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Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid - 99%, high purity , CAS No.67-42-5
Basic Description Synonyms EGTA|67-42-5|Egtazic acid|Gedta|Ethylenebis(oxyethylenenitrilo)tetraacetic acid|Ebonta|6,9-Dioxa-3,12-diazatetradecanedioic acid, 3,12-bis(carboxymethyl)-|1,2-Bis[2-[bis(carboxymethyl)amino]ethoxy]ethane|Ethylene Glycol Tetraacetic Acid|3,12-bis(carboxyme Specifications & Purity AR, ≥99% Shipped In Normal Grade AR Product Description EGTA (Ethylene Glycol Tetraacetic Acid) is a useful chemical in a variety of buffers. EGTA is a chelating agent that can be used for the determination of calcium in the presence of magnesium since EGTA has greater specificity for calcium ions. EGTA is also useful in ELISA reactions as an inhibitor of alkaline phosphatase activity. EGTA has also been shown to activate Ca2+-stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, MMPs (Matrix metalloproteinases).
Names and Identifiers Pubchem Sid 488180021 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488180021 IUPAC Name 2-[2-[2-[2-[bis(carboxymethyl)amino]ethoxy]ethoxy]ethyl-(carboxymethyl)amino]acetic acid INCHI InChI=1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24) InChi Key DEFVIWRASFVYLL-UHFFFAOYSA-N Canonical SMILES C(COCCOCCN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O Isomeric SMILES C(COCCOCCN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O WGK Germany 2 RTECS AH3760000 PubChem CID 6207 Molecular Weight 380.35 Beilstein 1717370 Reaxy-Rn 1717370
Chemical and Physical Properties Solubility Soluble in 1M NaOH (100 mM), Slightly soluble in water. Sensitivity Moisture sensitive. Melt Point(°C) 241°C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
WGK Germany 2 RTECS AH3760000 Reaxy-Rn 1717370 Merck Index 3529
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