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Etodolac - ≥98%, high purity , Cyclooxygenase-2 inhibitor, CAS No.41340-25-4, Cyclooxygenase-2 inhibitor

  • Moligand™
  • ≥98%
Item Number
E129317
Grouped product items
SKUSizeAvailabilityPrice Qty
E129317-200mg
200mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$9.90
E129317-1g
1g
In stock
$22.90
E129317-5g
5g
In stock
$87.90
E129317-25g
25g
In stock
$218.90
E129317-100g
100g
In stock
$786.90

COX-2 inhibitor; NSAID

View related series
COX-2 Inhibitor

Basic Description

Synonymsetodolac|41340-25-4|Etodolic acid|Lodine|Ultradol|Lodine XL|Edolan|AY-24236|Etodolaco|Etodolacum|Ramodar|Tedolan|Zedolac|AY-24,236|Eccoxolac|Flancox|Napilac|rac-Etodolac|Lodin xl|AY 24236|Etodolacum [INN-Latin]|Etodolaco [INN-Spanish]|(rs)-etodolic acid|2
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsEtodolac is a Cox-2 inhibitor with anti-inflammatory and analgesic activity. Etodolac is shown to inhibit growth and PCNA expression and induce cell cycle arrest in human hepatocellular carcinoma cell lines, in addition to suppressing the occurrence of ab
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionCyclooxygenase-2 inhibitor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Etodolac is a COX inhibitor with an IC50 of 53.5 nM.

Product Properties

ALogP2.8

Names and Identifiers

IUPAC Name 2-(1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid
INCHI InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)
InChi Key NNYBQONXHNTVIJ-UHFFFAOYSA-N
Canonical SMILES CCC1=C2C(=CC=C1)C3=C(N2)C(OCC3)(CC)CC(=O)O
Isomeric SMILES CCC1=C2C(=CC=C1)C3=C(N2)C(OCC3)(CC)CC(=O)O
WGK Germany 3
RTECS UQ0360000
PubChem CID 3308
Molecular Weight 287.35
Reaxy-Rn 928311

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

6 results found

Lot NumberCertificate TypeDateItem
L2114297Certificate of AnalysisSep 22, 2023 E129317
L2114298Certificate of AnalysisSep 22, 2023 E129317
L2114299Certificate of AnalysisSep 22, 2023 E129317
K1709060Certificate of AnalysisMay 10, 2023 E129317
F1526060Certificate of AnalysisJan 18, 2023 E129317
F2217250Certificate of AnalysisJun 30, 2022 E129317

Chemical and Physical Properties

SolubilitySoluble in DMSO (100 mM), and ethanol (100 mM).
SensitivityLight & Heat sensitive
Melt Point(°C)148°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS07
Signal Danger
Hazard Statements

H319:Causes serious eye irritation

H301:Toxic if swallowed

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 3
RTECS UQ0360000
Reaxy-Rn 928311
Merck Index 3874

Related Documents

Solution Calculators