Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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F100149-1g | 1g | In stock | $58.90 | |
F100149-5g | 5g | In stock | $82.90 | |
F100149-25g | 25g | In stock | $336.90 | |
F100149-100g | 100g | In stock | $1,210.90 | |
F100149-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $5,445.90 |
RNA and DNA synthesis inhibitor. Anticancer agent.
Synonyms | 5-FU | 5-Fluorouracil-6-d1 | fluorouracil | NSC19893 | NSC-19893 | 5-Fluoracil | Cinco FU | Fluro Uracil | U3P01618RT | 5-Fluor-2,4(1H,3H)-pyrimidindion | 5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione | FU | AI3-25297 | Fluorouracile [DCIT] | HSDB 3228 |
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Specifications & Purity | Moligand™, ≥99% |
Biochemical and Physiological Mechanisms | 5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | RNA inhibitor |
Note | 1g卖完停产,不再备货Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488179764 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179764 |
IUPAC Name | 5-fluoro-1H-pyrimidine-2,4-dione |
INCHI | InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9) |
InChi Key | GHASVSINZRGABV-UHFFFAOYSA-N |
Canonical SMILES | C1=C(C(=O)NC(=O)N1)F |
Isomeric SMILES | C1=C(C(=O)NC(=O)N1)F |
WGK Germany | 3 |
RTECS | YR0350000 |
PubChem CID | 3385 |
Molecular Weight | 130.08 |
Beilstein | 127172 |
Reaxy-Rn | 127172 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
F2406187 | Certificate of Analysis | Mar 23, 2024 | F100149 |
F2406188 | Certificate of Analysis | Mar 23, 2024 | F100149 |
I2307513 | Certificate of Analysis | Aug 24, 2023 | F100149 |
I2307514 | Certificate of Analysis | Aug 24, 2023 | F100149 |
I2307515 | Certificate of Analysis | Aug 24, 2023 | F100149 |
L2312019 | Certificate of Analysis | Nov 21, 2022 | F100149 |
L2209512 | Certificate of Analysis | Nov 21, 2022 | F100149 |
L2209500 | Certificate of Analysis | Nov 21, 2022 | F100149 |
L2209422 | Certificate of Analysis | Nov 21, 2022 | F100149 |
L2209421 | Certificate of Analysis | Nov 21, 2022 | F100149 |
L2209326 | Certificate of Analysis | Nov 21, 2022 | F100149 |
L2209319 | Certificate of Analysis | Nov 21, 2022 | F100149 |
L2209316 | Certificate of Analysis | Nov 21, 2022 | F100149 |
G2311074 | Certificate of Analysis | Nov 21, 2022 | F100149 |
D2312006 | Certificate of Analysis | Nov 21, 2022 | F100149 |
B2309110 | Certificate of Analysis | Nov 21, 2022 | F100149 |
I2220091 | Certificate of Analysis | Nov 27, 2021 | F100149 |
I2220086 | Certificate of Analysis | Nov 27, 2021 | F100149 |
B2309109 | Certificate of Analysis | Nov 27, 2021 | F100149 |
Solubility | Soluble in dimethylformamide, dimethyl sulfoxide, methanol, hot water, ammonium hydroxide, sodium hydroxide, ethanol and water.Water solubility: 12.2 g/L (20°C) |
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Sensitivity | Light sensitive. |
Boil Point(°C) | 190 - 200 °C / 374 - 392 °F@ 0.1 mmHg |
Melt Point(°C) | 278 - 282 °C / 532.4 - 539.6 °F |
Pictogram(s) | GHS06, GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed H412:Harmful to aquatic life with long lasting effects H312:Harmful in contact with skin H360:May damage fertility or the unborn child H340:May cause genetic defects |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P281:Use personal protective equipment as required. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | YR0350000 |
Reaxy-Rn | 127172 |
Merck Index | 4181 |
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