Basic Description

Synonyms	7-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one;hydrate \| MLS002695944 \| CHEBI:73111 \| AKOS025310104 \| Esculetin-6-beta-D-glucopyranoside \| CCG-207863 \| Esculin Sesquihydrate min. 97.5%, DAB, for biochemistry \| M
Specifications & Purity	for microbiology
Storage Temp	Room temperature
Shipped In	Normal
Grade	for microbiology

Associated Targets(Human)

ERAP2 Tchem Endoplasmic reticulum aminopeptidase 2 (387 Activities)

Discover Target: ERAP2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ERAP1 Tchem Endoplasmic reticulum aminopeptidase 1 (581 Activities)

Discover Target: ERAP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ATXN2 Tbio Ataxin-2 (54410 Activities)

Discover Target: ATXN2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	7-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one;hydrate
INCHI	InChI=1S/C15H16O9.H2O/c16-5-10-12(19)13(20)14(21)15(24-10)23-9-3-6-1-2-11(18)22-8(6)4-7(9)17;/h1-4,10,12-17,19-21H,5H2;1H2/t10-,12-,13+,14-,15-;/m1./s1
InChi Key	CQYPGSKIFJFVDQ-QWFKVUSTSA-N
Canonical SMILES	C1=CC(=O)OC2=CC(=C(C=C21)OC3C(C(C(C(O3)CO)O)O)O)O.O
Isomeric SMILES	C1=CC(=O)OC2=CC(=C(C=C21)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O.O
Alternate CAS	531-75-9
PubChem CID	16211025
Molecular Weight	367.31

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot Number	Certificate Type	Date	Item
F2328995	Certificate of Analysis	Jun 15, 2023	E433254

Chemical and Physical Properties

Melt Point(°C)	204-206°C

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Yong-Yu Yang, Jing-Jing Qi, Si-Yi Jiang, Ling Ye. (2023) Esculin ameliorates obesity-induced insulin resistance by improving adipose tissue remodeling and activating the IRS1/PI3K/AKT/GLUT4 pathway. JOURNAL OF ETHNOPHARMACOLOGY, (6): (117251). [PMID:37778516] [10.1016/j.jep.2023.117251]
2. Jiangwei Ni, Ge Li, Ningfeng Dai, Zijiao Quan, Haibin Tong, Yu Liu. (2023) Esculin alleviates LPS-induced acute lung injury via inhibiting neutrophil recruitment and migration. INTERNATIONAL IMMUNOPHARMACOLOGY, 119 (110177). [PMID:37068336] [10.1016/j.intimp.2023.110177]

References

1. Yong-Yu Yang, Jing-Jing Qi, Si-Yi Jiang, Ling Ye. (2023) Esculin ameliorates obesity-induced insulin resistance by improving adipose tissue remodeling and activating the IRS1/PI3K/AKT/GLUT4 pathway. JOURNAL OF ETHNOPHARMACOLOGY, (6): (117251). [PMID:37778516] [10.1016/j.jep.2023.117251]
2. Jiangwei Ni, Ge Li, Ningfeng Dai, Zijiao Quan, Haibin Tong, Yu Liu. (2023) Esculin alleviates LPS-induced acute lung injury via inhibiting neutrophil recruitment and migration. INTERNATIONAL IMMUNOPHARMACOLOGY, 119 (110177). [PMID:37068336] [10.1016/j.intimp.2023.110177]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Esculin - suitable for microbiology, high purity , CAS No.66778-17-4