Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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E104496-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $22.90 | |
E104496-100g | 100g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $82.90 | |
E104496-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $369.90 |
Synonyms | Ethyl nicotinate | 614-18-6 | ethyl pyridine-3-carboxylate | Ethyl nicotinoate | Ethylnicotinate | Nicotinic acid ethyl ester | 3-Pyridinecarboxylic acid, ethyl ester | Ignicut | Nicotinic acid, ethyl ester | Ethyl 3-pyridinecarboxylate | Mucotherm | Nicaethan | Nikethan | Nikitha |
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Specifications & Purity | ≥99% |
Storage Temp | Protected from light,Argon charged |
Shipped In | Normal |
Product Description | Ethyl nicotinate is used for skin-conditioning cosmetics. It is principally used in medicine as a local vasodilator at a concentration of 1 to 2 % in creams, ointments and pomades. It is utilized for the treatment sprains, wrenches, muscular pains and tendonitis. |
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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IUPAC Name | ethyl pyridine-3-carboxylate |
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INCHI | InChI=1S/C8H9NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h3-6H,2H2,1H3 |
InChi Key | XBLVHTDFJBKJLG-UHFFFAOYSA-N |
Canonical SMILES | CCOC(=O)C1=CN=CC=C1 |
Isomeric SMILES | CCOC(=O)C1=CN=CC=C1 |
WGK Germany | 3 |
PubChem CID | 69188 |
Molecular Weight | 151.16 |
Beilstein | 122937 |
Reaxy-Rn | 122937 |
Enter Lot Number to search for COA:
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Lot Number | Certificate Type | Date | Item |
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G2417869 | Certificate of Analysis | Apr 01, 2024 | E104496 |
G2417873 | Certificate of Analysis | Apr 01, 2024 | E104496 |
L2129285 | Certificate of Analysis | Oct 09, 2023 | E104496 |
L2129292 | Certificate of Analysis | Oct 09, 2023 | E104496 |
L2129305 | Certificate of Analysis | Oct 09, 2023 | E104496 |
L2129306 | Certificate of Analysis | Oct 09, 2023 | E104496 |
K1920218 | Certificate of Analysis | Jul 17, 2023 | E104496 |
F2121138 | Certificate of Analysis | Apr 12, 2023 | E104496 |
F2121139 | Certificate of Analysis | Apr 12, 2023 | E104496 |
B1920111 | Certificate of Analysis | Sep 21, 2022 | E104496 |
L1411020 | Certificate of Analysis | Jul 12, 2022 | E104496 |
F2316130 | Certificate of Analysis | Dec 09, 2021 | E104496 |
Solubility | Soluble in water (50 mg/ml at 20 °C).Miscible with water. |
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Sensitivity | Air and Light Sensitive |
Freezing Point(°C) | 9 °C |
Refractive Index | 1.504 |
Flash Point(°F) | 199.4 °F |
Flash Point(°C) | 93 °C |
Boil Point(°C) | 223-224°C |
Melt Point(°C) | 8-10°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
Reaxy-Rn | 122937 |
1. M Sakamoto,S Yanagi,T Kamiya. (1987-09-15) Inhibitory effects of niacin and its analogues on induction of ornithine decarboxylase activity by diethylnitrosamine in rat liver.. Biochemical pharmacology, 36 ((18)): (3015-3019). [PMID:2888466] |
2. R Fleming,R H Guy,J Hadgraft. (1983-02-01) Kinetics and thermodynamics of interfacial transfer.. Journal of pharmaceutical sciences, 72 ((2)): (142-145). [PMID:6834250] |
3. S Y Chan,A Li Wan Po. (1993-01-01) Quantitative evaluation of drug-induced erythema by using a tristimulus colour analyzer: experimental design and data analysis.. Skin pharmacology : the official journal of the Skin Pharmacology Society, 6 ((4)): (298-312). [PMID:8198816] |
4. K Sugibayashi,T Hayashi,T Hatanaka,M Ogihara,Y Morimoto. (1996-06-01) Analysis of simultaneous transport and metabolism of ethyl nicotinate in hairless rat skin.. Pharmaceutical research, 13 ((6)): (855-860). [PMID:8792422] |
5. K Sugibayashi,T Hayashi,Y Morimoto. (1999-10-16) Simultaneous transport and metabolism of ethyl nicotinate in hairless rat skin after its topical application: the effect of enzyme distribution in skin.. Journal of controlled release : official journal of the Controlled Release Society, 62 ((1-2)): (201-208). [PMID:10518652] |
6. Tanasait Ngawhirunpat,Praneet Opanasopit,Sompol Prakongpan. (2004-09-29) Comparison of skin transport and metabolism of ethyl nicotinate in various species.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 58 ((3)): (645-651). [PMID:15451540] |
7. Zuleikha A M Nworgu,Abiodun Falodun,Cyril O Usifoh. (2007-08-02) Inhibitory effect of 3-carboethoxypyridine and 3-carbobutoxypyridine on isolated rat uterus.. Acta poloniae pharmaceutica, 64 ((2)): (179-182). [PMID:17665869] |
8. Ibrahim Uçar,Esat Bozkurt,Canan Kazak,Ahmet Bulut. (2008-11-18) Structural characterization and EPR spectral studies on mononuclear copper(II) complex of saccharin with ethylnicotinate.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 72 ((1)): (11-16). [PMID:19010715] |
9. Taylor A Choi,Anna M Furimsky,Robert Swezey,Deborah I Bunin,Patricia Byrge,Lalitha V Iyer,Polly Y Chang,Rebecca J Abergel. (2015-03-03) In vitro metabolism and stability of the actinide chelating agent 3,4,3-LI(1,2-HOPO).. Journal of pharmaceutical sciences, 104 ((5)): (1832-1838). [PMID:25727482] |
10. C M Mills,S A Hill,R Marks. (1997-07-01) Transdermal nicotine suppresses cutaneous inflammation.. Archives of dermatology, 133 ((7)): (823-825). [PMID:9236519] |
11. T Ngawhirunpat,T Hatanaka,J Kawakami,I Adachi. (2001-04-18) Age difference in simultaneous permeation and metabolism of ethyl nicotinate in rat skin.. Biological & pharmaceutical bulletin, 24 ((4)): (414-417). [PMID:11305605] |
12. Tanasait Ngawhirunpat,Naomi Kawakami,Tomomi Hatanaka,Junichi Kawakami,Isao Adachi. (2003-09-03) Age dependency of esterase activity in rat and human keratinocytes.. Biological & pharmaceutical bulletin, 26 ((9)): (1311-1314). [PMID:12951477] |
13. Kenji Sugibayashi,Teruaki Hayashi,Kaori Matsumoto,Tetsuya Hasegawa. (2004-11-19) Utility of a three-dimensional cultured human skin model as a tool to evaluate the simultaneous diffusion and metabolism of ethyl nicotinate in skin.. Drug metabolism and pharmacokinetics, 19 ((5)): (352-362). [PMID:15548846] |
14. Tetsuya Hasegawa,Asako Kawazome,Kaori Matsumoto,Go Yanagimoto,Teruaki Hayashi,Masayuki Akimoto,Hiroaki Todo,Kenji Sugibayashi. (2008-01-08) Analysis of skin disposition and metabolism of ethyl nicotinate after topical application using dual agar gel disc-inserted rats.. Biological & pharmaceutical bulletin, 31 ((1)): (85-89). [PMID:18175947] |
15. Adel S Girgis,Nawal Mishriky,Ahmad M Farag,Wafaa I El-Eraky,Hanaa Farag. (2008-02-05) Synthesis of new 3-pyridinecarboxylates of potential vasodilation properties.. European journal of medicinal chemistry, 43 ((9)): (1818-1827). [PMID:18241958] |