Ethyl nicotinate - 99%, high purity , CAS No.614-18-6

  • ≥99%
Item Number
E104496
Grouped product items
SKUSizeAvailabilityPrice Qty
E104496-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$22.90
E104496-100g
100g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$82.90
E104496-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$369.90

Basic Description

SynonymsEthyl nicotinate | 614-18-6 | ethyl pyridine-3-carboxylate | Ethyl nicotinoate | Ethylnicotinate | Nicotinic acid ethyl ester | 3-Pyridinecarboxylic acid, ethyl ester | Ignicut | Nicotinic acid, ethyl ester | Ethyl 3-pyridinecarboxylate | Mucotherm | Nicaethan | Nikethan | Nikitha
Specifications & Purity≥99%
Storage TempProtected from light,Argon charged
Shipped InNormal
Product Description

Ethyl nicotinate is used for skin-conditioning cosmetics. It is principally used in medicine as a local vasodilator at a concentration of 1 to 2 % in creams, ointments and pomades. It is utilized for the treatment sprains, wrenches, muscular pains and tendonitis.

Associated Targets(non-human)

Thrips tabaci (33 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Thrips obscuratus (68 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name ethyl pyridine-3-carboxylate
INCHI InChI=1S/C8H9NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h3-6H,2H2,1H3
InChi Key XBLVHTDFJBKJLG-UHFFFAOYSA-N
Canonical SMILES CCOC(=O)C1=CN=CC=C1
Isomeric SMILES CCOC(=O)C1=CN=CC=C1
WGK Germany 3
PubChem CID 69188
Molecular Weight 151.16
Beilstein 122937
Reaxy-Rn 122937

Certificates

Certificate of Analysis(COA)

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12 results found

Lot NumberCertificate TypeDateItem
G2417869Certificate of AnalysisApr 01, 2024 E104496
G2417873Certificate of AnalysisApr 01, 2024 E104496
L2129285Certificate of AnalysisOct 09, 2023 E104496
L2129292Certificate of AnalysisOct 09, 2023 E104496
L2129305Certificate of AnalysisOct 09, 2023 E104496
L2129306Certificate of AnalysisOct 09, 2023 E104496
K1920218Certificate of AnalysisJul 17, 2023 E104496
F2121138Certificate of AnalysisApr 12, 2023 E104496
F2121139Certificate of AnalysisApr 12, 2023 E104496
B1920111Certificate of AnalysisSep 21, 2022 E104496
L1411020Certificate of AnalysisJul 12, 2022 E104496
F2316130Certificate of AnalysisDec 09, 2021 E104496

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Chemical and Physical Properties

SolubilitySoluble in water (50 mg/ml at 20 °C).Miscible with water.
SensitivityAir and Light Sensitive
Freezing Point(°C)9 °C
Refractive Index1.504
Flash Point(°F)199.4 °F
Flash Point(°C)93 °C
Boil Point(°C)223-224°C
Melt Point(°C)8-10°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P405:Store locked up.

P501:Dispose of contents/container to ...

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
Reaxy-Rn 122937

Related Documents

References

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3. S Y Chan,A Li Wan Po.  (1993-01-01)  Quantitative evaluation of drug-induced erythema by using a tristimulus colour analyzer: experimental design and data analysis..  Skin pharmacology : the official journal of the Skin Pharmacology Society,  ((4)): (298-312).  [PMID:8198816]
4. K Sugibayashi,T Hayashi,T Hatanaka,M Ogihara,Y Morimoto.  (1996-06-01)  Analysis of simultaneous transport and metabolism of ethyl nicotinate in hairless rat skin..  Pharmaceutical research,  13  ((6)): (855-860).  [PMID:8792422]
5. K Sugibayashi,T Hayashi,Y Morimoto.  (1999-10-16)  Simultaneous transport and metabolism of ethyl nicotinate in hairless rat skin after its topical application: the effect of enzyme distribution in skin..  Journal of controlled release : official journal of the Controlled Release Society,  62  ((1-2)): (201-208).  [PMID:10518652]
6. Tanasait Ngawhirunpat,Praneet Opanasopit,Sompol Prakongpan.  (2004-09-29)  Comparison of skin transport and metabolism of ethyl nicotinate in various species..  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V,  58  ((3)): (645-651).  [PMID:15451540]
7. Zuleikha A M Nworgu,Abiodun Falodun,Cyril O Usifoh.  (2007-08-02)  Inhibitory effect of 3-carboethoxypyridine and 3-carbobutoxypyridine on isolated rat uterus..  Acta poloniae pharmaceutica,  64  ((2)): (179-182).  [PMID:17665869]
8. Ibrahim Uçar,Esat Bozkurt,Canan Kazak,Ahmet Bulut.  (2008-11-18)  Structural characterization and EPR spectral studies on mononuclear copper(II) complex of saccharin with ethylnicotinate..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  72  ((1)): (11-16).  [PMID:19010715]
9. Taylor A Choi,Anna M Furimsky,Robert Swezey,Deborah I Bunin,Patricia Byrge,Lalitha V Iyer,Polly Y Chang,Rebecca J Abergel.  (2015-03-03)  In vitro metabolism and stability of the actinide chelating agent 3,4,3-LI(1,2-HOPO)..  Journal of pharmaceutical sciences,  104  ((5)): (1832-1838).  [PMID:25727482]
10. C M Mills,S A Hill,R Marks.  (1997-07-01)  Transdermal nicotine suppresses cutaneous inflammation..  Archives of dermatology,  133  ((7)): (823-825).  [PMID:9236519]
11. T Ngawhirunpat,T Hatanaka,J Kawakami,I Adachi.  (2001-04-18)  Age difference in simultaneous permeation and metabolism of ethyl nicotinate in rat skin..  Biological & pharmaceutical bulletin,  24  ((4)): (414-417).  [PMID:11305605]
12. Tanasait Ngawhirunpat,Naomi Kawakami,Tomomi Hatanaka,Junichi Kawakami,Isao Adachi.  (2003-09-03)  Age dependency of esterase activity in rat and human keratinocytes..  Biological & pharmaceutical bulletin,  26  ((9)): (1311-1314).  [PMID:12951477]
13. Kenji Sugibayashi,Teruaki Hayashi,Kaori Matsumoto,Tetsuya Hasegawa.  (2004-11-19)  Utility of a three-dimensional cultured human skin model as a tool to evaluate the simultaneous diffusion and metabolism of ethyl nicotinate in skin..  Drug metabolism and pharmacokinetics,  19  ((5)): (352-362).  [PMID:15548846]
14. Tetsuya Hasegawa,Asako Kawazome,Kaori Matsumoto,Go Yanagimoto,Teruaki Hayashi,Masayuki Akimoto,Hiroaki Todo,Kenji Sugibayashi.  (2008-01-08)  Analysis of skin disposition and metabolism of ethyl nicotinate after topical application using dual agar gel disc-inserted rats..  Biological & pharmaceutical bulletin,  31  ((1)): (85-89).  [PMID:18175947]
15. Adel S Girgis,Nawal Mishriky,Ahmad M Farag,Wafaa I El-Eraky,Hanaa Farag.  (2008-02-05)  Synthesis of new 3-pyridinecarboxylates of potential vasodilation properties..  European journal of medicinal chemistry,  43  ((9)): (1818-1827).  [PMID:18241958]

Solution Calculators