Grouped product items

SKU

Size

Availability

Price

Qty

E105721-1g

Available within 4-8 weeks(?)

$12.90

E105721-5g

Available within 4-8 weeks(?)

$47.90

E105721-25g

25g

Available within 4-8 weeks(?)

$168.90

E105721-100g

100g

Available within 4-8 weeks(?)

$605.90

Basic Description

Synonyms	14-((2E)(1R,4R)-1,4,5-trimethylhex-2-enyl)(1S,5S,2R,11R,14R,15R)-2,15-dimethyl tetracyclo[8.7.0.0<2,7>.0<11,15>]heptadeca-7,9-dien-5-ol \| SCHEMBL43194 \| Provitamin D 2 \| Radia 7363 \| Ergosta-5,7,22-trien-3-ol, (3b,22E)- \| CCRIS 7220 \| Q143263 \| Z30RAY509F
Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	Ergosterol has a role in maintaining the integrity of the cell membrane and its fluidity. The sterol has anti-tumor and anti-inflammatory properties.
Storage Temp	Protected from light,Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	Dihexadecyl phosphate (DHP) is a negatively charged lipid that is used for the formation of model membranes. product description： Ergosterol or provitamin D2 is a biological precursor of Vitamin D2. It is found predominantly in cell membranes of fungi and protists such as trypanosomes. application： Ergosterol has been used: as a component of yeast cell monolayer models, to study the effects of steroidal and triterpenoid saponins on the monolayers as a standard sample, to isolate and identify a fungal metabolite fraction containing ergosterol as a component of the culture medium to isolate the CYP51RNAi phenotype of Trypanosoma brucei gambiense, to verify ergosterol biosynthesis

Associated Targets(Human)

GAPDH Tchem Glyceraldehyde-3-phosphate dehydrogenase liver (1284 Activities)

Discover Target: GAPDH

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COLO 205 (50209 Activities)

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COLO 320 (353 Activities)

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MRC5 (9203 Activities)

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A549 (127892 Activities)

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NCI-H157 (619 Activities)

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HepG2 (196354 Activities)

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HeLa (62764 Activities)

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UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 (448 Activities)

Discover Target: UGT1A1

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

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HSPA5 Tchem 78 kDa glucose-regulated protein (3319 Activities)

Discover Target: HSPA5

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HSPA1A Tchem Heat shock 70 kDa protein 1A/1B (2 Activities)

Discover Target: HSPA1A

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TPM1 Tbio Tropomyosin alpha-1 chain (2 Activities)

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TPM4 Tbio Tropomyosin alpha-4 chain (3 Activities)

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ECH1 Tbio Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (3 Activities)

Discover Target: ECH1

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Associated Targets(non-human)

Abcb1b P-glycoprotein 1 (174 Activities)

Discover Target: Abcb1b

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Nos2 Nitric oxide synthase, inducible (3573 Activities)

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Hdac6 Histone deacetylase 6 (222 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Legionella pneumophila (143 Activities)

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Salmonella typhimurium (15756 Activities)

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Staphylococcus aureus (210822 Activities)

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Escherichia coli (133304 Activities)

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Salmonella typhi (4293 Activities)

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Bacillus subtilis (32866 Activities)

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Mycobacterium tuberculosis (203094 Activities)

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Saccharomyces cerevisiae (19171 Activities)

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Enterococcus faecalis (29875 Activities)

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Priestia megaterium (1154 Activities)

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Spinacia oleracea (250 Activities)

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Pichia kudriavzevii (7448 Activities)

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Penicillium chrysogenum (1593 Activities)

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Microbotryum violaceum (192 Activities)

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Candida albicans (78123 Activities)

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L5178Y (1809 Activities)

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PC-12 (7051 Activities)

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RAW264.7 (28094 Activities)

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BV-2 (3710 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

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Mycolicibacterium vaccae (371 Activities)

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Sporobolomyces salmonicolor (103 Activities)

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Dpysl2 Dihydropyrimidinase-related protein 2 (10 Activities)

Discover Target: Dpysl2

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HSPA8 Heat shock cognate 71 kDa protein (1 Activities)

Discover Target: HSPA8

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Goffeauzyma gastrica (7 Activities)

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SARS-CoV-2 (38078 Activities)

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Names and Identifiers

IUPAC Name	(3S,9S,10R,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
INCHI	InChI=1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1
InChi Key	DNVPQKQSNYMLRS-APGDWVJJSA-N
Canonical SMILES	CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2=CC=C4C3(CCC(C4)O)C)C
Isomeric SMILES	C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3C2=CC=C4[C@@]3(CC[C@@H](C4)O)C)C
WGK Germany	3
PubChem CID	444679
UN Number	2811
Molecular Weight	396.65
Beilstein	2338604
Reaxy-Rn	2338604

Certificates

Certificate of Analysis(COA)

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Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
E2306195	Certificate of Analysis	May 09, 2023	E105721
E2306196	Certificate of Analysis	May 09, 2023	E105721
J2220196	Certificate of Analysis	Oct 26, 2022	E105721
J2220197	Certificate of Analysis	Oct 26, 2022	E105721
J2220199	Certificate of Analysis	Oct 26, 2022	E105721
J2220208	Certificate of Analysis	Oct 26, 2022	E105721

Chemical and Physical Properties

Solubility	insoluble in DMSO; insoluble in EtOH; insoluble in H2O
Sensitivity	Sensitive to humidity, heat, air, and light
Specific Rotation[α]	-112.5 ° (C=1, THF)
Boil Point(°C)	250°C
Melt Point(°C)	156-158°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06
Signal	Danger
Hazard Statements	H413:May cause long lasting harmful effects to aquatic life H300:Fatal if swallowed
Precautionary Statements	P273:Avoid release to the environment. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately.
WGK Germany	3
Reaxy-Rn	2338604
Merck Index	3659

Citations of This Product

1. Yuhong Chen, Ying Gao, Mingan Yuan, Zhaisheng Zheng, Junfeng Yin. (2023) Anti-Candida albicans Effects and Mechanisms of Theasaponin E1 and Assamsaponin A. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (11): (9350). [PMID:37298302]
2. Zhonghua Dong, Xiao Sun. (2023) Chemical components in artificial Cordyceps sinensis and their effects on fibrosis. Chinese Herbal Medicines, [PMID:38375041]
3. Han Wu, Hao-Nan Liu, Ai-Min Ma, Jian-Zhong Zhou, Xiu-Dong Xia. (2022) Synergetic effects of Lactobacillus plantarum and Rhizopus oryzae on physicochemical, nutritional and antioxidant properties of whole-grain oats (Avena sativa L.) during solid-state fermentation. LWT-FOOD SCIENCE AND TECHNOLOGY, 154 (112687). [PMID:]
4. Jianbin Ye,Zhan Zhang,Ji Yan,Hui Hao,Xiangzhen Liu,Zongcan Yang,Ke Ma,Xuepeng Yang,Duobin Mao,Hao Zhou. (2016-12-14) Degradation of phytosterols in tobacco waste extract by a novel Paenibacillus sp.. Biotechnology and applied biochemistry, 64 ((6)): (843-850). [PMID:27958658]

References

1. Yuhong Chen, Ying Gao, Mingan Yuan, Zhaisheng Zheng, Junfeng Yin. (2023) Anti-Candida albicans Effects and Mechanisms of Theasaponin E1 and Assamsaponin A. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (11): (9350). [PMID:37298302]
2. Zhonghua Dong, Xiao Sun. (2023) Chemical components in artificial Cordyceps sinensis and their effects on fibrosis. Chinese Herbal Medicines, [PMID:38375041]
3. Han Wu, Hao-Nan Liu, Ai-Min Ma, Jian-Zhong Zhou, Xiu-Dong Xia. (2022) Synergetic effects of Lactobacillus plantarum and Rhizopus oryzae on physicochemical, nutritional and antioxidant properties of whole-grain oats (Avena sativa L.) during solid-state fermentation. LWT-FOOD SCIENCE AND TECHNOLOGY, 154 (112687). [PMID:]
4. Jianbin Ye,Zhan Zhang,Ji Yan,Hui Hao,Xiangzhen Liu,Zongcan Yang,Ke Ma,Xuepeng Yang,Duobin Mao,Hao Zhou. (2016-12-14) Degradation of phytosterols in tobacco waste extract by a novel Paenibacillus sp.. Biotechnology and applied biochemistry, 64 ((6)): (843-850). [PMID:27958658]

Solution Calculators

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Ergosterol - 95%, high purity , CAS No.57-87-4

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
E105721-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$12.90
E105721-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$47.90
E105721-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$168.90
E105721-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$605.90