The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
EXP 3174 - ≥98%(HPLC), high purity , CAS No.124750-92-1, Antagonist of AT 1 receptor
Potent and selective AT1antagonist
Basic Description Synonyms Losartan carboxylic acid|124750-92-1|EXP-3174|Exp3174|EXP 3174|E-3174|Carboxylosartan|CHEBI:74125|2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid|CHEMBL907|GD76OCH73X|2-Butyl-4-chloro-1-[(2'-(1-H-tetrazol-5-yl) Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms Potent and selective noncompetitive AT1receptor antagonist (IC50= 37 nM). Reduces blood pressure in a rat model. Active metabolite oflosartan potassium. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type ANTAGONIST Mechanism of action Antagonist of AT 1 receptor
Names and Identifiers IUPAC Name 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid INCHI InChI=1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28) InChi Key ZEUXAIYYDDCIRX-UHFFFAOYSA-N Canonical SMILES CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)Cl Isomeric SMILES CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)Cl PubChem CID 108185 Molecular Weight 436.89
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 43.69, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 43.69, Max Conc. mM: 100
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
H2206701