Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | Etidronic acid | 2809-21-4 | etidronate | 1-Hydroxyethylidene-1,1-diphosphonic acid | HEDP | EHDP | Etidronsaeure | Acetodiphosphonic acid | Hydroxyethanediphosphonic acid | Turpinal SL | Oxyethylidenediphosphonic acid | Dequest 2015 | Dequest Z 010 | Phosphonic acid, (1-hydroxyet |
|---|---|
| Specifications & Purity | Moligand™, 10mM in Water |
| Biochemical and Physiological Mechanisms | Chelating agent. Shows antioxidant effects as an iron chelator. Reduces osteoclastic activity and prevents bone calcification in vivo. Orally active. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
Associated Targets(Human)
CYP1A2 Tchem Cytochrome P450 1A2 (0 Activities)
DRD2 Tclin D(2) dopamine receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
DRD4 Tchem D(4) dopamine receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ELANE Tclin Neutrophil elastase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
EGFR Tclin Epidermal growth factor receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
AVPR1A Tclin Vasopressin V1a receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
HMGCR Tclin 3-hydroxy-3-methylglutaryl-coenzyme A reductase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
HRH1 Tclin Histamine H1 receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
SLC6A3 Tclin Sodium-dependent dopamine transporter (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
SLC6A4 Tclin Sodium-dependent serotonin transporter (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
PTGS1 Tclin Prostaglandin G/H synthase 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
CA2 Tclin Carbonic anhydrase 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
DRD3 Tclin D(3) dopamine receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
KDR Tclin Vascular endothelial growth factor receptor 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ADRA2B Tclin Alpha-2B adrenergic receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ADRA2C Tclin Alpha-2C adrenergic receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
HTR2A Tclin 5-hydroxytryptamine receptor 2A (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ADORA2A Tclin Adenosine receptor A2a (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ACHE Tclin Acetylcholinesterase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ADRA1B Tclin Alpha-1B adrenergic receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ADRA2A Tclin Alpha-2A adrenergic receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ADRA1A Tclin Alpha-1A adrenergic receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
AR Tclin Androgen receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
MAOA Tclin Amine oxidase [flavin-containing] A (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
AKR1B1 Tclin Aldose reductase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ADORA1 Tclin Adenosine receptor A1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
HTR1A Tclin 5-hydroxytryptamine receptor 1A (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ADORA3 Tchem Adenosine receptor A3 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
HTR6 Tchem 5-hydroxytryptamine receptor 6 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
HTR2B Tclin 5-hydroxytryptamine receptor 2B (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
F2 Tclin Prothrombin (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
EDNRA Tclin Endothelin-1 receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
OPRD1 Tclin Delta-type opioid receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
OPRK1 Tclin Kappa-type opioid receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
OPRM1 Tclin Mu-type opioid receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
NOS2 Tchem Nitric oxide synthase, inducible (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
TACR1 Tclin Substance-P receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
NOS1 Tchem Nitric oxide synthase, brain (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
F2 Tclin Thrombin (11687 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CA2 Tclin Carbonic anhydrase II (17698 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HMGCR Tclin HMG-CoA reductase (2475 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
INSR Tclin Insulin receptor (5558 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PGR Tclin Progesterone receptor (8562 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
AR Tclin Androgen Receptor (11781 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAOA Tclin Monoamine oxidase A (11911 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ACHE Tclin Acetylcholinesterase (18204 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HRH2 Tclin Histamine H2 receptor (5428 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
IMPA1 Tclin Inositol-1(or 4)-monophosphatase 1 (0 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CALCR Tclin Calcitonin receptor (2215 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SLC6A4 Tclin Serotonin transporter (12625 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HRH1 Tclin Histamine H1 receptor (7573 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
OPRM1 Tclin Mu opioid receptor (19785 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
OPRD1 Tclin Delta opioid receptor (15096 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SLC6A3 Tclin Dopamine transporter (10535 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
KCNH2 Tclin HERG (29587 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ESR2 Tclin Estrogen receptor beta (9272 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Associated Targets(non-human)
Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mc4r Melanocortin receptor 4 (1205 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Ltc4s Leukotriene C4 synthase (1 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Sigmar1 Sigma opioid receptor (160 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Cckar Cholecystokinin A receptor (90 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Nos2 Nitric oxide synthase, inducible (3573 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mapk1 MAP kinase ERK2 (650 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Hdac6 Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mmp9 Matrix metalloproteinase 9 (38 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Escherichia coli (133304 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Rattus norvegicus (775804 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Dictyostelium discoideum (81 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
GCN5 Histone acetyltransferase GCN5 (89 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Glra2 Glycine receptor (1745 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
traI Type IV secretion-like conjugative transfer relaxase protein TraI (23 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | (1-hydroxy-1-phosphonoethyl)phosphonic acid |
|---|---|
| INCHI | InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9) |
| InChi Key | DBVJJBKOTRCVKF-UHFFFAOYSA-N |
| Canonical SMILES | CC(O)(P(=O)(O)O)P(=O)(O)O |
| Isomeric SMILES | CC(O)(P(=O)(O)O)P(=O)(O)O |
| WGK Germany | 2 |
| RTECS | SZ8562100 |
| Alternate CAS | 25211-86-3 |
| PubChem CID | 3305 |
| UN Number | 3265 |
| Molecular Weight | 206.03 |
| Beilstein | 1789291 |
| Reaxy-Rn | 1789291 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Boil Point(°C) | 105 °C |
|---|---|
| Melt Point(°C) | -40 °C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS05 |
|---|---|
| Signal | Danger |
| Hazard Statements | H413:May cause long lasting harmful effects to aquatic life H318:Causes serious eye damage |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
| WGK Germany | 2 |
| RTECS | SZ8562100 |
| Reaxy-Rn | 1789291 |
| Merck Index | 3863 |
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| 2. Chenhao Ni, Ningyi Chen, Jiahui He, Meilan Pan, Xianhua Wang, Bingjun Pan. (2023) Complexation-based selectivity of organic phosphonates adsorption from high-salinity water by neodymium-doped nanocomposite. WATER RESEARCH, 246 (120705). [PMID:37827040] [10.1016/j.watres.2023.120705] |
| 3. Jiahui Wu, Longhua Xu, Donghui Wang, Kai Xue, Xinzhang Shi, Lin Peng, Jiushuai Deng. (2023) Selective adsorption of 1-hydroxyethylidene-1,1-diphosphonic acid on calcite surface in smithsonite flotation system. MINERALS ENGINEERING, 203 (108326). [PMID:] [10.1016/j.mineng.2023.108326] |
| 4. Ping Li, Hui Guo, Peng Sun, Xulei Zhi, Zhongfang Li. (2023) Proton transfer efficiency enhanced over wide relative humidity: Etidronic acid-modified polyphosphazenes cross-linked polybenzimidazoles membranes. JOURNAL OF MEMBRANE SCIENCE, 685 (121973). [PMID:] [10.1016/j.memsci.2023.121973] |
| 5. Ziqiang Wang, Guanghui Yang, Pengjun Tian, Xinmiao Li, Kai Deng, Hongjie Yu, You Xu, Hongjing Wang, Liang Wang. (2023) Hydrophilic functionalization of rhodium metallene for saving-energy hydrogen production and sulfur recovery. CHEMICAL ENGINEERING JOURNAL, 473 (145147). [PMID:] [10.1016/j.cej.2023.145147] |
| 6. Fang-Jun Cao, Xiang Hou, Kai-Feng Wang, Tie-Zhi Jin, Hui Feng. (2023) Facile synthesis of phosphorus and nitrogen co-doped carbon dots with excellent fluorescence emission towards cellular imaging. RSC Advances, 13 (30): (21088-21095). [PMID:37448635] [10.1039/D3RA03361A] |
| 7. Junyu Qian, Haotian Qin, Peijie Zeng, Jiaming Hou, Xiaoshan Mo, Gang Shen, Hui Zeng, Wentai Zhang, Yingqi Chen, Guojiang Wan. (2023) Metal-organic Zn-zoledronic acid and 1-hydroxyethylidene-1,1-diphosphonic acid nanostick-mediated zinc phosphate hybrid coating on biodegradable Zn for osteoporotic fracture healing implants. Acta Biomaterialia, [PMID:37196904] [10.1016/j.actbio.2023.05.020] |
| 8. Jiazhi Yang, Xuejun Long, Xiaonan Feng, Jun Wan. (2023) Simultaneous sorption of orthophosphate and phosphonate from RO concentrate by kaolin/lanthanum carbonate composites: Experimental investigation and multi-objective artificial neural network modeling. Journal of Environmental Chemical Engineering, 11 (109776). [PMID:] [10.1016/j.jece.2023.109776] |
| 9. Wen-Yuan Fan, Xin Zhang, Pu-Can Guo, Guo-Ping Sheng. (2023) Highly efficient removal of phosphonates by ferrate-induced oxidation coupled with in situ coagulation. JOURNAL OF HAZARDOUS MATERIALS, 451 (131104). [PMID:36870127] [10.1016/j.jhazmat.2023.131104] |
| 10. Shunlong Pan, Xinrui Guo, Xing Lu, Rong Li, Hao Hu, Xi Nie, Biming Liu, Rong Chen, Mingxin Zhu, Shengqiang Hei, Xianzheng Zhu, Shuo Zhang, Hua Zhou. (2023) Boosting peroxymonosulfate activation by a novel bifunctional core-shell nanoreactor MnFe2O4@HZO for nitrilotris-methylenephosphonic acid removal. APPLIED CATALYSIS B-ENVIRONMENTAL, 330 (122508). [PMID:] [10.1016/j.apcatb.2023.122508] |
| 11. Zhusong Xu, Haoze Wang, Huanqi Kang, Luyuan Zhao, Xiaodong Liu, Wenbing Huang, Yasong Zhou, Qiang Wei. (2023) Effect of organic phosphorus addition on the state of active metal species and catalytic performance of NiW/Al2O3 hydrodesulfurization catalyst. FUEL, 340 (127547). [PMID:] [10.1016/j.fuel.2023.127547] |
| 12. Junrui Chi, Yu Zhang, Shutong Yu, Aoyu Ju, Yanghao Li, Huizhen Zhi, Jinfei Yang. (2023) The thermal and combustion properties of soybean oil phosphate-based polyurethane foam composites containing polyol of etidronic acid. REACTIVE & FUNCTIONAL POLYMERS, 183 (105499). [PMID:] [10.1016/j.reactfunctpolym.2023.105499] |
| 13. Guangsheng Zeng, Wei Chen, Sheng Liu, Guangyi Liu. (2023) New insights into the aggregation and disaggregation between serpentine and pyrite in the xanthate flotation system. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 633 (243). [PMID:36459931] [10.1016/j.jcis.2022.11.123] |
| 14. Xukun Zhang, Fancheng Meng, Linquan Sun, Zhaowu Zhu, Desheng Chen, Lina Wang. (2022) Influence of Several Phosphate-Containing Additives on the Stability and Electrochemical Behavior of Positive Electrolytes for Vanadium Redox Flow Battery. Energies, 15 (21): (7829). [PMID:] [10.3390/en15217829] |
| 15. Kaixiang Cui, Yufei Xia, Linlin Tian, Shuai Wang, Yongyao He. (2022) Effect of supercritical CO2 flooding on the produced water quality and performance of the scale inhibitors in a typical tight sandstone oilfield. PETROLEUM SCIENCE AND TECHNOLOGY, [PMID:] [10.1080/10916466.2022.2032150] |
| 16. Zemeng Dong, Xue Jiang, Wen Zhang, Jing Wang, Guang-Rui Xu, Zexing Wu, Guangjiu Li, Lei Wang. (2022) Organic phosphoric acid induced coral-like palladium network nanostructures for superior polyhydric alcohols electrocatalysis. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 623 (1122). [PMID:] [10.1016/j.jcis.2022.05.077] |
| 17. Luo Qie, Cui Wenzheng, Wang Huan, Xiao Bo, Chen Lei, Wang Youqun, Zhang Zhibin, Liu Yunhai, Cao Xiaohong. (2022) Efficient capture of U(VI) by magnetic Zr(IV)-ethylenediamine tetramethylene phosphonic acid inorganic-organic hybrid. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 29 (45): (68320-68331). [PMID:35536467] [10.1007/s11356-022-20548-9] |
| 18. Huanyu Zhu, Bingqiao Yang, Jinchan Feng, Feifei Jia. (2021) Evaluation of 1-hydroxyethylidene-1,1-diphosphonic acid as an efficient and low-toxic sphalerite depressant in the selective flotation of galena from sphalerite. Journal of Cleaner Production, 329 (129612). [PMID:] [10.1016/j.jclepro.2021.129612] |
| 19. Liang-ping Xiong, Mei Gu, Chu-ting Yang, Kai Lv, Feng-cheng Wu, Sheng Hu, Xing-gui Long. (2022) Metal phosphonate sorbents: Enhancement of actinide sorption performance by gamma irradiation. CHEMICAL ENGINEERING JOURNAL, 430 (132753). [PMID:] [10.1016/j.cej.2021.132753] |
| 20. Weibo Huang, Yan Wang, Linze Lv, Wei Wang, Chengchang Jin, Guobin Zhu, Qiang Shi, Qunting Qu, Chao Jin, Honghe Zheng. (2021) 1-Hydroxyethylidene-1, 1-diphosphonic acid: A multifunctional interface modifier for eliminating HF in silicon anode. Energy Storage Materials, 42 (493). [PMID:] [10.1016/j.ensm.2021.08.010] |
| 21. Jincan Cui, Zhi Xiong, Hanxun Qiu, Jing LI, Junhe Yang. (2021) Functionalized graphene oxide: Carrier for corrosion inhibitor and barrier in waterborne epoxy coatings. COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING, 144 (106354). [PMID:] [10.1016/j.compositesa.2021.106354] |
| 22. Deng Wang, Jiaxin Yang, Fei Xue, Jihui Wang, Wenbin Hu. (2021) Experimental and computational study of zinc coordinated 1-hydroxyethylidene-1,1-diphosphonic acid self-assembled film on steel surface. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 612 (126009). [PMID:] [10.1016/j.colsurfa.2020.126009] |
| 23. Xin Hu, Meixian Li, Jie Yang, Feng Liu, Hao Huang, Haifeng Pan, Hongyu Yang. (2021) In situ fabrication of melamine hydroxy ethylidene diphosphonate wrapped montmorillonite for reducing the fire hazards of epoxy resin. APPLIED CLAY SCIENCE, 201 (105934). [PMID:] [10.1016/j.clay.2020.105934] |
| 24. Jianjun Wang, Wenheng Li, Zihan Zhou, Zhiyong Gao, Yuehua Hu, Wei Sun. (2020) 1-Hydroxyethylidene-1,1-diphosphonic acid used as pH-dependent switch to depress and activate fluorite flotation I: Depressing behavior and mechanism. CHEMICAL ENGINEERING SCIENCE, 214 (115369). [PMID:] [10.1016/j.ces.2019.115369] |
| 25. Wen Zhang, An Bu, Qingyuan Ji, Luofu Min, Song Zhao, Yuxin Wang, Jing Chen. (2019) pKa-Directed Incorporation of Phosphonates into MOF-808 via Ligand Exchange: Stability and Adsorption Properties for Uranium. ACS Applied Materials & Interfaces, 11 (37): (33931–33940). [PMID:31409065] [10.1021/acsami.9b10920] |
| 26. Shimin Pu, Meiyun Chen, Yingqi Chen, Wentai Zhang, Hanaa Soliman, Ai Qu, Qijun Liu, Xin Tang, Nan Huang, Guojiang Wan. (2018) Zirconium ions integrated in 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) as a metalorganic-like complex coating on biodegradable magnesium for corrosion control. CORROSION SCIENCE, 144 (277). [PMID:] [10.1016/j.corsci.2018.09.003] |
| 27. Junchen Su, Yang Zhao, Jingyu Xi. (2018) Phosphorus-doped carbon nitride as powerful electrocatalyst for high-power vanadium flow battery. ELECTROCHIMICA ACTA, 286 (22). [PMID:] [10.1016/j.electacta.2018.08.044] |
| 28. Jianjun Wang, Zihan Zhou, Yuesheng Gao, Wei Sun, Yuehua Hu, Zhiyong Gao. (2018) Reverse Flotation Separation of Fluorite from Calcite: A Novel Reagent Scheme. Minerals, 8 (8): (313). [PMID:] [10.3390/min8080313] |
| 29. Cao JiaLi, Ni Liang, Qin CanCan, Tang YueFeng, Chen YanFeng. (2017) Synthesis of hierarchical Na2FeP2O7 spheres with high electrochemical performance via spray drying. IONICS, 23 (7): (1783-1791). [PMID:] [10.1007/s11581-017-2020-2] |
| 30. Meiyun Chen, Yingqi Chen, Wentai Zhang, Sheng Zhao, Juan Wang, Jinlong Mao, Wei Li, Yuancong Zhao, Nan Huang, Guojiang Wan. (2016) Controlling the corrosion rate and behavior of biodegradable magnesium by a surface-immobilized ultrathin 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) film. RSC Advances, 6 (18): (15247-15259). [PMID:] [10.1039/C5RA23228G] |
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| 15. Kaixiang Cui, Yufei Xia, Linlin Tian, Shuai Wang, Yongyao He. (2022) Effect of supercritical CO2 flooding on the produced water quality and performance of the scale inhibitors in a typical tight sandstone oilfield. PETROLEUM SCIENCE AND TECHNOLOGY, [PMID:] [10.1080/10916466.2022.2032150] |
| 16. Zemeng Dong, Xue Jiang, Wen Zhang, Jing Wang, Guang-Rui Xu, Zexing Wu, Guangjiu Li, Lei Wang. (2022) Organic phosphoric acid induced coral-like palladium network nanostructures for superior polyhydric alcohols electrocatalysis. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 623 (1122). [PMID:] [10.1016/j.jcis.2022.05.077] |
| 17. Luo Qie, Cui Wenzheng, Wang Huan, Xiao Bo, Chen Lei, Wang Youqun, Zhang Zhibin, Liu Yunhai, Cao Xiaohong. (2022) Efficient capture of U(VI) by magnetic Zr(IV)-ethylenediamine tetramethylene phosphonic acid inorganic-organic hybrid. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 29 (45): (68320-68331). [PMID:35536467] [10.1007/s11356-022-20548-9] |
| 18. Huanyu Zhu, Bingqiao Yang, Jinchan Feng, Feifei Jia. (2021) Evaluation of 1-hydroxyethylidene-1,1-diphosphonic acid as an efficient and low-toxic sphalerite depressant in the selective flotation of galena from sphalerite. Journal of Cleaner Production, 329 (129612). [PMID:] [10.1016/j.jclepro.2021.129612] |
| 19. Liang-ping Xiong, Mei Gu, Chu-ting Yang, Kai Lv, Feng-cheng Wu, Sheng Hu, Xing-gui Long. (2022) Metal phosphonate sorbents: Enhancement of actinide sorption performance by gamma irradiation. CHEMICAL ENGINEERING JOURNAL, 430 (132753). [PMID:] [10.1016/j.cej.2021.132753] |
| 20. Weibo Huang, Yan Wang, Linze Lv, Wei Wang, Chengchang Jin, Guobin Zhu, Qiang Shi, Qunting Qu, Chao Jin, Honghe Zheng. (2021) 1-Hydroxyethylidene-1, 1-diphosphonic acid: A multifunctional interface modifier for eliminating HF in silicon anode. Energy Storage Materials, 42 (493). [PMID:] [10.1016/j.ensm.2021.08.010] |
| 21. Jincan Cui, Zhi Xiong, Hanxun Qiu, Jing LI, Junhe Yang. (2021) Functionalized graphene oxide: Carrier for corrosion inhibitor and barrier in waterborne epoxy coatings. COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING, 144 (106354). [PMID:] [10.1016/j.compositesa.2021.106354] |
| 22. Deng Wang, Jiaxin Yang, Fei Xue, Jihui Wang, Wenbin Hu. (2021) Experimental and computational study of zinc coordinated 1-hydroxyethylidene-1,1-diphosphonic acid self-assembled film on steel surface. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 612 (126009). [PMID:] [10.1016/j.colsurfa.2020.126009] |
| 23. Xin Hu, Meixian Li, Jie Yang, Feng Liu, Hao Huang, Haifeng Pan, Hongyu Yang. (2021) In situ fabrication of melamine hydroxy ethylidene diphosphonate wrapped montmorillonite for reducing the fire hazards of epoxy resin. APPLIED CLAY SCIENCE, 201 (105934). [PMID:] [10.1016/j.clay.2020.105934] |
| 24. Jianjun Wang, Wenheng Li, Zihan Zhou, Zhiyong Gao, Yuehua Hu, Wei Sun. (2020) 1-Hydroxyethylidene-1,1-diphosphonic acid used as pH-dependent switch to depress and activate fluorite flotation I: Depressing behavior and mechanism. CHEMICAL ENGINEERING SCIENCE, 214 (115369). [PMID:] [10.1016/j.ces.2019.115369] |
| 25. Wen Zhang, An Bu, Qingyuan Ji, Luofu Min, Song Zhao, Yuxin Wang, Jing Chen. (2019) pKa-Directed Incorporation of Phosphonates into MOF-808 via Ligand Exchange: Stability and Adsorption Properties for Uranium. ACS Applied Materials & Interfaces, 11 (37): (33931–33940). [PMID:31409065] [10.1021/acsami.9b10920] |
| 26. Shimin Pu, Meiyun Chen, Yingqi Chen, Wentai Zhang, Hanaa Soliman, Ai Qu, Qijun Liu, Xin Tang, Nan Huang, Guojiang Wan. (2018) Zirconium ions integrated in 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) as a metalorganic-like complex coating on biodegradable magnesium for corrosion control. CORROSION SCIENCE, 144 (277). [PMID:] [10.1016/j.corsci.2018.09.003] |
| 27. Junchen Su, Yang Zhao, Jingyu Xi. (2018) Phosphorus-doped carbon nitride as powerful electrocatalyst for high-power vanadium flow battery. ELECTROCHIMICA ACTA, 286 (22). [PMID:] [10.1016/j.electacta.2018.08.044] |
| 28. Jianjun Wang, Zihan Zhou, Yuesheng Gao, Wei Sun, Yuehua Hu, Zhiyong Gao. (2018) Reverse Flotation Separation of Fluorite from Calcite: A Novel Reagent Scheme. Minerals, 8 (8): (313). [PMID:] [10.3390/min8080313] |
| 29. Cao JiaLi, Ni Liang, Qin CanCan, Tang YueFeng, Chen YanFeng. (2017) Synthesis of hierarchical Na2FeP2O7 spheres with high electrochemical performance via spray drying. IONICS, 23 (7): (1783-1791). [PMID:] [10.1007/s11581-017-2020-2] |
| 30. Meiyun Chen, Yingqi Chen, Wentai Zhang, Sheng Zhao, Juan Wang, Jinlong Mao, Wei Li, Yuancong Zhao, Nan Huang, Guojiang Wan. (2016) Controlling the corrosion rate and behavior of biodegradable magnesium by a surface-immobilized ultrathin 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) film. RSC Advances, 6 (18): (15247-15259). [PMID:] [10.1039/C5RA23228G] |