| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| F420391-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $143.90 |
Aromatase Inhibitors
| Synonyms | FADROZOLE|102676-47-1|4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile|CGS-16949A|Fadrozole [INN]|Benzonitrile, 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)-|CHEMBL9298|FAD 286A|Fadrozole (INN)|H3988M64PU|4-{5H,6H,7H,8H-imidazo[1,5-a]pyrid |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Fadrozole (CGS16949A) is a potent, selective, nonsteroidal inhibitor of aromatase with an IC50 of 4.5 nM and selectivity over other cytochrome P-450 enzymes. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
| Product Description | Information Fadrozole (CGS16949A) Fadrozole (CGS16949A) is a potent, selective, nonsteroidal inhibitor of aromatase with an IC50 of 4.5 nM and selectivity over other cytochrome P-450 enzymes. Targets Aromatase 4.5 nM |
| ALogP | 2.271 |
|---|---|
| Rotatable Bond | 1 |
| IUPAC Name | 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile |
|---|---|
| INCHI | InChI=1S/C14H13N3/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14/h4-7,9-10,14H,1-3H2 |
| InChi Key | CLPFFLWZZBQMAO-UHFFFAOYSA-N |
| Canonical SMILES | C1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N |
| Isomeric SMILES | C1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N |
| PubChem CID | 59693 |
| Molecular Weight | 223.27 |
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| DMSO(mg / mL) Max Solubility | 45 |
|---|---|
| DMSO(mM) Max Solubility | 201.549693196578 |
| Water(mg / mL) Max Solubility | ＜1 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
