzae on physicochemical, nutritional and antioxidant properties of whole-grain oats (Avena sativa L.) during solid-state fermentation. LWT-FOOD SCIENCE AND TECHNOLOGY, 154 (112687). [PMID:] [10.1016/j.lwt.2021.112687] |
4. Xin Yang, Zejun Pei, Renjing Hu, Zhehao Zhang, Zaixiang Lou, Xin Sun. (2021) Study on the Inhibitory Activity and Possible Mechanism of Myriocin on Clinically Relevant Drug-Resistant Candida albicans and Its Biofilms. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 44 (3): (305-315). [PMID:33441497] [10.1248/bpb.b20-00246] |
5. Zhifeng Cai, Liangliang Wu, Jierui Xi, Erxiao Hao, Kaifei Qi. (2021) Green and facile synthesis of polyethyleneimine-protected fluorescent silver nanoclusters for the highly specific biosensing of curcumin. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 615 (126228). [PMID:] [10.1016/j.colsurfa.2021.126228] |
6. Dong Zhonghua, Iqbal Sajid, Zhao Zhongxi. (2020) Preparation of Ergosterol-Loaded Nanostructured Lipid Carriers for Enhancing Oral Bioavailability and Antidiabetic Nephropathy Effects. AAPS PHARMSCITECH, 21 (2): (1-11). [PMID:31932990] [10.1208/s12249-019-1597-3] |
7. Sun Xiao, Feng Xiuli, Zheng Dandan, Li Ang, Li Chunyan, Li Siying, Zhao Zhongxi. (2019) Ergosterol attenuates cigarette smoke extract-induced COPD by modulating inflammation, oxidative stress and apoptosis in vitro and in vivo. CLINICAL SCIENCE, 133 (13): (1523-1536). [PMID:31270147] [10.1042/CS20190331] |
8. Jin-Xiu Liang, Qun-Qun Zhang, Yan-Fei Huang, Han-Qing Pang, Xin-Guang Liu, Wen Gao, Ping Li, Hua Yang. (2019) Comprehensive chemical profiling of monascus-fermented rice product and screening of lipid-lowering compounds other than monacolins. JOURNAL OF ETHNOPHARMACOLOGY, 238 (111879). [PMID:30991138] [10.1016/j.jep.2019.111879] |
9. Kedong Tai, Fuguo Liu, Xiaoye He, Peihua Ma, Like Mao, Yanxiang Gao, Fang Yuan. (2018) The effect of sterol derivatives on properties of soybean and egg yolk lecithin liposomes: Stability, structure and membrane characteristics. FOOD RESEARCH INTERNATIONAL, 109 (24). [PMID:29803447] [10.1016/j.foodres.2018.04.014] |
10. Fang Fang, Bingye Dai, Guang Zhao, Hua Zhao, Chao Sun, Hui Liu, Mo Xian. (2016) In depth understanding the molecular response to the enhanced secretion of fatty acids in Saccharomyces cerevisiae due to one-step gene deletion of acyl-CoA synthetases. PROCESS BIOCHEMISTRY, 51 (1162). [PMID:] [10.1016/j.procbio.2016.05.017] |
11. Cheng Zhengjun. (2012) Interaction of ergosterol with bovine serum albumin and human serum albumin by spectroscopic analysis. MOLECULAR BIOLOGY REPORTS, 39 (10): (9493-9508). [PMID:22733490] [10.1007/s11033-012-1814-6] |
12. Zhuomin Zhang, Wei Tan, Yuling Hu, Gongke Li. (2011) Simultaneous determination of trace sterols in complicated biological samples by gas chromatography–mass spectrometry coupled with extraction using β-sitosterol magnetic molecularly imprinted polymer beads. JOURNAL OF CHROMATOGRAPHY A, 1218 (4275). [PMID:21632061] [10.1016/j.chroma.2011.05.022] |
13. Hui Wang, Jin Qi, Tian Xu, Ji-Hua Liu, Min-Jian Qin, Dan-Ni Zhu, Bo-Yang Yu. (2010) Effects of Storage Condition Factors on Fungal Invasion of Radix Ophiopogonis. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 58 (9): (5432–5437). [PMID:20397649] [10.1021/jf9044588] |
14. Jianbin Ye,Zhan Zhang,Ji Yan,Hui Hao,Xiangzhen Liu,Zongcan Yang,Ke Ma,Xuepeng Yang,Duobin Mao,Hao Zhou. (2016-12-14) Degradation of phytosterols in tobacco waste extract by a novel Paenibacillus sp.. Biotechnology and applied biochemistry, 64 ((6)): (843-850). [PMID:27958658] |
1. Yuhong Chen, Ying Gao, Mingan Yuan, Zhaisheng Zheng, Junfeng Yin. (2023) Anti-Candida albicans Effects and Mechanisms of Theasaponin E1 and Assamsaponin A. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (11): (9350). [PMID:37298302] [10.3390/ijms24119350] |
2. Zhonghua Dong, Xiao Sun. (2023) Chemical components in artificial Cordyceps sinensis and their effects on fibrosis. Chinese Herbal Medicines, [PMID:38375041] [10.1016/j.chmed.2022.11.008] |
3. Han Wu, Hao-Nan Liu, Ai-Min Ma, Jian-Zhong Zhou, Xiu-Dong Xia. (2022) Synergetic effects of Lactobacillus plantarum and Rhizopus oryzae on physicochemical, nutritional and antioxidant properties of whole-grain oats (Avena sativa L.) during solid-state fermentation. LWT-FOOD SCIENCE AND TECHNOLOGY, 154 (112687). [PMID:] [10.1016/j.lwt.2021.112687] |
4. Xin Yang, Zejun Pei, Renjing Hu, Zhehao Zhang, Zaixiang Lou, Xin Sun. (2021) Study on the Inhibitory Activity and Possible Mechanism of Myriocin on Clinically Relevant Drug-Resistant Candida albicans and Its Biofilms. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 44 (3): (305-315). [PMID:33441497] [10.1248/bpb.b20-00246] |
5. Zhifeng Cai, Liangliang Wu, Jierui Xi, Erxiao Hao, Kaifei Qi. (2021) Green and facile synthesis of polyethyleneimine-protected fluorescent silver nanoclusters for the highly specific biosensing of curcumin. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 615 (126228). [PMID:] [10.1016/j.colsurfa.2021.126228] |
6. Dong Zhonghua, Iqbal Sajid, Zhao Zhongxi. (2020) Preparation of Ergosterol-Loaded Nanostructured Lipid Carriers for Enhancing Oral Bioavailability and Antidiabetic Nephropathy Effects. AAPS PHARMSCITECH, 21 (2): (1-11). [PMID:31932990] [10.1208/s12249-019-1597-3] |
7. Sun Xiao, Feng Xiuli, Zheng Dandan, Li Ang, Li Chunyan, Li Siying, Zhao Zhongxi. (2019) Ergosterol attenuates cigarette smoke extract-induced COPD by modulating inflammation, oxidative stress and apoptosis in vitro and in vivo. CLINICAL SCIENCE, 133 (13): (1523-1536). [PMID:31270147] [10.1042/CS20190331] |
8. Jin-Xiu Liang, Qun-Qun Zhang, Yan-Fei Huang, Han-Qing Pang, Xin-Guang Liu, Wen Gao, Ping Li, Hua Yang. (2019) Comprehensive chemical profiling of monascus-fermented rice product and screening of lipid-lowering compounds other than monacolins. JOURNAL OF ETHNOPHARMACOLOGY, 238 (111879). [PMID:30991138] [10.1016/j.jep.2019.111879] |
9. Kedong Tai, Fuguo Liu, Xiaoye He, Peihua Ma, Like Mao, Yanxiang Gao, Fang Yuan. (2018) The effect of sterol derivatives on properties of soybean and egg yolk lecithin liposomes: Stability, structure and membrane characteristics. FOOD RESEARCH INTERNATIONAL, 109 (24). [PMID:29803447] [10.1016/j.foodres.2018.04.014] |
10. Fang Fang, Bingye Dai, Guang Zhao, Hua Zhao, Chao Sun, Hui Liu, Mo Xian. (2016) In depth understanding the molecular response to the enhanced secretion of fatty acids in Saccharomyces cerevisiae due to one-step gene deletion of acyl-CoA synthetases. PROCESS BIOCHEMISTRY, 51 (1162). [PMID:] [10.1016/j.procbio.2016.05.017] |
11. Cheng Zhengjun. (2012) Interaction of ergosterol with bovine serum albumin and human serum albumin by spectroscopic analysis. MOLECULAR BIOLOGY REPORTS, 39 (10): (9493-9508). [PMID:22733490] [10.1007/s11033-012-1814-6] |
12. Zhuomin Zhang, Wei Tan, Yuling Hu, Gongke Li. (2011) Simultaneous determination of trace sterols in complicated biological samples by gas chromatography–mass spectrometry coupled with extraction using β-sitosterol magnetic molecularly imprinted polymer beads. JOURNAL OF CHROMATOGRAPHY A, 1218 (4275). [PMID:21632061] [10.1016/j.chroma.2011.05.022] |
13. Hui Wang, Jin Qi, Tian Xu, Ji-Hua Liu, Min-Jian Qin, Dan-Ni Zhu, Bo-Yang Yu. (2010) Effects of Storage Condition Factors on Fungal Invasion of Radix Ophiopogonis. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 58 (9): (5432–5437). [PMID:20397649] [10.1021/jf9044588] |
14. Jianbin Ye,Zhan Zhang,Ji Yan,Hui Hao,Xiangzhen Liu,Zongcan Yang,Ke Ma,Xuepeng Yang,Duobin Mao,Hao Zhou. (2016-12-14) Degradation of phytosterols in tobacco waste extract by a novel Paenibacillus sp.. Biotechnology and applied biochemistry, 64 ((6)): (843-850). [PMID:27958658] |