The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Ethyl 3,4-dihydroxybenzylidenecyanoacetate - ≥96%, high purity , CAS No.132464-92-7
a 12-LO and 15-LO inhibitor
Basic Description Synonyms SCHEMBL9218611 | ethyl (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoate | 2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethyl ester | BDBM50011932 | ethyl (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-2-propenoate | Ethyl (E)-2-cyano-3-(3,4-dihydroxyphenyl)acrylat Specifications & Purity ≥96% Storage Temp Store at 2-8°C Shipped In Wet ice Product Description Ethyl 3,4-dihydroxybenzylidenecyanoacetate is an inhibitor of 12-LO (12-lipoxygenase) and 15-LO (15-lipoxygenase). 12-LO is an enzyme involved in the lipoxygenase pathway and plays a major role in promoting prostate cancer progression and metastasis. 15-LO enzyme has been associated with antherosclerosis and cancer.
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name ethyl (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoate INCHI InChI=1S/C12H11NO4/c1-2-17-12(16)9(7-13)5-8-3-4-10(14)11(15)6-8/h3-6,14-15H,2H2,1H3/b9-5+ InChi Key RAHIHNWEZPLHGV-WEVVVXLNSA-N Canonical SMILES CCOC(=O)C(=CC1=CC(=C(C=C1)O)O)C#N Isomeric SMILES CCOC(=O)/C(=C/C1=CC(=C(C=C1)O)O)/C#N PubChem CID 14840960 Molecular Weight 233.2
Chemical and Physical Properties Solubility Soluble in DMSO, and methanol. Refractive Index n20D1.63 (Predicted) Boil Point(°C) 437.92° C at 760 mmHg (Predicted)
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
