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Esculin sesquihydrate - 98%, high purity , CAS No.66778-17-4

2 Citations
  • ≥98%
Item Number
E103661
Grouped product items
SKUSizeAvailabilityPrice Qty
E103661-1g
1g
In stock
$15.90
E103661-5g
5g
In stock
$42.90
E103661-25g
25g
In stock
$147.90
E103661-100g
100g
In stock
$479.90
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View related series
Coumarins Natural glycosides

Basic Description

Synonyms7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate | 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one hydrate
Specifications & Purity≥98%
Storage TempProtected from light
Shipped InNormal

Associated Targets(Human)

ERAP2 Tchem Endoplasmic reticulum aminopeptidase 2 (387 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERAP1 Tchem Endoplasmic reticulum aminopeptidase 1 (581 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATXN2 Tbio Ataxin-2 (54410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488199074
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488199074
IUPAC Name 7-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one;hydrate
INCHI InChI=1S/C15H16O9.H2O/c16-5-10-12(19)13(20)14(21)15(24-10)23-9-3-6-1-2-11(18)22-8(6)4-7(9)17;/h1-4,10,12-17,19-21H,5H2;1H2/t10-,12-,13+,14-,15-;/m1./s1
InChi Key CQYPGSKIFJFVDQ-QWFKVUSTSA-N
Canonical SMILES C1=CC(=O)OC2=CC(=C(C=C21)OC3C(C(C(C(O3)CO)O)O)O)O.O
Isomeric SMILES C1=CC(=O)OC2=CC(=C(C=C21)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O.O
Alternate CAS 531-75-9
PubChem CID 16211025
Molecular Weight 367.31

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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24 results found

Lot NumberCertificate TypeDateItem
L2403616Certificate of AnalysisNov 21, 2024 E103661
L2403615Certificate of AnalysisNov 21, 2024 E103661
I2426192Certificate of AnalysisSep 18, 2024 E103661
I2426191Certificate of AnalysisSep 18, 2024 E103661
I2426190Certificate of AnalysisSep 18, 2024 E103661
G2423360Certificate of AnalysisJul 15, 2024 E103661
K2329407Certificate of AnalysisNov 20, 2023 E103661
K2329405Certificate of AnalysisNov 20, 2023 E103661
K2329392Certificate of AnalysisNov 20, 2023 E103661
K2329393Certificate of AnalysisNov 20, 2023 E103661
K2320211Certificate of AnalysisNov 09, 2023 E103661
K2320217Certificate of AnalysisNov 09, 2023 E103661
F2327769Certificate of AnalysisMay 30, 2023 E103661
F2327778Certificate of AnalysisMay 30, 2023 E103661
F2327845Certificate of AnalysisMay 30, 2023 E103661
F2327848Certificate of AnalysisMay 30, 2023 E103661
F2327856Certificate of AnalysisMay 30, 2023 E103661
F2327590Certificate of AnalysisMay 05, 2023 E103661
B2215260Certificate of AnalysisDec 28, 2021 E103661
B2215261Certificate of AnalysisDec 28, 2021 E103661
D2310299Certificate of AnalysisDec 28, 2021 E103661
D2310320Certificate of AnalysisDec 28, 2021 E103661
D2310321Certificate of AnalysisDec 28, 2021 E103661
B2215245Certificate of AnalysisDec 28, 2021 E103661

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Chemical and Physical Properties

SensitivityMoisture sensitive.
Melt Point(°C)204-206°C

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. Esculin sesquihydrate - analytical standard，>99.9%(HPLC), used for , CAS No. 66778-17-4, by Aladdin Scientific
    Esculin sesquihydrate

    Starting at $102.90

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Yong-Yu Yang, Jing-Jing Qi, Si-Yi Jiang, Ling Ye.  (2023)  Esculin ameliorates obesity-induced insulin resistance by improving adipose tissue remodeling and activating the IRS1/PI3K/AKT/GLUT4 pathway.  JOURNAL OF ETHNOPHARMACOLOGY,    (6): (117251).  [PMID:37778516] [10.1016/j.jep.2023.117251]
2. Jiangwei Ni, Ge Li, Ningfeng Dai, Zijiao Quan, Haibin Tong, Yu Liu.  (2023)  Esculin alleviates LPS-induced acute lung injury via inhibiting neutrophil recruitment and migration.  INTERNATIONAL IMMUNOPHARMACOLOGY,  119  (110177).  [PMID:37068336] [10.1016/j.intimp.2023.110177]

References

1. Yong-Yu Yang, Jing-Jing Qi, Si-Yi Jiang, Ling Ye.  (2023)  Esculin ameliorates obesity-induced insulin resistance by improving adipose tissue remodeling and activating the IRS1/PI3K/AKT/GLUT4 pathway.  JOURNAL OF ETHNOPHARMACOLOGY,    (6): (117251).  [PMID:37778516] [10.1016/j.jep.2023.117251]
2. Jiangwei Ni, Ge Li, Ningfeng Dai, Zijiao Quan, Haibin Tong, Yu Liu.  (2023)  Esculin alleviates LPS-induced acute lung injury via inhibiting neutrophil recruitment and migration.  INTERNATIONAL IMMUNOPHARMACOLOGY,  119  (110177).  [PMID:37068336] [10.1016/j.intimp.2023.110177]

Solution Calculators

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