Esculin hydrate - 98%, high purity , CAS No.531-75-9

  • ≥98%
Item Number
E107333
Grouped product items
SKUSizeAvailabilityPrice Qty
E107333-1g
1g
In stock
$20.90
E107333-5g
5g
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$80.90
E107333-25g
25g
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$363.90
E107333-100g
100g
In stock
$1,308.90

Antioxidant. Plant coumarin glucoside.

Basic Description

Synonyms2H-1-Benzopyran-2-one, 6-(beta-D-glucopyranosyloxy)-7-hydroxy- | AKOS015895151 | SR-01000633930-1 | Z1494829512 | aesculin | CAS-531-75-9 | 7-hydroxy-2-oxo-2H-chromen-6-yl beta-D-glucopyranoside | C09264 | DTXCID5025318 | 7-hydroxy-6-(((2S,3R,4S,5S,6R)-3,
Specifications & Purity≥98%
Biochemical and Physiological MechanismsAntioxidant and plant coumarin glucoside. Exerts SOD-mimetic effects and reduces superoxide radicals generation. Inhibitory effects of chemically induced oxidative DNA damage and carcinogenesis in vivo.
Shipped InNormal
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Product Introduction

Esculin hydrate has vasoprotective and venotonic properties.


Application

Esculin hydrate has been used as a component of sporulation-inducing esculin agar. It has also been used for esculin uptake assay.

Associated Targets(Human)

MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MIF Tchem Macrophage migration inhibitory factor (979 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLA Tclin Alpha-galactosidase A (5444 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CASP1 Tchem Caspase-1 (6235 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CASP7 Tchem Caspase-7 (3146 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TAS2R16 Tchem Taste receptor type 2 member 16 (102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
dsDNA (365 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
quadruplex DNA (2700 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

pol Human immunodeficiency virus type 1 reverse transcriptase (18245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cruzipain (33337 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pol Human immunodeficiency virus type 1 integrase (9041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
C6 (2371 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Impa1 Inositol monophosphatase 1 (16203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488195236
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488195236
IUPAC Name 7-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one
INCHI InChI=1S/C15H16O9/c16-5-10-12(19)13(20)14(21)15(24-10)23-9-3-6-1-2-11(18)22-8(6)4-7(9)17/h1-4,10,12-17,19-21H,5H2/t10-,12-,13+,14-,15-/m1/s1
InChi Key XHCADAYNFIFUHF-TVKJYDDYSA-N
Canonical SMILES C1=CC(=O)OC2=CC(=C(C=C21)OC3C(C(C(C(O3)CO)O)O)O)O
Isomeric SMILES C1=CC(=O)OC2=CC(=C(C=C21)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O
RTECS DJ3085000
PubChem CID 5281417
Molecular Weight 340.28(anhydrous)
Beilstein 18(3/4)1326
Reaxy-Rn 95387

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
C1922108Certificate of AnalysisJan 12, 2023 E107333
L2213132Certificate of AnalysisOct 20, 2022 E107333
L2213143Certificate of AnalysisOct 20, 2022 E107333
L2213161Certificate of AnalysisOct 20, 2022 E107333
L2213163Certificate of AnalysisOct 20, 2022 E107333
L2213173Certificate of AnalysisOct 20, 2022 E107333
L2213342Certificate of AnalysisOct 20, 2022 E107333
L2213356Certificate of AnalysisOct 20, 2022 E107333
L2213378Certificate of AnalysisOct 20, 2022 E107333

Chemical and Physical Properties

Specific Rotation[α]-79 ° (C=2.4, 50% Dioxane)
Melt Point(°C)203-205°C

Safety and Hazards(GHS)

RTECS DJ3085000
Reaxy-Rn 95387
Merck Index 3698

Related Documents

Citations of This Product

1. Yin Lu, Yuan Zhang, Kan Zhang.  (2022)  Renewable biomass resources to access halogen- and phosphorus-free flame retardant thermosets with ultra-low heat release capacity.  CHEMICAL ENGINEERING JOURNAL,  448  (137670).  [PMID:] [10.1016/j.cej.2022.137670]
2. Lizhen Chen, Jie Wu, Feng Yan, Huangxian Ju.  (2021)  A facile strategy for quantitative sensing of glycans on cell surface using organic electrochemical transistors.  BIOSENSORS & BIOELECTRONICS,  175  (112878).  [PMID:33298337] [10.1016/j.bios.2020.112878]
3. Yuanyang Dong, Qihang Hou, Meng Sun, Jingjing Sun, Bingkun Zhang.  (2020)  Targeted Isolation of Antioxidant Constituents from Plantago asiatica L. and In Vitro Activity Assay.  MOLECULES,  25  (8): (1825).  [PMID:32316264] [10.3390/molecules25081825]

References

1. Yin Lu, Yuan Zhang, Kan Zhang.  (2022)  Renewable biomass resources to access halogen- and phosphorus-free flame retardant thermosets with ultra-low heat release capacity.  CHEMICAL ENGINEERING JOURNAL,  448  (137670).  [PMID:] [10.1016/j.cej.2022.137670]
2. Lizhen Chen, Jie Wu, Feng Yan, Huangxian Ju.  (2021)  A facile strategy for quantitative sensing of glycans on cell surface using organic electrochemical transistors.  BIOSENSORS & BIOELECTRONICS,  175  (112878).  [PMID:33298337] [10.1016/j.bios.2020.112878]
3. Yuanyang Dong, Qihang Hou, Meng Sun, Jingjing Sun, Bingkun Zhang.  (2020)  Targeted Isolation of Antioxidant Constituents from Plantago asiatica L. and In Vitro Activity Assay.  MOLECULES,  25  (8): (1825).  [PMID:32316264] [10.3390/molecules25081825]

Solution Calculators