Ethidium bromide(EB) - ≥95% (HPLC), high purity , CAS No.1239-45-8

  • ≥95%(HPLC)
Item Number
E109020
Grouped product items
SKUSizeAvailabilityPrice Qty
E109020-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$22.90
E109020-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$47.90
E109020-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$547.90

Intercalating fluorescent dye reagent for DNA/RNA staining

View related series
Spectroscopic reagent

Basic Description

SynonymsEB | EtBr | 2,7-Diamino-10-ethyl-9-phenylphenanthridinium bromide | CCG-39365 | CS-0009917 | Dromilac | Phenanthridinium, 3,8-diamino-5-ethyl-6-phenyl-, bromide (1:1) | UNII-059NUO2Z1L | Homidium bromide | RD 1572 | Ethidium bromide, ~95% (HPLC) | NCGC000
Specifications & Purity≥95%(HPLC)
Biochemical and Physiological MechanismsEthidium bromide intercalates double-stranded DNA and RNA and acts as a frameshift mutagen. It can also be used in conjunction with acridine orange to differentiate between viable, apoptotic and necrotic cells.Intercalates double-stranded DNA and RNA. Bou
Shipped InNormal
Note200mg售完停产,不再备货Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

For staining a gel after electrophoresis, dilute a sample of the stock solution to 0.5 μg/ml with water and incubate the gel for 15-30 min. Destaining is usually not needed but can be carried out in water for 15 min if decreased background is necessary. The DNA bands can then be detected on a UV light box (254 nm wavelength). Ethidium bromide can also be incorporated into the gel and running buffer at 0.5 μg/ml and visualized immediately after electrophoresis.
Ethidium bromide is an aromatic cationic dye, is one of the most studied DNA-intercalating agents and has been used widely as a molecular probe. It is also used in the prophylaxis and treatment of animal trypanosomiasis in affected areas worldwide.

Associated Targets(Human)

ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TOP1 Tclin DNA topoisomerase I (7553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TOP2A Tclin DNA topoisomerase II alpha (6317 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TNF Tclin TNF-alpha (1897 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLA Tclin Alpha-galactosidase A (5444 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR1H4 Tclin Bile acid receptor FXR (6228 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit (1459 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CASP1 Tchem Caspase-1 (6235 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CASP7 Tchem Caspase-7 (3146 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TERT Tchem Telomerase reverse transcriptase (2428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A498 (42825 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHN (49357 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CAKI-1 (44928 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCRF-CEM (65223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
COLO 205 (50209 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DU-145 (51482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
K562 (73714 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KM12 (47707 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
M14 (47487 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MOLT-4 (49676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-3 (48710 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-4 (44535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-5 (45555 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-8 (47708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RPMI-8226 (44974 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXF 393 (41971 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SF-295 (48000 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-2 (46422 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-28 (48833 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-5 (47095 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-OV-3 (52876 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SN12C (47755 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNB-19 (46794 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

pol Human immunodeficiency virus type 1 reverse transcriptase (18245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
gag-pol Moloney murine leukaemia virus Pol protein (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Top2 DNA topoisomerase II (15 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus pneumoniae (31063 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterobacter cloacae (7976 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pasteurella multocida (1166 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Neisseria meningitidis (411 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella enteritidis (727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium avium (4587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycolicibacterium smegmatis (8003 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hepatitis C virus (23859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHO (4503 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
H9c2 (3506 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NIH3T3 (5395 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferase (58 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Calf thymus DNA (4845 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmon testes DNA (254 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fadD28 Acyl-CoA synthase (418 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mitf Microphthalmia-associated transcription factor (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
mdtK Multidrug resistance protein mdtK (13 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor (6467 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
vpr Aberrant vpr protein (14595 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
groL GroEL/GroES (1042 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
groEL 60 kDa chaperonin (64 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 5-ethyl-6-phenylphenanthridin-5-ium-3,8-diamine;bromide
INCHI InChI=1S/C21H19N3.BrH/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14;/h3-13,23H,2,22H2,1H3;1H
InChi Key ZMMJGEGLRURXTF-UHFFFAOYSA-N
Canonical SMILES CC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N.[Br-]
Isomeric SMILES CC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N.[Br-]
WGK Germany 3
RTECS SF7950000
PubChem CID 14710
Molecular Weight 394.32

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
K2419503Certificate of AnalysisApr 25, 2024 E109020
B2225193Certificate of AnalysisDec 12, 2023 E109020
B2225209Certificate of AnalysisDec 12, 2023 E109020
B2225215Certificate of AnalysisDec 12, 2023 E109020
C2405102Certificate of AnalysisDec 12, 2023 E109020
C2405106Certificate of AnalysisDec 12, 2023 E109020
H2126091Certificate of AnalysisJun 05, 2023 E109020
B2102137Certificate of AnalysisDec 12, 2022 E109020
H2311051Certificate of AnalysisDec 10, 2021 E109020

Chemical and Physical Properties

Melt Point(°C)260-262°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08
Signal Danger
Hazard Statements

H341:Suspected of causing genetic defects

H302:Harmful if swallowed

H330:Fatal if inhaled

Precautionary Statements

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P281:Use personal protective equipment as required.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P330:Rinse mouth.

P320:Specific treatment is urgent (see ... on this label).

P203:Obtain, read and follow all safety instructions before use.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

P316:Get emergency medical help immediately.

WGK Germany 3
RTECS SF7950000
Merck Index 4731

Related Documents

Citations of This Product

1. Yu Cao, Yiming Zhang, Chengyu Han, Shuo Liu, Shaojie Zhang, Xinyi Liu, Baoshan Zhang, Fusheng Pan, Jie Sun.  (2023)  Zwitterionic Covalent Organic Framework Based Electrostatic Field Electrocatalysts for Durable Lithium–Sulfur Batteries.  ACS Nano,  17  (22): (22632–22641).  [PMID:37933557]
2. Jian Sun, Huayi Qu, Waseem Ali, Yan Chen, Tao Wang, Yonggang Ma, Yan Yuan, Jianhong Gu, Jianchun Bian, Zongping Liu, Hui Zou.  (2023)  Co-exposure to cadmium and microplastics promotes liver fibrosis through the hemichannels -ATP-P2X7 pathway.  CHEMOSPHERE,    (17): (140372).  [PMID:37802476]
3. Yufang Li, Xiaozhao Tang, Zushun Yang, Jinze He, Ni Ma, Aixiang Huang, Yanan Shi.  (2023)  BCp12/PLA combination: A novel antibacterial agent targeting Mur family, DNA gyrase and DHFR.  INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY,  406  (110370).  [PMID:37678070]
4. Xiaolong Peng, Qiang Tang, Huiyun Zhu, Lijuan Bai, Hua Zhao, Yongjie Chen.  (2023)  Study on antitumor activity of three ruthenium arene complexes in vitro.  JOURNAL OF INORGANIC BIOCHEMISTRY,  247  (112310).  [PMID:37441921]
5. Ji Ma, Guoxia Huang, Changxin Mo, Junsheng Li, Liujuan Yan, Qian Zhang.  (2023)  Insights into the intercalative binding of benzo[b]fluoranthene with herring sperm DNA in vitro and its application.  JOURNAL OF MOLECULAR LIQUIDS,  378  (121628).  [PMID:]
6. Zhixiao Liu, Zhiming Mi, Lingjun Meng, Yangyang Huang, Dexing Zhang, Junman Wang, Kaiyang Zhang, Jingling Xiao, Pingli Liu, Zhi Rao, Hongru He, Shuai Wang.  (2023)  Quaternary ammonium salts modification preparing charged Janus nanofiltration membrane for the simultaneous separation of divalent anions and cations.  JOURNAL OF MEMBRANE SCIENCE,  672  (121440).  [PMID:]
7. Jing Yang, Wen Ting Wang, Zheng Dou Shi, Rui Yang, Xia Li Liao, Bo Yang, Chuan Zhu Gao.  (2022)  Phosphorescent cyclometalated iridium(III) complexes with mono-, di-, and tetranuclear as two channel probes to light up the nuclei of living cells.  APPLIED ORGANOMETALLIC CHEMISTRY,  37  (2): (e6964).  [PMID:]
8. Juan Wu, Xi Wang, Binglong Zhu, Qinting He, Yaheng Zhang, Wei Jiang.  (2022)  Synthesis and characterization of magnetic polymeric nanocomposites for pH-sensitive controlled release of methotrexate.  JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,      [PMID:35727073]
9. Lujun Yin, Ping-Ping Zhang, Wei Wang, Shi Tang, Shi-Ming Deng, Ai-Qun Jia.  (2022)  3-Phenylpropan-1-Amine Enhanced Susceptibility of Serratia marcescens to Ofloxacin by Occluding Quorum Sensing.  Microbiology Spectrum,      [PMID:35972277]
10. Liangping Li, Pingping Li, Xuesong Ma, Shulan Zeng, Yan Peng, Guohai Zhang.  (2022)  Therapeutic restoring p53 function with small molecule for oncogene-driven non-small cell lung cancer by targeting serine 392 phosphorylation.  BIOCHEMICAL PHARMACOLOGY,  203  (115188).  [PMID:35902040]
11. Wei-Hao Wu, Xiao-Mei Ma, Jian-Qing Huang, Qin Lai, Fu-Neng Jiang, Cui-Yun Zou, Long-Tian Chen, Lian Yu.  (2022)  CRISPR/Cas9 (D10A) nickase-mediated Hb CS gene editing and genetically modified fibroblast identification.  Bioengineered,  13  (5): (13398-13406).  [PMID:36700476]
12. Lihua Chen, Pan Zhao, Jing Yang, Xiali Liao, Bo Yang, Chuanzhu Gao.  (2022)  Synthesis, characterization, and antitumor biological evaluation of novel fluorine-containing platinum (IV) complexes.  APPLIED ORGANOMETALLIC CHEMISTRY,  36  (7): (e6759).  [PMID:]
13. Huang Yiqian, Du Zhiyun, Li Ke, Jing Wei, Wei Pengfei, Zhao Bo, Yu Yingjie, Cai Qing, Yang Xiaoping.  (2022)  ROS-Scavenging Electroactive Polyphosphazene-Based Core–Shell Nanofibers for Bone Regeneration.  Advanced Fiber Materials,  (4): (894-907).  [PMID:]
14. Haolu Hu, Xiaoxia Kang, Zhenhua Shan, Xiaoxiao Yang, Wei Bing, Li Wu, Haiyan Ge, Haiwei Ji.  (2022)  A DNase-mimetic artificial enzyme for the eradication of drug-resistant bacterial biofilm infections.  Nanoscale,  14  (7): (2676-2685).  [PMID:35107481]
15. Jinmin Wang, Xin Xu, Limin Zhao, Bing Yan.  (2021)  In situ growth of polyoxometalate in COF for trace monitoring of Ag+ and hepatocellular carcinoma biomarker via a dual responsive strategy.  Journal of Materials Chemistry C,  (30): (9492-9498).  [PMID:]
16. Feng Xiao, Jiayu Liu, Yongbo Zheng, Zhen Quan, Wei Sun, Yao Fan, Chunli Luo, Hailiang Li, Xiaohou Wu.  (2020)  The targeted inhibition of prostate cancer by iron-based nanoparticles based on bioinformatics.  JOURNAL OF BIOMATERIALS APPLICATIONS,      [PMID:33283584]
17. Zhaohui Chen, Shuihua Wu.  (2020)  Protective Effects of SIRT6 Against Inflammation, Oxidative Stress, and Cell Apoptosis in Spinal Cord Injury.  INFLAMMATION,  43  (5): (1751-1758).  [PMID:32445068]
18. Kaiyao Shi, Yang Liu, Jingru Ma, Yuqing Zhao, Liang Liu, Jingying Wang.  (2020)  A series of aromatric-amine-cored fluorescent emitters for amplified spontaneous laser emission and emission turn-on sensing.  JOURNAL OF LUMINESCENCE,  223  (117165).  [PMID:]
19. Zeng Xin, Zhu Min, Liu Xiaohong, Chen Xuanmin, Yuan Yujia, Li Lan, Liu Jingping, Lu Yanrong, Cheng Jingqiu, Chen Younan.  (2020)  Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis.  Nutrition & Metabolism,  17  (1): (1-14).  [PMID:32021639]
20. Haixia Liu, Qingzhu Yang, Wei Guo, Huiming Lin, Feng Zhang, Jingxiang Zhao, Tianyue Ma, Le Zhao, Na Xu, Ruiwen Wang, Jingyao Yu, Fengyu Qu.  (2020)  CoWO4-x-based nanoplatform for multimode imaging and enhanced photothermal/photodynamic therapy.  CHEMICAL ENGINEERING JOURNAL,  385  (123979).  [PMID:]
21. Yun Li, Yueqin Li, Nana Wang, Dong Lin, Xiaohui Liu, Yong Yang, Qinwei Gao.  (2020)  Synthesis, DNA/BSA binding studies and in vitro biological assay of nickel(II) complexes incorporating tridentate aroylhydrazone and triphenylphosphine ligands.  JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS,  38  (17): (4977-4996).  [PMID:31739745]
22. Haiming Yu, Yuefei Wang, Xiaoqing Wang, Junjie Guo, Hui Wang, Hao Zhang, Fengxia Du.  (2019)  Jatrorrhizine suppresses the antimicrobial resistance of methicillin‑resistant Staphylococcus aureus.  Experimental and Therapeutic Medicine,  18  (5): (3715-3722).  [PMID:31616505]
23. Rui Wang, Xing Hu, Junhui Pan, Guowen Zhang, Deming Gong.  (2019)  Interaction of isoeugenol with calf thymus DNA and its protective effect on DNA oxidative damage.  JOURNAL OF MOLECULAR LIQUIDS,  282  (356).  [PMID:]
24. Zhisheng Zhou, Xing Hu, Guowen Zhang, Rui Wang, Deming Gong.  (2019)  Exploring the binding interaction of Maillard reaction by-product 5-hydroxymethyl-2-furaldehyde with calf thymus DNA.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  99  (6): (3192-3202).  [PMID:30548611]
25. Xunan Jing, Zhe Zhi, Daquan Wang, Jing Liu, Yongping Shao, Lingjie Meng.  (2018)  Multifunctional Nanoflowers for Simultaneous Multimodal Imaging and High-Sensitivity Chemo-Photothermal Treatment.  BIOCONJUGATE CHEMISTRY,  29  (2): (559–570).  [PMID:29376319]
26. Shi-Ying Li, Hong Cheng, Bo-Ru Xie, Wen-Xiu Qiu, Chu-Xin Li, Bin Li, Han Cheng, Xian-Zheng Zhang.  (2017)  Mitochondria targeted cancer therapy using ethidium derivatives.  Materials Today Chemistry,  (34).  [PMID:]
27. Ramachandran Vinayagam, Baojun Xu.  (2017)  7, 8-Dihydroxycoumarin (daphnetin) protects INS-1 pancreatic β-cells against streptozotocin-induced apoptosis.  PHYTOMEDICINE,  24  (119).  [PMID:28160851]
28. Juan Wu, Wei Jiang, Yewen Shen, Wei Jiang, Renbing Tian.  (2017)  Synthesis and characterization of mesoporous magnetic nanocomposites wrapped with chitosan gatekeepers for pH-sensitive controlled release of doxorubicin.  Materials Science & Engineering C-Materials for Biological Applications,  70  (132).  [PMID:27770872]
29. Zhaohui Yang, Min Li, Mingda Yu, Jing Huang, Haiyin Xu, Yan Zhou, Peipei Song, Rui Xu.  (2016)  A novel approach for methylene blue removal by calcium dodecyl sulfate enhanced precipitation and microbial flocculant GA1 flocculation.  CHEMICAL ENGINEERING JOURNAL,  303  (1).  [PMID:]
30. Hailiang Huang, Shuo Shi, Xuyue Zheng, Tianming Yao.  (2015)  Sensitive detection for coralyne and mercury ions based on homo-A/T DNA by exonuclease signal amplification.  BIOSENSORS & BIOELECTRONICS,  71  (439).  [PMID:25950941]
31. Jinhua Zhu, Lanlan Chen, Yingying Dong, Jiazhong Li, Xiuhua Liu.  (2014)  Spectroscopic and molecular modeling methods to investigate the interaction between 5-Hydroxymethyl-2-furfural and calf thymus DNA using ethidium bromide as a probe.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  124  (78).  [PMID:24463243]

References

1. Yin X et al..  (2018)  Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone..  J Neuroinflammation,  15  (97).  [PMID:29587860]
2. Yu Cao, Yiming Zhang, Chengyu Han, Shuo Liu, Shaojie Zhang, Xinyi Liu, Baoshan Zhang, Fusheng Pan, Jie Sun.  (2023)  Zwitterionic Covalent Organic Framework Based Electrostatic Field Electrocatalysts for Durable Lithium–Sulfur Batteries.  ACS Nano,  17  (22): (22632–22641).  [PMID:37933557]
3. Jian Sun, Huayi Qu, Waseem Ali, Yan Chen, Tao Wang, Yonggang Ma, Yan Yuan, Jianhong Gu, Jianchun Bian, Zongping Liu, Hui Zou.  (2023)  Co-exposure to cadmium and microplastics promotes liver fibrosis through the hemichannels -ATP-P2X7 pathway.  CHEMOSPHERE,    (17): (140372).  [PMID:37802476]
4. Yufang Li, Xiaozhao Tang, Zushun Yang, Jinze He, Ni Ma, Aixiang Huang, Yanan Shi.  (2023)  BCp12/PLA combination: A novel antibacterial agent targeting Mur family, DNA gyrase and DHFR.  INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY,  406  (110370).  [PMID:37678070]
5. Xiaolong Peng, Qiang Tang, Huiyun Zhu, Lijuan Bai, Hua Zhao, Yongjie Chen.  (2023)  Study on antitumor activity of three ruthenium arene complexes in vitro.  JOURNAL OF INORGANIC BIOCHEMISTRY,  247  (112310).  [PMID:37441921]
6. Ji Ma, Guoxia Huang, Changxin Mo, Junsheng Li, Liujuan Yan, Qian Zhang.  (2023)  Insights into the intercalative binding of benzo[b]fluoranthene with herring sperm DNA in vitro and its application.  JOURNAL OF MOLECULAR LIQUIDS,  378  (121628).  [PMID:]
7. Zhixiao Liu, Zhiming Mi, Lingjun Meng, Yangyang Huang, Dexing Zhang, Junman Wang, Kaiyang Zhang, Jingling Xiao, Pingli Liu, Zhi Rao, Hongru He, Shuai Wang.  (2023)  Quaternary ammonium salts modification preparing charged Janus nanofiltration membrane for the simultaneous separation of divalent anions and cations.  JOURNAL OF MEMBRANE SCIENCE,  672  (121440).  [PMID:]
8. Jing Yang, Wen Ting Wang, Zheng Dou Shi, Rui Yang, Xia Li Liao, Bo Yang, Chuan Zhu Gao.  (2022)  Phosphorescent cyclometalated iridium(III) complexes with mono-, di-, and tetranuclear as two channel probes to light up the nuclei of living cells.  APPLIED ORGANOMETALLIC CHEMISTRY,  37  (2): (e6964).  [PMID:]
9. Juan Wu, Xi Wang, Binglong Zhu, Qinting He, Yaheng Zhang, Wei Jiang.  (2022)  Synthesis and characterization of magnetic polymeric nanocomposites for pH-sensitive controlled release of methotrexate.  JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,      [PMID:35727073]
10. Lujun Yin, Ping-Ping Zhang, Wei Wang, Shi Tang, Shi-Ming Deng, Ai-Qun Jia.  (2022)  3-Phenylpropan-1-Amine Enhanced Susceptibility of Serratia marcescens to Ofloxacin by Occluding Quorum Sensing.  Microbiology Spectrum,      [PMID:35972277]
11. Liangping Li, Pingping Li, Xuesong Ma, Shulan Zeng, Yan Peng, Guohai Zhang.  (2022)  Therapeutic restoring p53 function with small molecule for oncogene-driven non-small cell lung cancer by targeting serine 392 phosphorylation.  BIOCHEMICAL PHARMACOLOGY,  203  (115188).  [PMID:35902040]
12. Wei-Hao Wu, Xiao-Mei Ma, Jian-Qing Huang, Qin Lai, Fu-Neng Jiang, Cui-Yun Zou, Long-Tian Chen, Lian Yu.  (2022)  CRISPR/Cas9 (D10A) nickase-mediated Hb CS gene editing and genetically modified fibroblast identification.  Bioengineered,  13  (5): (13398-13406).  [PMID:36700476]
13. Lihua Chen, Pan Zhao, Jing Yang, Xiali Liao, Bo Yang, Chuanzhu Gao.  (2022)  Synthesis, characterization, and antitumor biological evaluation of novel fluorine-containing platinum (IV) complexes.  APPLIED ORGANOMETALLIC CHEMISTRY,  36  (7): (e6759).  [PMID:]
14. Huang Yiqian, Du Zhiyun, Li Ke, Jing Wei, Wei Pengfei, Zhao Bo, Yu Yingjie, Cai Qing, Yang Xiaoping.  (2022)  ROS-Scavenging Electroactive Polyphosphazene-Based Core–Shell Nanofibers for Bone Regeneration.  Advanced Fiber Materials,  (4): (894-907).  [PMID:]
15. Haolu Hu, Xiaoxia Kang, Zhenhua Shan, Xiaoxiao Yang, Wei Bing, Li Wu, Haiyan Ge, Haiwei Ji.  (2022)  A DNase-mimetic artificial enzyme for the eradication of drug-resistant bacterial biofilm infections.  Nanoscale,  14  (7): (2676-2685).  [PMID:35107481]
16. Jinmin Wang, Xin Xu, Limin Zhao, Bing Yan.  (2021)  In situ growth of polyoxometalate in COF for trace monitoring of Ag+ and hepatocellular carcinoma biomarker via a dual responsive strategy.  Journal of Materials Chemistry C,  (30): (9492-9498).  [PMID:]
17. Feng Xiao, Jiayu Liu, Yongbo Zheng, Zhen Quan, Wei Sun, Yao Fan, Chunli Luo, Hailiang Li, Xiaohou Wu.  (2020)  The targeted inhibition of prostate cancer by iron-based nanoparticles based on bioinformatics.  JOURNAL OF BIOMATERIALS APPLICATIONS,      [PMID:33283584]
18. Zhaohui Chen, Shuihua Wu.  (2020)  Protective Effects of SIRT6 Against Inflammation, Oxidative Stress, and Cell Apoptosis in Spinal Cord Injury.  INFLAMMATION,  43  (5): (1751-1758).  [PMID:32445068]
19. Kaiyao Shi, Yang Liu, Jingru Ma, Yuqing Zhao, Liang Liu, Jingying Wang.  (2020)  A series of aromatric-amine-cored fluorescent emitters for amplified spontaneous laser emission and emission turn-on sensing.  JOURNAL OF LUMINESCENCE,  223  (117165).  [PMID:]
20. Zeng Xin, Zhu Min, Liu Xiaohong, Chen Xuanmin, Yuan Yujia, Li Lan, Liu Jingping, Lu Yanrong, Cheng Jingqiu, Chen Younan.  (2020)  Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis.  Nutrition & Metabolism,  17  (1): (1-14).  [PMID:32021639]
21. Haixia Liu, Qingzhu Yang, Wei Guo, Huiming Lin, Feng Zhang, Jingxiang Zhao, Tianyue Ma, Le Zhao, Na Xu, Ruiwen Wang, Jingyao Yu, Fengyu Qu.  (2020)  CoWO4-x-based nanoplatform for multimode imaging and enhanced photothermal/photodynamic therapy.  CHEMICAL ENGINEERING JOURNAL,  385  (123979).  [PMID:]
22. Yun Li, Yueqin Li, Nana Wang, Dong Lin, Xiaohui Liu, Yong Yang, Qinwei Gao.  (2020)  Synthesis, DNA/BSA binding studies and in vitro biological assay of nickel(II) complexes incorporating tridentate aroylhydrazone and triphenylphosphine ligands.  JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS,  38  (17): (4977-4996).  [PMID:31739745]
23. Haiming Yu, Yuefei Wang, Xiaoqing Wang, Junjie Guo, Hui Wang, Hao Zhang, Fengxia Du.  (2019)  Jatrorrhizine suppresses the antimicrobial resistance of methicillin‑resistant Staphylococcus aureus.  Experimental and Therapeutic Medicine,  18  (5): (3715-3722).  [PMID:31616505]
24. Rui Wang, Xing Hu, Junhui Pan, Guowen Zhang, Deming Gong.  (2019)  Interaction of isoeugenol with calf thymus DNA and its protective effect on DNA oxidative damage.  JOURNAL OF MOLECULAR LIQUIDS,  282  (356).  [PMID:]
25. Zhisheng Zhou, Xing Hu, Guowen Zhang, Rui Wang, Deming Gong.  (2019)  Exploring the binding interaction of Maillard reaction by-product 5-hydroxymethyl-2-furaldehyde with calf thymus DNA.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  99  (6): (3192-3202).  [PMID:30548611]
26. Xunan Jing, Zhe Zhi, Daquan Wang, Jing Liu, Yongping Shao, Lingjie Meng.  (2018)  Multifunctional Nanoflowers for Simultaneous Multimodal Imaging and High-Sensitivity Chemo-Photothermal Treatment.  BIOCONJUGATE CHEMISTRY,  29  (2): (559–570).  [PMID:29376319]
27. Shi-Ying Li, Hong Cheng, Bo-Ru Xie, Wen-Xiu Qiu, Chu-Xin Li, Bin Li, Han Cheng, Xian-Zheng Zhang.  (2017)  Mitochondria targeted cancer therapy using ethidium derivatives.  Materials Today Chemistry,  (34).  [PMID:]
28. Ramachandran Vinayagam, Baojun Xu.  (2017)  7, 8-Dihydroxycoumarin (daphnetin) protects INS-1 pancreatic β-cells against streptozotocin-induced apoptosis.  PHYTOMEDICINE,  24  (119).  [PMID:28160851]
29. Juan Wu, Wei Jiang, Yewen Shen, Wei Jiang, Renbing Tian.  (2017)  Synthesis and characterization of mesoporous magnetic nanocomposites wrapped with chitosan gatekeepers for pH-sensitive controlled release of doxorubicin.  Materials Science & Engineering C-Materials for Biological Applications,  70  (132).  [PMID:27770872]
30. Zhaohui Yang, Min Li, Mingda Yu, Jing Huang, Haiyin Xu, Yan Zhou, Peipei Song, Rui Xu.  (2016)  A novel approach for methylene blue removal by calcium dodecyl sulfate enhanced precipitation and microbial flocculant GA1 flocculation.  CHEMICAL ENGINEERING JOURNAL,  303  (1).  [PMID:]
31. Hailiang Huang, Shuo Shi, Xuyue Zheng, Tianming Yao.  (2015)  Sensitive detection for coralyne and mercury ions based on homo-A/T DNA by exonuclease signal amplification.  BIOSENSORS & BIOELECTRONICS,  71  (439).  [PMID:25950941]
32. Jinhua Zhu, Lanlan Chen, Yingying Dong, Jiazhong Li, Xiuhua Liu.  (2014)  Spectroscopic and molecular modeling methods to investigate the interaction between 5-Hydroxymethyl-2-furfural and calf thymus DNA using ethidium bromide as a probe.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  124  (78).  [PMID:24463243]

Solution Calculators