Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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E336532-1mg | 1mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $209.90 | |
E336532-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $940.90 | |
E336532-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,692.90 | |
E336532-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $3,809.90 | |
E336532-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $6,856.90 | |
E336532-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $12,341.90 |
a potent inhibitor of ES
Synonyms | BDBM50134329 | 1,8-dihydroxy-anthraquinone | 17-Oxoestra-1,3,5(10)-triene-3-yl Sulfamate | DAC 893 | Estrone-3-O-sulfamate | estrone3-O-sulfamate | Estrone 3-O-Sulfamate | RVKFQAJIXCZXQY-CBZIJGRNSA-N | SCHEMBL305660 | Sulfamic acid (8R,9S,13S,14S)-13-meth |
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Specifications & Purity | ≥97% |
Storage Temp | Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Product Description | Estrone 3-O-Sulfamate is a potent inhibitor of ES (estrone sulfatase). Estrone 3-O-Sulfamate inhibits estrone sulfatase >99% at 0.1μM in intact MCF-7 cells, IC|50|=65pM. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | [(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] sulfamate |
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INCHI | InChI=1S/C18H23NO4S/c1-18-9-8-14-13-5-3-12(23-24(19,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16H,2,4,6-9H2,1H3,(H2,19,21,22)/t14-,15-,16+,18+/m1/s1 |
InChi Key | RVKFQAJIXCZXQY-CBZIJGRNSA-N |
Canonical SMILES | CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)N |
Isomeric SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)N |
PubChem CID | 127676 |
Molecular Weight | 349.44 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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H2231494 | Certificate of Analysis | Aug 15, 2022 | E336532 |
H2231495 | Certificate of Analysis | Aug 15, 2022 | E336532 |
H2231496 | Certificate of Analysis | Aug 15, 2022 | E336532 |
H2231497 | Certificate of Analysis | Aug 15, 2022 | E336532 |
H2231498 | Certificate of Analysis | Aug 15, 2022 | E336532 |
H2231499 | Certificate of Analysis | Aug 15, 2022 | E336532 |
Solubility | Soluble in DMSO and Methanol |
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Sensitivity | Hygroscopic |
Melt Point(°C) | 195-197°C (lit.) |