Everolimus - ≥98%, high purity , FK506-binding protein 1A inhibitor, CAS No.159351-69-6, FK506-binding protein 1A inhibitor

Item Number

E125341

• Synonyms: 001, RAD | 40-O-(2-hydroxyethyl)-rapamycin | 40-O-(2-Hydroxyethyl)rapamycin | Afinitor | Certican | Everolimus | RAD | RAD 001 | RAD, SDZ | RAD001 | SDZ RAD | SDZ-RAD | Zortress | 159351-69-6 | Votubia | 42-O-(2-Hydroxyethyl)rapamycin | RAD-001 | everolimusum | CHEBI:68478 | Afinitor Disperz |
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Everolimus is a macrolide derived from rapamycin with immunosuppressant properties shown to inhibit cell proliferation induced by growth factors. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthe
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: FK506-binding protein 1A inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM.
An immunosuppresive inhibitor of FRAP (mTOR).