Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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F129242-5g | 5g | In stock | $132.90 | |
F129242-25g | 25g | In stock | $598.90 |
Selective H 2 antagonist
Synonyms | Dipsin | Famogard | Famovane | Nevofam | Pepdif | 4-14-00-00308 (Beilstein Handbook Reference) | Evatin | Famosan | Purifam | Fibonel | Lecedil | Pepcid RPD | 3-Picoline, .alpha.-chloro- | Dispronil | Famopsin | Hacip | Mensoma | MFCD00016818 | Motiax | Y |
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Specifications & Purity | Moligand™, ≥99% |
Biochemical and Physiological Mechanisms | Selective H 2 receptor antagonist. Shows antiulcer and antioxidant properties. Enhances angiogenesis. |
Storage Temp | Protected from light |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | AGONIST, ANTAGONIST |
Mechanism of action | Histamine H2 receptor antagonist |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Famotidine is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions. |
ALogP | -0.6 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488195592 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488195592 |
IUPAC Name | 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N'-sulfamoylpropanimidamide |
INCHI | InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14) |
InChi Key | XUFQPHANEAPEMJ-UHFFFAOYSA-N |
Canonical SMILES | C1=C(N=C(S1)N=C(N)N)CSCCC(=NS(=O)(=O)N)N |
Isomeric SMILES | C1=C(N=C(S1)N=C(N)N)CSCC/C(=N/S(=O)(=O)N)/N |
WGK Germany | 2 |
RTECS | UA2300000 |
PubChem CID | 5702160 |
Molecular Weight | 337.45 |
Reaxy-Rn | 7226206 |
DrugBank Ligand | DB00927 |
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PubChem CID | 5702160 |
CAS Registry No. | 76824-35-6 |
ChEMBL Ligand | CHEMBL902 |
Wikipedia | Famotidine |
ChEBI | CHEBI:4975 |
BitterDB Ligand | 101 |
PEP | famotidine |
DrugCentral Ligand | 1129 |
GPCRdb Ligand | famotidine |
PubChem SID | 488195592 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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D2314317 | Certificate of Analysis | Mar 15, 2023 | F129242 |
D2314343 | Certificate of Analysis | Mar 15, 2023 | F129242 |
D2314416 | Certificate of Analysis | Mar 15, 2023 | F129242 |
G1521008 | Certificate of Analysis | Feb 03, 2023 | F129242 |
Solubility | DMSO 67 mg/mL (198.54 mM);Water <1 mg/mL (<1 mM);Ethanol <1 mg/mL (<1 mM) |
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Sensitivity | light sensitive |
Melt Point(°C) | 166-168°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H332:Harmful if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 2 |
RTECS | UA2300000 |
Reaxy-Rn | 7226206 |