Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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E104434-5g | 5g | In stock | $55.90 | |
E104434-25g | 25g | In stock | $137.90 | |
E104434-100g | 100g | In stock | $309.90 | |
E104434-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $927.90 |
Synonyms | [Ethylenebis(oxyethylenenitrilo)]tetraacetic acid | ACETIC ACID, (ETHYLENEBIS(OXYETHYLENENITRILO))TETRA- | Acido egtazico [INN-Spanish] | 3,12-Bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioic acid | Ethylene glycol-bis(2-aminoethyl)-N,N,N',N' |
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Specifications & Purity | for molecular biology, ≥99% |
Shipped In | Normal |
Grade | for molecular biology |
Product Description | EGTA (Ethylene Glycol Tetraacetic Acid) is a useful chemical in a variety of buffers. EGTA is a chelating agent that can be used for the determination of calcium in the presence of magnesium since EGTA has greater specificity for calcium ions. EGTA is also useful in ELISA reactions as an inhibitor of alkaline phosphatase activity. EGTA has also been shown to activate Ca2+-stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, MMPs (Matrix metalloproteinases). |
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IUPAC Name | 2-[2-[2-[2-[bis(carboxymethyl)amino]ethoxy]ethoxy]ethyl-(carboxymethyl)amino]acetic acid |
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INCHI | InChI=1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24) |
InChi Key | DEFVIWRASFVYLL-UHFFFAOYSA-N |
Canonical SMILES | C(COCCOCCN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O |
Isomeric SMILES | C(COCCOCCN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O |
WGK Germany | 2 |
RTECS | AH3760000 |
PubChem CID | 6207 |
Molecular Weight | 380.35 |
Beilstein | 1717370 |
Reaxy-Rn | 1717370 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
K2210273 | Certificate of Analysis | Aug 13, 2024 | E104434 |
G2230258 | Certificate of Analysis | May 15, 2024 | E104434 |
G2230263 | Certificate of Analysis | May 15, 2024 | E104434 |
K2303269 | Certificate of Analysis | Oct 09, 2023 | E104434 |
K2303267 | Certificate of Analysis | Oct 09, 2023 | E104434 |
K2303254 | Certificate of Analysis | Oct 09, 2023 | E104434 |
K2303268 | Certificate of Analysis | Oct 08, 2023 | E104434 |
K2110702 | Certificate of Analysis | Aug 02, 2023 | E104434 |
K2110669 | Certificate of Analysis | Aug 02, 2023 | E104434 |
K2110701 | Certificate of Analysis | Aug 02, 2023 | E104434 |
A2309449 | Certificate of Analysis | Jan 17, 2023 | E104434 |
B2309176 | Certificate of Analysis | Jun 09, 2022 | E104434 |
G2230264 | Certificate of Analysis | Jun 09, 2022 | E104434 |
E2327638 | Certificate of Analysis | Jun 09, 2022 | E104434 |
G2307696 | Certificate of Analysis | Oct 11, 2021 | E104434 |
K2214089 | Certificate of Analysis | Oct 11, 2021 | E104434 |
F2209153 | Certificate of Analysis | Oct 11, 2021 | E104434 |
E2310064 | Certificate of Analysis | Oct 11, 2021 | E104434 |
B2309238 | Certificate of Analysis | Oct 11, 2021 | E104434 |
Sensitivity | Moisture sensitive. |
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Melt Point(°C) | 241°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 2 |
RTECS | AH3760000 |
Reaxy-Rn | 1717370 |
Merck Index | 3529 |
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1. Qiyue Wang, Tao Wang, Shengfei Yang, Hui Du, Bo Zhang, Sirui Cui, Daishun Ling, Fangyuan Li. (2023) Highly Sensitive Diagnosis of Extracellular Calcium Ions Associated Brain Diseases using Ca2+-Dependent T2-T1 Switchable Magnetic Nanosensors. ADVANCED FUNCTIONAL MATERIALS, (2313286). [PMID:] |
2. Ji Wang, Xu-Hui Huang, Yu-Ying Zhang, Chengzhen Nie, Dayong Zhou, Lei Qin. (2024) Mechanism of salt effect on flavor formation in lightly-salted large yellow croaker by integrated multiple intelligent sensory and untargeted lipidomics analyses. FOOD CHEMISTRY, 435 (9): (137542). [PMID:37742462] |
3. Qiaoyu Liu, Menglin Lei, Jianjun Lin, Wenhong Zhao, Xiaofang Zeng, Weidong Bai. (2023) The roles of lipoxygenases and autoxidation during mackerel (Scomberomorus niphonius) dry-cured processing. FOOD RESEARCH INTERNATIONAL, 173 (113309). [PMID:37803620] |
4. Qiaoyu Liu, Menglin Lei, Wenhong Zhao, Xiangluan Li, Xiaofang Zeng, Weidong Bai. (2023) Formation of Lipid-Derived Flavors in Dry-Cured Mackerel (Scomberomorus niphonius) via Simulation of Autoxidation and Lipoxygenase-Induced Fatty Acid Oxidation. Foods, 12 (13): (2504). [PMID:37444242] |
5. Zhiwei Huang, Changju Chun, Xinze Li. (2023) Kidney targeting peptide-modified biomimetic nanoplatforms for treatment of acute kidney injury. JOURNAL OF CONTROLLED RELEASE, 358 (368). [PMID:37121517] |
6. Jingwen Wang, Qiyuan Lu, Junming Gong, Fei Gao, Xinglian Xu, Huhu Wang. (2023) Magnetic field-assisted cascade effects of improving the quality of gels-based meat products: A mechanism from myofibrillar protein gelation. FOOD RESEARCH INTERNATIONAL, 169 (112907). [PMID:37254342] |
7. Li Ting, Jiang Shuhui, Zhang Ying, Luo Jie, Li Ming, Ke Hengte, Deng Yibin, Yang Tao, Sun Xiaohui, Chen Huabing. (2023) Nanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation. Nature Communications, 14 (1): (1-25). [PMID:37120615] |
8. Zhe Chen, Yunxia Wang. (2023) A label- and enzyme-free fluorescence assay based on thioflavin T–induced G-quadruplexes for the detection of telomerase activity. JOURNAL OF CHEMICAL RESEARCH, [PMID:] |
9. Shuai Liu, Yuwei Gao, Lin Quan, Mei Yang, Yong-Zhong Wang, Changjun Hou. (2022) Improvement of Lignocellulolytic Enzyme Production Mediated by Calcium Signaling in Bacillus subtilis Z2 under Graphene Oxide Stress. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 88 (19): [PMID:36121214] |
10. Zhang Zhen, Zhang Haotian, Woon Kok Sin, Zhu Xiaohu, Sui Yuhong, Luo Zifeng, Chen Lili, Yang Xiaoming, Gao Junyi, Wen Hongping, Jing Ran, Liu Tongzhou. (2022) Amendment-Enhanced Phytoextraction of Cadmium from Contaminated Soil Integrating with Ramie as Hyperaccumulator Plant. WATER AIR AND SOIL POLLUTION, 233 (9): (1-16). [PMID:] |
11. Haihua Shang, Yinghui Sun, Ze Wang, Ying Zhou, Huajiao Yang, Xiaoyan Ci, Tao Cui, Yuanyuan Xia, Yuan Gu, Maoliang Liao, Quansheng Li, Duanyun Si, Changxiao Liu. (2022) Intestinal absorption mechanism of rotundic acid: Involvement of P-gp and OATP2B1. JOURNAL OF ETHNOPHARMACOLOGY, 289 (115006). [PMID:35051604] |
12. Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF et al.. (2018) Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.. Elife, 7 (3): (589-97). [PMID:29393851] |
1. Qiyue Wang, Tao Wang, Shengfei Yang, Hui Du, Bo Zhang, Sirui Cui, Daishun Ling, Fangyuan Li. (2023) Highly Sensitive Diagnosis of Extracellular Calcium Ions Associated Brain Diseases using Ca2+-Dependent T2-T1 Switchable Magnetic Nanosensors. ADVANCED FUNCTIONAL MATERIALS, (2313286). [PMID:] |
2. Ji Wang, Xu-Hui Huang, Yu-Ying Zhang, Chengzhen Nie, Dayong Zhou, Lei Qin. (2024) Mechanism of salt effect on flavor formation in lightly-salted large yellow croaker by integrated multiple intelligent sensory and untargeted lipidomics analyses. FOOD CHEMISTRY, 435 (9): (137542). [PMID:37742462] |
3. Qiaoyu Liu, Menglin Lei, Jianjun Lin, Wenhong Zhao, Xiaofang Zeng, Weidong Bai. (2023) The roles of lipoxygenases and autoxidation during mackerel (Scomberomorus niphonius) dry-cured processing. FOOD RESEARCH INTERNATIONAL, 173 (113309). [PMID:37803620] |
4. Qiaoyu Liu, Menglin Lei, Wenhong Zhao, Xiangluan Li, Xiaofang Zeng, Weidong Bai. (2023) Formation of Lipid-Derived Flavors in Dry-Cured Mackerel (Scomberomorus niphonius) via Simulation of Autoxidation and Lipoxygenase-Induced Fatty Acid Oxidation. Foods, 12 (13): (2504). [PMID:37444242] |
5. Zhiwei Huang, Changju Chun, Xinze Li. (2023) Kidney targeting peptide-modified biomimetic nanoplatforms for treatment of acute kidney injury. JOURNAL OF CONTROLLED RELEASE, 358 (368). [PMID:37121517] |
6. Jingwen Wang, Qiyuan Lu, Junming Gong, Fei Gao, Xinglian Xu, Huhu Wang. (2023) Magnetic field-assisted cascade effects of improving the quality of gels-based meat products: A mechanism from myofibrillar protein gelation. FOOD RESEARCH INTERNATIONAL, 169 (112907). [PMID:37254342] |
7. Li Ting, Jiang Shuhui, Zhang Ying, Luo Jie, Li Ming, Ke Hengte, Deng Yibin, Yang Tao, Sun Xiaohui, Chen Huabing. (2023) Nanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation. Nature Communications, 14 (1): (1-25). [PMID:37120615] |
8. Zhe Chen, Yunxia Wang. (2023) A label- and enzyme-free fluorescence assay based on thioflavin T–induced G-quadruplexes for the detection of telomerase activity. JOURNAL OF CHEMICAL RESEARCH, [PMID:] |
9. Shuai Liu, Yuwei Gao, Lin Quan, Mei Yang, Yong-Zhong Wang, Changjun Hou. (2022) Improvement of Lignocellulolytic Enzyme Production Mediated by Calcium Signaling in Bacillus subtilis Z2 under Graphene Oxide Stress. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 88 (19): [PMID:36121214] |
10. Zhang Zhen, Zhang Haotian, Woon Kok Sin, Zhu Xiaohu, Sui Yuhong, Luo Zifeng, Chen Lili, Yang Xiaoming, Gao Junyi, Wen Hongping, Jing Ran, Liu Tongzhou. (2022) Amendment-Enhanced Phytoextraction of Cadmium from Contaminated Soil Integrating with Ramie as Hyperaccumulator Plant. WATER AIR AND SOIL POLLUTION, 233 (9): (1-16). [PMID:] |
11. Haihua Shang, Yinghui Sun, Ze Wang, Ying Zhou, Huajiao Yang, Xiaoyan Ci, Tao Cui, Yuanyuan Xia, Yuan Gu, Maoliang Liao, Quansheng Li, Duanyun Si, Changxiao Liu. (2022) Intestinal absorption mechanism of rotundic acid: Involvement of P-gp and OATP2B1. JOURNAL OF ETHNOPHARMACOLOGY, 289 (115006). [PMID:35051604] |
12. Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF et al.. (2018) Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.. Elife, 7 (3): (589-97). [PMID:29393851] |